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Lin-Ya You
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Neurodevelopment
Acetylation
Regulation
Diseases
Human Brain
Brain Bank
Cell Atlas
Mapping
Synaptic Transmission
Memory
Areas of Focus
- Acetylation regulation in neurodevelopment and related diseases
- Human brain bank construction and human brain cell atlas mapping
Work Experience
- 2007.07—2010.08 - Hangzhou Sixth People's Hospital - Pharmacist
- 2015.10—2016.12 - Stanford University School of Medicine - Postdoctoral Fellow in Neurosurgery
- 2017.02—Present - Fudan University - Researcher in the Department of Human Anatomy and Histology
Academic Background & Achievements
- 2001.09—2005.07 Bachelor's in Pharmaceutical Engineering: Zhejiang University of Technology
- 2005.09—2007.07 Master's in Pharmaceutical Analysis: Zhejiang University
- 2010.08—2015.08 Ph.D. in Experimental Medicine: McGill University
Publications
- Deficiency of intellectual disability-related gene Brpf1 attenuated hippocampal excitatory synaptic transmission and impaired spatial learning and memory ability, Xian W, Cao J, Yuan X, Wang G, Jin Q, Zhang H, Zhou G, You L, 2021
- Deficiency of intellectual disability-related gene Brpf1 reduced inhibitory neurotransmission in MGE-derived GABAergic interneurons, Cao J, Xian W, Palihati M, Zhu Y, Wang G, Xie Y, Zhou G, You L, 2021
- BRPF1 is essential for development of fetal hematopoietic stem cells, You L, Li L, Zou J, Yan K, Belle J, Nijnik A, Wang E, Yang XJ, 2016
- The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors, You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, 2015
- Deficiency of the chromatin regulator Brpf1 causes abnormal brain development, You L, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, 2015
- The chromatin regulator Brpf1 regulates embryo development and cell proliferation, You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, 2015
- Expression atlas of multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos, You L, Chen L, Penney J, Miao D, Yang XJ, 2014
- Lysine acetylation: enzymes, bromodomains, and links to different diseases, You L, Nie J, Sun WJ, Zheng ZQ, Yang XJ, 2012
- PCAF lysine acetyltransferase, You L, Yang XJ, 2012
- Quality control analysis of brain tissue samples from the Shanghai Brain Bank, Li Fengjiao, Xian Weiwei, Bu Shulei, Cao Jingli, Wu Jinsong, Li Wensheng, You Lin-Ya, 2021
Awards
- 2021: Shanghai Youth Talent Program, Shanghai Science and Technology Commission
- 2019: 'Excellence 2025' Outstanding Talent Program, Fudan University
