Professor | Jun Chen | Asia Growth Partners

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Name	Jun Chen
Contact Information	chenjun@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jun Chen

Contact Information

chenjun@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1993.09 – 1997.06 Bachelor of Science: Shanghai Medical University, School of Pharmacy 1999.09 – 2005.12 Doctor of Science: Fudan University, School of Pharmacy
Work Experience	1997.07 – 2001.12 - Fudan University, School of Pharmacy, Department of Drug Analysis - Assistant 2002.01 – 2008.11 - Fudan University, School of Pharmacy, Department of Pharmaceutics - Lecturer 2008.12 – 2014.11 - Fudan University, School of Pharmacy, Department of Pharmaceutics - Associate Professor, Master's Supervisor 2014.12 – Present - Fudan University, School of Pharmacy, Department of Pharmaceutics - Professor, Doctoral Supervisor
Awards	New Century Excellent Talents Support Program (2011): Ministry of Education Shiyao Young Pharmaceutics Award (2012): Chinese Pharmaceutical Association Outstanding Master's Thesis Advisor (2014, 2015): Shanghai Second Prize in Science and Technology (2010): Chinese Pharmaceutical Association Merck-Fudan Teaching Award (2011)

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1993.09 – 1997.06 Bachelor of Science: Shanghai Medical University, School of Pharmacy
1999.09 – 2005.12 Doctor of Science: Fudan University, School of Pharmacy

Work Experience

1997.07 – 2001.12 - Fudan University, School of Pharmacy, Department of Drug Analysis - Assistant
2002.01 – 2008.11 - Fudan University, School of Pharmacy, Department of Pharmaceutics - Lecturer
2008.12 – 2014.11 - Fudan University, School of Pharmacy, Department of Pharmaceutics - Associate Professor, Master's Supervisor
2014.12 – Present - Fudan University, School of Pharmacy, Department of Pharmaceutics - Professor, Doctoral Supervisor

Awards

New Century Excellent Talents Support Program (2011): Ministry of Education
Shiyao Young Pharmaceutics Award (2012): Chinese Pharmaceutical Association
Outstanding Master's Thesis Advisor (2014, 2015): Shanghai
Second Prize in Science and Technology (2010): Chinese Pharmaceutical Association
Merck-Fudan Teaching Award (2011)

