Professor | Xianyi Sha | Asia Growth Partners

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Name	Xianyi Sha
Contact Information	shaxy@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Xianyi Sha

Contact Information

shaxy@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1995.09 – 1999.07 Bachelor in Pharmacy: Xinjiang Medical University 1999.09 – 2002.07 Master in Pharmaceutics: Xinjiang Medical University 2002.09 – 2005.06 PhD in Pharmaceutics: Fudan University
Work Experience	2005.07 – 2009.12 Lecturer, School of Pharmacy, Fudan University 2007.02 – 2008.08 Postdoctoral Researcher, Karmanos Cancer Institute, USA 2009.12 – 2017.11 Associate Professor, School of Pharmacy, Fudan University 2016.01 – Present Doctoral Supervisor, School of Pharmacy, Fudan University 2017.12 – Present Professor, School of Pharmacy, Fudan University
Awards	Sanofi Young Biological Drug Award (2015.12): China Pharmaceutical Association Shanghai Pharmaceutical Science and Technology Award Second Prize (2005.12) Shanghai Youth Science and Technology Star (2010.05)

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1995.09 – 1999.07 Bachelor in Pharmacy: Xinjiang Medical University
1999.09 – 2002.07 Master in Pharmaceutics: Xinjiang Medical University
2002.09 – 2005.06 PhD in Pharmaceutics: Fudan University

Work Experience

2005.07 – 2009.12 Lecturer, School of Pharmacy, Fudan University
2007.02 – 2008.08 Postdoctoral Researcher, Karmanos Cancer Institute, USA
2009.12 – 2017.11 Associate Professor, School of Pharmacy, Fudan University
2016.01 – Present Doctoral Supervisor, School of Pharmacy, Fudan University
2017.12 – Present Professor, School of Pharmacy, Fudan University

Awards

Sanofi Young Biological Drug Award (2015.12): China Pharmaceutical Association
Shanghai Pharmaceutical Science and Technology Award Second Prize (2005.12)
Shanghai Youth Science and Technology Star (2010.05)

Areas of Focus	Construction and evaluation of novel nano delivery systems Biopharmaceutical evaluation of drugs in vivo Research on new formulations of traditional Chinese medicine
Publications	Red blood cell membrane camouflaged magnetic nanoclusters for imaging-guided photothermal therapy, Ren Xiaoqing, Zheng Rui, Fang Xiaoling, Yang Wuli, Sha Xianyi, 2016 Size-Shifting Micelle Nanoclusters Based on a Cross-Linked and pH-Sensitive Framework for Enhanced Tumor Targeting and Deep Penetration Features, Liang Huihui, Ren Xiaoqing, Qian Jianghui, Zhang Xiulei, Meng Lin, Wang Xiaofei, Li Lei, Fang Xiaoling, Sha Xianyi, 2016 Factors influencing the transfection efficiency and cellular uptake mechanisms of Pluronic P123-modified polypropyleneimine/pDNA polyplexes in multidrug resistant breast cancer cells, Gu Jijin, Hao Junguo, Fang Xiaoling, Sha Xianyi, 2016 CD44-Targeted Hyaluronic Acid-Coated Redox-Responsive Hyperbranched Poly(amido amine)/Plasmid DNA Ternary Nanoassemblies for Efficient Gene Delivery, Gu Jijin, Chen Xinyi, Ren Xiaoqing, Zhang Xiulei, Fang Xiaoling, Sha Xianyi, 2016 Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation, Zhang Xiaoyan, Wang Xiaofei, Zhong Weitong, Ren Xiaoqing, Sha Xianyi, Fang Xiaoling, 2016 Reversal of P-glycoprotein-mediated multidrug resistance by CD44 antibody-targeted nanocomplexes for short hairpin RNA-encoding plasmid DNA delivery, Gu J, Hao J, Fang X, Sha X, 2015 Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly, Fan Z, Chen C, Pang X, Yu Z, Qi Y, Chen X, Liang H, Sha XY, 2015 Serum-resistant complex nanoparticles functionalized with imidazole-rich polypeptide for gene delivery to pulmonary metastatic melanoma, Gu J, Chen X, Xin H, Fang X, Sha X, 2014 In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation, Chen Y, Yang W, Chang B, Hu H, Fang X, Sha X, 2013 Enhanced antitumor efficacy by methotrexate conjugated Pluronic mixed micelles against KBv multidrug resistant cancer, Chen Y, Zhang W, Gu J, Ren Q, Fan Z, Zhong W, Fang X, Sha X, 2013 A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: Enhancing the secretion of chylomicrons, Zhuoyang Fan, Xianyi Sha, 2013 Self-assembled carboxymethyl poly (L-histidine) coated poly (β-amino ester)/DNA complexes for gene transfection, Gu Jijin, Wang Xiao, Fang Xiaoling, Sha Xianyi, 2012

