Professor | Dianwen Ju | Asia Growth Partners

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Name	Dianwen Ju
Contact Information	dianwenju@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Dianwen Ju

Contact Information

dianwenju@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1986.09 – 1991.07 Bachelor in Pharmacy: Second Military Medical University 1991.09 – 1994.07 Master in Pharmacology: Second Military Medical University 1996.09 – 1999.07 PhD in Medical Immunology: Second Military Medical University Shanghai Science and Technology Star Outstanding Discipline Leader in Shanghai
Work Experience	1994 - Present - Second Military Medical University - Assistant and Lecturer Not mentioned - NIH - Visiting Scholar Not mentioned - MediPharm - Researcher Not mentioned - Fudan University - Professor

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1986.09 – 1991.07 Bachelor in Pharmacy: Second Military Medical University
1991.09 – 1994.07 Master in Pharmacology: Second Military Medical University
1996.09 – 1999.07 PhD in Medical Immunology: Second Military Medical University
Shanghai Science and Technology Star
Outstanding Discipline Leader in Shanghai

Work Experience

1994 - Present - Second Military Medical University - Assistant and Lecturer
Not mentioned - NIH - Visiting Scholar
Not mentioned - MediPharm - Researcher
Not mentioned - Fudan University - Professor

Areas of Focus	Research and development of immunotherapeutic drugs such as monoclonal antibodies and cytokines Immunotherapy and gene therapy research for tumors and cardiovascular diseases Targeted nano-drug delivery research for biotechnological drugs
Publications	Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer, Zhang X, Wang Y, Fan J, Chen W, Luan J, Mei X, Wang S, Li Y, Ye L, Li S, Tian W, Yin K, Ju D, 2019 GSDMD membrane pore is critical for IL-1β release and antagonizing IL-1β by hepatocyte-specific nanobiologics is a promising therapeutics for murine alcoholic steatohepatitis, Luan J, Chen W, Fan J, Wang S, Zhang X, Zai W, Jin X, Wang Y, Feng Z, Zhang J, Liu ML, Ju D, 2020 Targeted Interleukin-22 Gene Delivery in the Liver by Poly-Metformin and Penetratin-Based Hybrid Nanoparticles to Treat Non-Alcoholic Fatty Liver Disease, Zai W, Chen W, Wu Z, Jin X, Fan J, Zhang X, Luan J, Tang S, Mei X, Hao Q, Liu H, Ju D, 2019 In vivo hepatocellular expression of interleukin-22 using penetratin-based hybrid nanoparticles as potential anti-hepatitis therapeutics, Chen W, Luan J, Wei G, Zhang X, Fan J, Zai W, Wang S, Wang Y, Liang Y, Nan Y, Yin C, Li Y, Liu ML, Ju D, 2018 Mesoporous silica nanoparticles induced hepatotoxicity via NLRP3 inflammasome activation and caspase-1-dependent pyroptosis, Zhang X, Luan J, Chen W, Fan J, Nan Y, Wang Y, Liang Y, Meng G, Ju D, 2018 Liver-targeted therapy of acetaminophen-induced acute liver injury by interleukin-22 tethered to apolipoprotein A-I, Chen W, Zhang X, Fan J, Zai W, Luan J, Li Y, Wang S, Chen Q, Wang Y, Liang Y, Ju D, 2017 Targeting CD47 and autophagy enhanced anti-tumor effects in non-small cell lung cancer, Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, Luan J, Wang Z, Song P, Chen Q, Tian W, Ju D, 2017 Inhibition of autophagy overcomes the nanotoxicity elicited by Cadmium-based Quantum Dots, Fan J, Sun Y, Wang S, Li Y, Zeng X, Cao Z, Yang P, Song P, Wang Z, Xian Z, Gao H, Chen Q, Cui D, Ju D, 2016 Targeting hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL positive chronic myeloid leukemia, Zeng X, Zhao H, Li Y, Fan J, Sun Y, Wang Z, Wang S, Song P, Ju D, 2015 Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death, Li Y, Zhu H, Wang S, Qian X, Fan J, Wang Z, Song P, Zhang X, Lu W, Ju D, 2015 Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity, Li Y, Zeng X, Wang S, Sun Y, Wang Z, Fan J, Song P, Ju D, 2015 The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers, Wang S, Li Y, Fan J, Wang Z, Zeng X, Sun Y, Song P, Ju D, 2014 Long-term biodistribution in vivo and toxicity of radioactive/magnetic hydroxyapatite nanorods, Liu Y, Sun Y, Cao C, Yang Y, Wu Y, Ju D, Li F, 2014 Pivotal study of iodine-131-labeled chimeric tumor necrosis treatment radioimmunotherapy in patients with advanced lung cancer, Chen S, Yu L, Jiang C, Zhao Y, Sun D, Li S, Liao G, Chen Y, Fu Q, Tao Q, Ye D, Hu P, Khawli LA, Taylor CR, Epstein AL, Ju D, 2005 Interleukin 18 transfection enhances anti-tumor immunity induced by dendritic cell-tumor cell conjugates, Ju D, Yang Y, Lou GL, Tao Q, He L, Cao X, 2001