Areas of Focus	Targeted Drug Delivery Systems Pharmacokinetics and Drugability Evaluation of Drug Formulations Research and Development of New Drug Forms and Formulations
Publications	iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas, Kang Ting, Gao Xiaoling, Hu Quanyin, Jiang Di, Feng Xingye, Zhang Xue, Song Qingxiang, Yao Lei, Huang Meng, Jiang Xinguo, Pang Zhiqing, Chen Hongzhuan, Chen Jun, 2014 Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy, Miao Deyu, Jiang Mengyin, Liu Zhongyang, Gu Guangzhi, Hu Quanyin, Kang Ting, Song Qingxiang, Yao Lei, Li Wei, Gao Xiaoling, Sun Mingjiang, Chen Jun, 2014 PEG-PLA nanoparticles modified with APTEDB peptide for enhanced anti-angiogenic and anti-glioma therapy, Gu Guangzhi, Hu Quanyin, Feng Xingye, Gao Xiaoling, Jiang Menglin, Kang Ting, Jiang Di, Song Qingxiang, Chen Hongzhuan, Chen Jun, 2014 Facilitated brain delivery of poly (ethylene glycol)-poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound, Lei Yao, Qingxiang Song, Wenkun Bai, Jizhen Zhang, Deyu Miao, Mengyin Jiang, Yu Wang, Zhiyong Shen, Quanyin Hu, Xiao Gu, Meng Huang, Gang Zheng, Xiaoling Gao, Bing Hu, Chen Jun, Hongzhuan Chen, 2014 Harnessing the Capacity of Cell-Penetrating Peptides for Drug Delivery to the Central Nervous System, Ting Kang, Xiaoling Gao, Chen Jun, 2014 The influence of the penetrating peptide iRGD on the effect of paclitaxel-loaded MT1-AF7p-conjugated nanoparticles on glioma cells, Gu Guangzhi, Gao Xiaoling, Hu Quanyin, Kang Ting, Liu Zhongyang, Jiang Mengyin, Miao Deyu, Song Qingxiang, Yao Lei, Tu Yifan, Pang Zhiqing, Chen Hongzhuan, Jiang Xinguo, Chen Jun, 2013 Glioma therapy using tumor homing and penetrating peptide functionalized PEG-PLA nanoparticles loaded with paclitaxel, Hu Quanyin, Gao Xiaoling, Gu Guangzhi, Kang Ting, Tu Yifan, Liu Zhongyang, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Hongzhuan, Chen Jun, 2013 CGKRK-modified nanoparticles for dual-targeting drug delivery to tumor cells and angiogenic blood vessels, Hu Quanyin, Gao Xiaoling, Kang Ting, Feng Xingye, Jiang Di, Tu Yifan, Song Qingxiang, Yao Lei, Jiang Xinguo, Chen Hongzhuan, Chen Jun, 2013 PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy, Gu Guangzhi, Xia Huimin, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2013 F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery, Hu Quanyin, Gu Guangzhi, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Xia Huimin, Chen Hongzhuan, Jiang Xinguo, Gao Xiaoling, Chen Jun, 2013 Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Gu Guangzhi, Hu Quanyin, Song Qingxiang, Yao Lei, Tu Yifan, Pang Zhiqing, Chen Hongzhuan, Jiang Xinguo, Gao Xiaoling, Chen Jun, 2013 B6 peptide-modified PEG-PLA nanoparticles for enhanced brain delivery of neuroprotective peptide, Liu Zhongyang, Gao Xiaoling, Kang Ting, Jiang Mengyin, Miao Deyu, Gu Guangzhi, Hu Quanyin, Song Qingxiang, Yao Lei, Tu Yifan, Chen Hongzhuan, Jiang Xinguo, Chen Jun, 2013 Activatable cell penetrating peptide-conjugated nanoparticles with enhanced permeability for site-specific targeting delivery of anticancer drug, Xia Huimin, Gu Guangzhi, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Song Qingxiang, Yao Lei, Tu Yifan, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2013 Cellular internalization pathway and transcellular transport of pegylated polyester nanoparticles in Caco-2 cells, Song Qingxiang, Wang Xiaoling, Hu Quanyin, Huang Meng, Yao Lei, Qi Hong, Qiu Yu, Jiang Xinguo, Chen Jun, Chen Hongzhuan, Gao Xiaoling, 2013 Mechanisms of transcellular transport of wheat germ agglutinin-functionalized polymeric nanoparticles in Caco-2 cells, Song Qingxiang, Yao Lei, Huang Meng, Hu Quanyin, Lu Qing, Wu Bingxian, Qi Hong, Rong Zhengxing, Jiang Xinguo, Gao Xiaoling, Chen Jun, Chen Hongzhuan, 2012 Penetratin-functionalized PEG-PLA nanoparticles for brain drug delivery, Xia Huimin, Gao Xiaoling, Gu Guangzhi, Liu Zhongyang, Hu Quanyin, Tu Yifan, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2012 Lipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorption, Zeng Ni, Gao Xiaoling, Hu Quanyin, Song Qingxiang, Xia Huimin, Liu Zhongyang, Gu Guangzhi, Jiang Mengying, Pang Zhiqing, Chen Hongzhuan, Chen Jun, Fang L, 2012 Preparation and characterization of paclitaxel-loaded DSPE-PEG-liquid crystalline nanoparticles (LCNPs) for improved bioavailability, Zeng Ni, Hu Quanyin, Liu Zhongyang, Gao Xiaoling, Hu Rongkuan, Song Qingxiang, Gu Guangzhi, Xia Huimin, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Fang Liang, 2012 Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery, Guo Jianwei, Gao Xiaoling, Su Lina, Xia Huimin, Gu Guangzhi, Pang Zhiqing, Jiang Xinguo, Yao Lei, Chen Jun, Chen Hongzhuan, 2011 Low molecular weight protamine functionalized nanoparticles for drug delivery to the brain after intranasal administration, Xia Huimin, Gao Xiaoling, Gu Guangzhi, Liu Zhongyang, Zeng Ni, Hu Quanyin, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2011 The association of autophagy with polyethylenimine-induced cytotoxicity in nephritic and hepatic cell lines, Gao Xiaoling, Yao Lei, Song Qingxiang, Zhu Liang, Xia Zheng, Xia Huimin, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2011 Determination of sulphasalazine and its main metabolite sulphapyridine and 5-aminosalicylic acid in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study, Gu Guangzhi, Xia Huimin, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2011 Determination of Fulvestrant in Rat Plasma by LC–MS–MS: Application to a Pharmacokinetic Study, Liu Zhongyang, Gu Guangzhi, Xia Huimin, Liu Qiang, Pang Zhiqing, Jiang Xinguo, Chen Jun, 2011 Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography-tandem mass spectrometry, Xia Huimin, Su Lina, Guo Jianwei, Liu Guangming, Pang Zhiqing, Jiang Xinguo, Chen Jun, 2010 LC determination and pharmacokinetic study of gemfibrozil in human plasma, Su Lina, Guo Jianwei, Liu Guangming, Xia Huimin, Chen Jun, Jiang X, 2010 Follicle-stimulating hormone peptide can facilitate paclitaxel nanoparticles to target ovarian carcinoma in vivo, Zhang Xiaoyan, Chen Jun, Gao Xiaoling, Kang Yu, Xu Congjian, 2009

