2000.09 – 2004.07 Ph.D. in Pharmaceutical Chemistry, Fudan University (Shanghai Medical University)
1994.09 - 1997.07 M.Sc. in Pharmaceutical Chemistry, Shanghai Medical University
1983.09 – 1987.06 B.Sc. in Chemistry, Nanchang University
2010.01-present - Fudan University, School of Pharmacy, Department of Natural Medicinal Chemistry - Professor, Doctoral Supervisor
2009.01-2010.01 - Fudan University, School of Pharmacy, Department of Natural Medicinal Chemistry - Professor, Master's Supervisor
2001.01-2010.01 - Fudan University, School of Pharmacy, Department of Natural Medicinal Chemistry - Associate Professor, Master's Supervisor
1997.07-2001.01 - Fudan University, School of Pharmacy, Department of Organic Chemistry - Associate Professor
2017.06-2019.09 - Fudan University, Shanghai Medical College - Vice Dean
2012.12-2017.06 - Fudan University, School of Pharmacy - Vice Dean of Research
2014.12-2015.10 - Fudan University, School of Pharmacy - Acting Dean
2009.01-2012.12 - Fudan University, School of Pharmacy - Vice Dean of Administration
Shanghai Outstanding Academic Leader (2014)
Shanghai Pharmaceutical Association Science and Technology Award Second Prize (2012)
Fudan University March 8th Red Banner Holder
Fudan University School of Pharmacy Dean's Award
Fudan University School of Pharmacy 'My Favorite Teacher'
Research
Optimization and discovery of active natural lead compounds and their functional target mechanisms Validation of potential clinical targets and development of new drugs for anti-tumor, anti-inflammatory immunity, and anti-drug-resistant bacteria Diversity synthesis methodology and total synthesis of natural product advantageous skeleton structures
Discovery of First-in-Class TAK1–MKK3 Protein–Protein Interaction (PPI) Inhibitor (R)-STU104 for the Treatment of Ulcerative Colitis through Modulating TNF-α Production, Mei-Lin Tang, Haidong Li, Jin-Feng Ning, Xiaoyan Shen, Xun Sun, 2022
Discovery of pyrimidine-bridged CA-4 CBSIs for the treatment of cervical cancer in combination with cisplatin with significantly reduced nephrotoxicity, Zhipeng Huo, Kunlin Liu, Xi Zhang, Yongxi Liang, Xun Sun, 2022
Identification, Synthesis, and Comprehension of an Imidazole N-3 Regioisomeric Impurity of Olmesartan Medoxomil Key Intermediate, Jianwu Lu, Xiao Li, Shun Yuan, Yinquan Wang, Han Sun, Weizhao Weng, Yinfei Shi, Xiaoxu Wang, Kongcheng Huang, Xun Sun, Taizhi Wu, 2022
Design, synthesis and biological evaluation of novel 5-methyl-2,4,5,6-tetrahydropyrrolo [3,4-c] pyrazole derivatives as potent potassium-competitive acid blockers, Wang Xianlian, Xu Yongmei, Zong Zaiwei, Cai Jinna, Chen Chunlin, Zhang Qingwei, Sun Xun, Li Jianqi, 2022
A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis, Zheng-Nan Ren, Jun Yang, Meng-Ya Zhang, Yi-Wen Huang, Dong-Xiao Song, Xun Sun, Li-Long Pan, Jia Sun, 2022
A Novel Resveratrol Analog Upregulates SIRT1 Expression and Ameliorates Neointima Formation, Baohui Yuan, He Liu, Xiaoliang Dong, Xiaohua Pan, Xun Sun, Jia Sun, Li-Long Pan, 2021
LMR-101, a novel derivative of propofol, exhibits potent anticonvulsant effects and possibly interacts with a novel target on γ-aminobutyric acid type A receptors, Yi Zhao, Long An, Shupan Guo, Xiaoxing Huang, Huajie Tian, Li Liu, Tao Chen, Xun Sun, Qibing Mei, Rutao Wang, 2021
TMSOTf-mediated approach to 1,3-oxazin-2-one skeleton through one-pot successive reduction-[4 + 2] cyclization process of imides with ynamides, Chen-Chen Zhang, Zhi-Peng Huo, Mei-Lin Tang, Yong-Xi Liang, Xun Sun, 2021
A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring Nε-thioacetyl-lysine, Renwu Lia, Lingling Yan, Xun Sun, Weiping Zheng, 2020
Study on the Total Synthesis of Resveratrol Dimers Quadrangularin A and Pallidol, Ji-lai Han, Mei-Lin Tang, Xun Sun, 2020
A Concise Approach to N-substituted Rhodanines through a Base-assisted One-pot Coupling and Cyclization Process, Yongxi Liang, Mei-Lin Tang, Zhipeng Huo, Chenchen Zhang, Xun Sun, 2020
Novel octapeptide-DTX prodrugs targeting MMP-7 as effective agents for the treatment of colorectal cancer with lower systemic toxicity, Zheng-Yu Liu, Mei-Lin Tang, Jin-Feng Ning, Yun-Peng Hao, Lu Zhou, Xun Sun, 2020
Design, synthesis and biological evaluation of novel indone derivatives as selective ERβ modulators, Xi-Xi Liu, Mei-Lin Tang, Chen Zhong, Yun Tang, Jian-Ming Yu, Xun Sun, 2019
Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis, Yong-Wei Jiang, Liang Xu, Wei Fu, Hua Lin, Jian-Ming Yu, Xun Sun, 2018
Discovery of novel 1,2,3,4-tetrahydrobenzo[4, 5]thieno[2, 3-c]pyridine derivatives as potent and selective CYP17 inhibitors, Mingliang Wang, Yanjia Fang, Shoulai Gu, Fangfang Chen, Zhengjiang Zhu, Xun Sun, Jidong Zhu, 2017
Divergent copper-mediated dimerization and hydroxylation of benzamides involving C–H bond functionalization, Mingliang Wang, Yimin Hu, Zhe Jiang, Hong C. Shen, Xun Sun, 2016
Novel Fluorinated Docetaxel Analogue for Anti-hepatoma：Molecular Docking and Biological Evaluation, Yun-peng Hao, Zheng-yu Liu, Cheng Xie, Lu Zhou, Xun Sun, 2016