Areas of Focus

Research and development of immunotherapeutic drugs such as monoclonal antibodies and cytokines
Immunotherapy and gene therapy research for tumors and cardiovascular diseases
Targeted nano-drug delivery research for biotechnological drugs

Publications

Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer, Zhang X, Wang Y, Fan J, Chen W, Luan J, Mei X, Wang S, Li Y, Ye L, Li S, Tian W, Yin K, Ju D, 2019
GSDMD membrane pore is critical for IL-1β release and antagonizing IL-1β by hepatocyte-specific nanobiologics is a promising therapeutics for murine alcoholic steatohepatitis, Luan J, Chen W, Fan J, Wang S, Zhang X, Zai W, Jin X, Wang Y, Feng Z, Zhang J, Liu ML, Ju D, 2020
Targeted Interleukin-22 Gene Delivery in the Liver by Poly-Metformin and Penetratin-Based Hybrid Nanoparticles to Treat Non-Alcoholic Fatty Liver Disease, Zai W, Chen W, Wu Z, Jin X, Fan J, Zhang X, Luan J, Tang S, Mei X, Hao Q, Liu H, Ju D, 2019
In vivo hepatocellular expression of interleukin-22 using penetratin-based hybrid nanoparticles as potential anti-hepatitis therapeutics, Chen W, Luan J, Wei G, Zhang X, Fan J, Zai W, Wang S, Wang Y, Liang Y, Nan Y, Yin C, Li Y, Liu ML, Ju D, 2018
Mesoporous silica nanoparticles induced hepatotoxicity via NLRP3 inflammasome activation and caspase-1-dependent pyroptosis, Zhang X, Luan J, Chen W, Fan J, Nan Y, Wang Y, Liang Y, Meng G, Ju D, 2018
Liver-targeted therapy of acetaminophen-induced acute liver injury by interleukin-22 tethered to apolipoprotein A-I, Chen W, Zhang X, Fan J, Zai W, Luan J, Li Y, Wang S, Chen Q, Wang Y, Liang Y, Ju D, 2017
Targeting CD47 and autophagy enhanced anti-tumor effects in non-small cell lung cancer, Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, Luan J, Wang Z, Song P, Chen Q, Tian W, Ju D, 2017
Inhibition of autophagy overcomes the nanotoxicity elicited by Cadmium-based Quantum Dots, Fan J, Sun Y, Wang S, Li Y, Zeng X, Cao Z, Yang P, Song P, Wang Z, Xian Z, Gao H, Chen Q, Cui D, Ju D, 2016
Targeting hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL positive chronic myeloid leukemia, Zeng X, Zhao H, Li Y, Fan J, Sun Y, Wang Z, Wang S, Song P, Ju D, 2015
Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death, Li Y, Zhu H, Wang S, Qian X, Fan J, Wang Z, Song P, Zhang X, Lu W, Ju D, 2015
Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity, Li Y, Zeng X, Wang S, Sun Y, Wang Z, Fan J, Song P, Ju D, 2015
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers, Wang S, Li Y, Fan J, Wang Z, Zeng X, Sun Y, Song P, Ju D, 2014
Long-term biodistribution in vivo and toxicity of radioactive/magnetic hydroxyapatite nanorods, Liu Y, Sun Y, Cao C, Yang Y, Wu Y, Ju D, Li F, 2014
Pivotal study of iodine-131-labeled chimeric tumor necrosis treatment radioimmunotherapy in patients with advanced lung cancer, Chen S, Yu L, Jiang C, Zhao Y, Sun D, Li S, Liao G, Chen Y, Fu Q, Tao Q, Ye D, Hu P, Khawli LA, Taylor CR, Epstein AL, Ju D, 2005
Interleukin 18 transfection enhances anti-tumor immunity induced by dendritic cell-tumor cell conjugates, Ju D, Yang Y, Lou GL, Tao Q, He L, Cao X, 2001

Monoclonal Antibodies Cytokines Immunotherapy Gene Therapy Tumors Cardiovascular Diseases Nano-Drug Delivery Biotechnology Research Development

Jianzhong Lu - Fudan University

Shuqing Chen - Zhejiang University

Li Qiang Pan - Zhejiang University

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