Areas of Focus

Targeted Drug Delivery Systems
Pharmacokinetics and Drugability Evaluation of Drug Formulations
Research and Development of New Drug Forms and Formulations

Publications

iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas, Kang Ting, Gao Xiaoling, Hu Quanyin, Jiang Di, Feng Xingye, Zhang Xue, Song Qingxiang, Yao Lei, Huang Meng, Jiang Xinguo, Pang Zhiqing, Chen Hongzhuan, Chen Jun, 2014
Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy, Miao Deyu, Jiang Mengyin, Liu Zhongyang, Gu Guangzhi, Hu Quanyin, Kang Ting, Song Qingxiang, Yao Lei, Li Wei, Gao Xiaoling, Sun Mingjiang, Chen Jun, 2014
PEG-PLA nanoparticles modified with APTEDB peptide for enhanced anti-angiogenic and anti-glioma therapy, Gu Guangzhi, Hu Quanyin, Feng Xingye, Gao Xiaoling, Jiang Menglin, Kang Ting, Jiang Di, Song Qingxiang, Chen Hongzhuan, Chen Jun, 2014
Facilitated brain delivery of poly (ethylene glycol)-poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound, Lei Yao, Qingxiang Song, Wenkun Bai, Jizhen Zhang, Deyu Miao, Mengyin Jiang, Yu Wang, Zhiyong Shen, Quanyin Hu, Xiao Gu, Meng Huang, Gang Zheng, Xiaoling Gao, Bing Hu, Chen Jun, Hongzhuan Chen, 2014
Harnessing the Capacity of Cell-Penetrating Peptides for Drug Delivery to the Central Nervous System, Ting Kang, Xiaoling Gao, Chen Jun, 2014
The influence of the penetrating peptide iRGD on the effect of paclitaxel-loaded MT1-AF7p-conjugated nanoparticles on glioma cells, Gu Guangzhi, Gao Xiaoling, Hu Quanyin, Kang Ting, Liu Zhongyang, Jiang Mengyin, Miao Deyu, Song Qingxiang, Yao Lei, Tu Yifan, Pang Zhiqing, Chen Hongzhuan, Jiang Xinguo, Chen Jun, 2013
Glioma therapy using tumor homing and penetrating peptide functionalized PEG-PLA nanoparticles loaded with paclitaxel, Hu Quanyin, Gao Xiaoling, Gu Guangzhi, Kang Ting, Tu Yifan, Liu Zhongyang, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Hongzhuan, Chen Jun, 2013
CGKRK-modified nanoparticles for dual-targeting drug delivery to tumor cells and angiogenic blood vessels, Hu Quanyin, Gao Xiaoling, Kang Ting, Feng Xingye, Jiang Di, Tu Yifan, Song Qingxiang, Yao Lei, Jiang Xinguo, Chen Hongzhuan, Chen Jun, 2013
PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy, Gu Guangzhi, Xia Huimin, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2013
F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery, Hu Quanyin, Gu Guangzhi, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Xia Huimin, Chen Hongzhuan, Jiang Xinguo, Gao Xiaoling, Chen Jun, 2013
Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Gu Guangzhi, Hu Quanyin, Song Qingxiang, Yao Lei, Tu Yifan, Pang Zhiqing, Chen Hongzhuan, Jiang Xinguo, Gao Xiaoling, Chen Jun, 2013
B6 peptide-modified PEG-PLA nanoparticles for enhanced brain delivery of neuroprotective peptide, Liu Zhongyang, Gao Xiaoling, Kang Ting, Jiang Mengyin, Miao Deyu, Gu Guangzhi, Hu Quanyin, Song Qingxiang, Yao Lei, Tu Yifan, Chen Hongzhuan, Jiang Xinguo, Chen Jun, 2013
Activatable cell penetrating peptide-conjugated nanoparticles with enhanced permeability for site-specific targeting delivery of anticancer drug, Xia Huimin, Gu Guangzhi, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Song Qingxiang, Yao Lei, Tu Yifan, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2013
