Professor | Youhua Xie | Asia Growth Partners

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Name

Youhua Xie

Contact Information

nyhxie@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	Bachelor's Degree in Genetics and Genetic Engineering: Fudan University Ph.D. in Biochemistry: Shanghai Institute of Biochemistry, Chinese Academy of Sciences
Work Experience	Deputy Researcher, Researcher: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Executive Deputy Director, Researcher: Key Laboratory of Medical Molecular Virology, Fudan University Director: Department of Pathogenic Biology, School of Basic Medical Sciences Deputy Director: Shanghai Institute of Major Infectious Diseases and Biosafety
Awards	Shanghai Natural Science Award First Prize (Third) Ministry of Education Natural Science Award First Prize (Fourth)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Bachelor's Degree in Genetics and Genetic Engineering: Fudan University
Ph.D. in Biochemistry: Shanghai Institute of Biochemistry, Chinese Academy of Sciences

Work Experience

Deputy Researcher, Researcher: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Executive Deputy Director, Researcher: Key Laboratory of Medical Molecular Virology, Fudan University
Director: Department of Pathogenic Biology, School of Basic Medical Sciences
Deputy Director: Shanghai Institute of Major Infectious Diseases and Biosafety

Awards

Areas of Focus	Hepatitis B virus infection and antiviral drugs Emerging infectious diseases and antiviral drugs
Publications	High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein, Shen Z, Wu J, Gao Z, Zhang S, Chen J, He J, Guo Y, Deng Q, Xie Y, Liu J, Zhang J, 2022 Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2, Gu CJ, Wu Y, Guo HM, Zhu YF, Xu W, Wang YY, Zhou Y, Sun ZP, Cai X, Li YT, Liu J, Huang Z, Yuan ZH, Zhang R, Deng Q, Qu D, Xie Y, 2021 Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2, Gu Y, Cao J, Zhang X, Gao H, Wang Y, Wang J, He J, Jiang X, Zhang J, Shen G, Yang J, Zheng X, Hu G, Zhu Y, Du S, Zhu Y, Zhang R, Xu J, Lan F, Qu D, Xu G, Zhao Y, Gao D, Xie Y, Luo M, Lu Z, 2021 Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections, Zhang C, Wang YF, Zhu YF, Liu CX, Gu CJ, Xu SQ, Wang YL, Zhou Y, Wang YX, Han WY, Hong XY, Yang Y, Zhang XY, Wang TF, Xu C, Hong Q, Wang ST, Zhao QY, Qiao WH, Zang JK, Kong LL, Wang FF, Wang HK, Qu D, Lavillette D, Tang H, Deng Q, Xie YH, Cong Y, Huang Z, 2021 Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance, Shen ZL, Yang HJ, Yang SS, Wang W, Cui XX, Zhou X, Liu W, Pan SK, Liu YF, Zhang JQ, Zhang JM, Xie YH, Liu J*, 2017

Areas of Focus

Hepatitis B virus infection and antiviral drugs
Emerging infectious diseases and antiviral drugs

Publications

High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein, Shen Z, Wu J, Gao Z, Zhang S, Chen J, He J, Guo Y, Deng Q, Xie Y*, Liu J*, Zhang J*, 2022
Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2, Gu CJ, Wu Y, Guo HM, Zhu YF, Xu W, Wang YY, Zhou Y, Sun ZP, Cai X, Li YT, Liu J, Huang Z, Yuan ZH, Zhang R, Deng Q*, Qu D*, Xie Y*, 2021
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2, Gu Y, Cao J, Zhang X, Gao H, Wang Y, Wang J, He J, Jiang X, Zhang J, Shen G, Yang J, Zheng X, Hu G, Zhu Y, Du S, Zhu Y, Zhang R, Xu J, Lan F, Qu D, Xu G, Zhao Y*, Gao D*, Xie Y*, Luo M*, Lu Z*, 2021
Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections, Zhang C, Wang YF, Zhu YF, Liu CX, Gu CJ, Xu SQ, Wang YL, Zhou Y, Wang YX, Han WY, Hong XY, Yang Y, Zhang XY, Wang TF, Xu C, Hong Q, Wang ST, Zhao QY, Qiao WH, Zang JK, Kong LL, Wang FF, Wang HK, Qu D, Lavillette D, Tang H, Deng Q*, Xie YH*, Cong Y*, Huang Z*, 2021
Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance, Shen ZL, Yang HJ, Yang SS, Wang W, Cui XX, Zhou X, Liu W, Pan SK, Liu YF, Zhang JQ, Zhang JM, Xie YH*, Liu J*, 2017

Hepatitis B Virus Infection Antiviral Drugs Emerging Infectious Diseases Research Virology

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