Areas of Focus

Construction and evaluation of novel nano delivery systems
Biopharmaceutical evaluation of drugs in vivo
Research on new formulations of traditional Chinese medicine

Publications

Red blood cell membrane camouflaged magnetic nanoclusters for imaging-guided photothermal therapy, Ren Xiaoqing, Zheng Rui, Fang Xiaoling, Yang Wuli, Sha Xianyi, 2016
Size-Shifting Micelle Nanoclusters Based on a Cross-Linked and pH-Sensitive Framework for Enhanced Tumor Targeting and Deep Penetration Features, Liang Huihui, Ren Xiaoqing, Qian Jianghui, Zhang Xiulei, Meng Lin, Wang Xiaofei, Li Lei, Fang Xiaoling, Sha Xianyi, 2016
Factors influencing the transfection efficiency and cellular uptake mechanisms of Pluronic P123-modified polypropyleneimine/pDNA polyplexes in multidrug resistant breast cancer cells, Gu Jijin, Hao Junguo, Fang Xiaoling, Sha Xianyi, 2016
CD44-Targeted Hyaluronic Acid-Coated Redox-Responsive Hyperbranched Poly(amido amine)/Plasmid DNA Ternary Nanoassemblies for Efficient Gene Delivery, Gu Jijin, Chen Xinyi, Ren Xiaoqing, Zhang Xiulei, Fang Xiaoling, Sha Xianyi, 2016
Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation, Zhang Xiaoyan, Wang Xiaofei, Zhong Weitong, Ren Xiaoqing, Sha Xianyi, Fang Xiaoling, 2016
Reversal of P-glycoprotein-mediated multidrug resistance by CD44 antibody-targeted nanocomplexes for short hairpin RNA-encoding plasmid DNA delivery, Gu J, Hao J, Fang X, Sha X, 2015
Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly, Fan Z, Chen C, Pang X, Yu Z, Qi Y, Chen X, Liang H, Sha XY, 2015
Serum-resistant complex nanoparticles functionalized with imidazole-rich polypeptide for gene delivery to pulmonary metastatic melanoma, Gu J, Chen X, Xin H, Fang X, Sha X, 2014
In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation, Chen Y, Yang W, Chang B, Hu H, Fang X, Sha X, 2013
Enhanced antitumor efficacy by methotrexate conjugated Pluronic mixed micelles against KBv multidrug resistant cancer, Chen Y, Zhang W, Gu J, Ren Q, Fan Z, Zhong W, Fang X, Sha X, 2013
A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: Enhancing the secretion of chylomicrons, Zhuoyang Fan, Xianyi Sha, 2013
Self-assembled carboxymethyl poly (L-histidine) coated poly (β-amino ester)/DNA complexes for gene transfection, Gu Jijin, Wang Xiao, Fang Xiaoling, Sha Xianyi, 2012

Nano Delivery Systems Biopharmaceutical Evaluation Traditional Chinese Medicine Drug Delivery Nanotechnology Polymeric Materials Mdr Reversal Gene Delivery Clinical Translation Caco-2 Cell Model

Qizhi Zhang - Fudan University

Fuqiang Hu - Zhejiang University

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