Areas of Focus
- Development of biotechnological drugs
- Development and application of bispecific antibodies in tumor immunotherapy
- Regulatory role of Brd2 in glucose and lipid metabolism
Work Experience
- 2007.9-Present - Fudan University, Key Laboratory of Molecular Medicine, Professor
- 2002/4-2007/8 - Harvard Medical School, Postdoctoral Researcher
- 1997/7-1998/8 - Shanghai Industrial Medical Biotechnology Co., Ltd., Deputy General Manager, Senior Engineer
- 1983/7-1994/8 - Taishan Medical University, Lecturer
Academic Background & Achievements
- 1998/9-2002/1 PhD: Fudan University, School of Medicine, Biochemistry and Molecular Biology
- 1994/9-1997/7 Master's: Shanghai Medical University, Biochemistry and Molecular Biology
- 1979/9-1983/7 Bachelor's: East China Normal University, Chemistry
Publications
- Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease, Mengfang Wu, Tian Xia, Yaran Li, Tianfa Wang, Shijia Yang, Jinchao Yu, Qiaoyan Liang, Teng Shen, Min Yu, Bing Zhao, 2022
- Development of bispecific anti-c-Met/PD-1 diabodies for the treatment of solid tumors and the effect of c-Met binding affinity on efficacy, Qingyun Yuan, Qiaoyan Liang, Zujun Sun, Xingxing Yuan, Weihua Hou, Yuxiong Wang, Huijie Wang, Min Yu, 2021
- A novel oncotherapy strategy, direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer, Bing Zhao, Mengfang Wu, Zhihuang Hu, Tianfa Wang, Jinchao Yu, Yixin Ma, Qi Wang, Yanling Zhang, Di Chen, Tianyu Li, Yaran Li, Min Yu, Huijie Wang, Wei Mo, 2021
- A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer, Weihua Hou, Qingyun Yuan, Xingxing Yuan, Yuxiong Wang, Wei Mo, Huijie Wang, Min Yu, 2019
- Bromodomain-containing protein 2 induces insulin resistance via the mTOR/Akt signaling pathway and an inflammatory response in adipose tissue, Ruixin Sun, Yi Wu, Weihua Hou, Zujun Sun, Yuxiong Wang, Huanhuan Wei, Wei Mo, Min Yu, 2017