Cellular internalization pathway and transcellular transport of pegylated polyester nanoparticles in Caco-2 cells, Song Qingxiang, Wang Xiaoling, Hu Quanyin, Huang Meng, Yao Lei, Qi Hong, Qiu Yu, Jiang Xinguo, Chen Jun, Chen Hongzhuan, Gao Xiaoling, 2013
Mechanisms of transcellular transport of wheat germ agglutinin-functionalized polymeric nanoparticles in Caco-2 cells, Song Qingxiang, Yao Lei, Huang Meng, Hu Quanyin, Lu Qing, Wu Bingxian, Qi Hong, Rong Zhengxing, Jiang Xinguo, Gao Xiaoling, Chen Jun, Chen Hongzhuan, 2012
Penetratin-functionalized PEG-PLA nanoparticles for brain drug delivery, Xia Huimin, Gao Xiaoling, Gu Guangzhi, Liu Zhongyang, Hu Quanyin, Tu Yifan, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2012
Lipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorption, Zeng Ni, Gao Xiaoling, Hu Quanyin, Song Qingxiang, Xia Huimin, Liu Zhongyang, Gu Guangzhi, Jiang Mengying, Pang Zhiqing, Chen Hongzhuan, Chen Jun, Fang L, 2012
Preparation and characterization of paclitaxel-loaded DSPE-PEG-liquid crystalline nanoparticles (LCNPs) for improved bioavailability, Zeng Ni, Hu Quanyin, Liu Zhongyang, Gao Xiaoling, Hu Rongkuan, Song Qingxiang, Gu Guangzhi, Xia Huimin, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Fang Liang, 2012
Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery, Guo Jianwei, Gao Xiaoling, Su Lina, Xia Huimin, Gu Guangzhi, Pang Zhiqing, Jiang Xinguo, Yao Lei, Chen Jun, Chen Hongzhuan, 2011
Low molecular weight protamine functionalized nanoparticles for drug delivery to the brain after intranasal administration, Xia Huimin, Gao Xiaoling, Gu Guangzhi, Liu Zhongyang, Zeng Ni, Hu Quanyin, Song Qingxiang, Yao Lei, Pang Zhiqing, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2011
The association of autophagy with polyethylenimine-induced cytotoxicity in nephritic and hepatic cell lines, Gao Xiaoling, Yao Lei, Song Qingxiang, Zhu Liang, Xia Zheng, Xia Huimin, Jiang Xinguo, Chen Jun, Chen Hongzhuan, 2011
Determination of sulphasalazine and its main metabolite sulphapyridine and 5-aminosalicylic acid in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study, Gu Guangzhi, Xia Huimin, Hu Quanyin, Liu Zhongyang, Jiang Mengyin, Kang Ting, Miao Deyu, Tu Yifan, Pang Zhiqing, Song Qingxiang, Yao Lei, Chen Hongzhuan, Gao Xiaoling, Chen Jun, 2011
Determination of Fulvestrant in Rat Plasma by LC–MS–MS: Application to a Pharmacokinetic Study, Liu Zhongyang, Gu Guangzhi, Xia Huimin, Liu Qiang, Pang Zhiqing, Jiang Xinguo, Chen Jun, 2011
Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography-tandem mass spectrometry, Xia Huimin, Su Lina, Guo Jianwei, Liu Guangming, Pang Zhiqing, Jiang Xinguo, Chen Jun, 2010
LC determination and pharmacokinetic study of gemfibrozil in human plasma, Su Lina, Guo Jianwei, Liu Guangming, Xia Huimin, Chen Jun, Jiang X, 2010
Follicle-stimulating hormone peptide can facilitate paclitaxel nanoparticles to target ovarian carcinoma in vivo, Zhang Xiaoyan, Chen Jun, Gao Xiaoling, Kang Yu, Xu Congjian, 2009

Targeted Drug Delivery Nanoparticles Pharmacokinetics Drug Formulations Tumor Targeting Peptides Brain Targeting Alzheimer'S Disease Chemotherapy Nanomedicine

Jiang Xinguo - Fudan University

Zhijing Pang - Fudan University

Ying Xie - Peking University

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