Professor | Zezhong Liu | Asia Growth Partners

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Name	Zezhong Liu
Contact Information	zezhongliu@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Zezhong Liu

Contact Information

zezhongliu@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2017.09 – 2020.08 PhD: Fudan University, Pathogen Biology 2014.09 – 2017.07 Master's: Chinese Academy of Agricultural Sciences, Preventive Veterinary Medicine 2009.09 – 2014.07 Bachelor's: Northwest A&F University, Veterinary Medicine
Work Experience	2022.09 - Present - Fudan University, School of Pharmacy - Junior Researcher 2020.09 - 2022.08 - Fudan University, School of Basic Medical Sciences - Postdoctoral Researcher
Awards	2023: National Youth Talent Program 2023: Shanghai Youth Science and Technology Star

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2017.09 – 2020.08 PhD: Fudan University, Pathogen Biology
2014.09 – 2017.07 Master's: Chinese Academy of Agricultural Sciences, Preventive Veterinary Medicine
2009.09 – 2014.07 Bachelor's: Northwest A&F University, Veterinary Medicine

Work Experience

2022.09 - Present - Fudan University, School of Pharmacy - Junior Researcher
2020.09 - 2022.08 - Fudan University, School of Basic Medical Sciences - Postdoctoral Researcher

Awards

2023: National Youth Talent Program
2023: Shanghai Youth Science and Technology Star

Areas of Focus	Research on prevention strategies for emerging infectious diseases Research on new adjuvants Research on highly efficient broad-spectrum antiviral vaccines (coronavirus/influenza virus/enterovirus) Research on antiviral peptides and antibody drugs
Publications	A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates, Z. Liu, J. Zhou, X. Wang, W. Xu, Z. Teng, H. Chen, M. Chen, G. Zhang, Y. Wang, J. Huang, Q. Wang, S. Jiang, L. Lu, 2023 Up or down: where comes Omicron?, Z. Liu, L. Lu, S. Jiang, 2022 A Pan-sarbecovirus Vaccine Induces Highly Potent and Durable Neutralizing Antibody Responses in Non-human Primates against SARS-CoV-2 Omicron Variant, Z. Liu, JF. Chan, J. Zhou, M. Wang, Q. Wang, G. Zhang, W. Xu, KK. Chik, Y. Zhang, Y. Wang, KY. Yuen, L. Lu, S. Jiang, 2022 A novel STING Agonist-Adjuvanted Pan-Sarbecovirus Vaccine Elicits Potent and Durable Neutralizing Antibody and T Cell Responses in Mice, Rabbits and NHPs, Z. Liu, J. Zhou, W. Xu, W. Deng, Y. Wang, M. Wang, Q. Wang, M. Hsieh, J. Dong, X. Wang, W. Huang, L. Xing, M. He, C. Tao, Y. Xie, Y. Zhang, Y. Wang, J. Zhao, Z. Yuan, C. Qin, S. Jiang, L. Lu, 2022 An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope, Z. Liu, W. Xu, Z. Chen, W. Fu, W. Zhan, Y. Gao, J. Zhou, Y. Zhou, J. Wu, Q. Wang, X. Zhang, A. Hao, W. Wu, Q. Zhang, Y. Li, K. Fan, R. Chen, Q. Jiang, CT. Mayer, T. Schoofs, Y. Xie, S. Jiang, Y. Wen, Z. Yuan, K. Wang, L. Lu, L. Sun, Q. Wang, 2022 Inhibition of viral suppressor of RNAi proteins by designer peptides protects from enteroviral infection in vivo, Y. Fang, Z. Liu, Y. Qiu, J. Kong, Y. Fu, Y. Liu, C. Wang, J. Quan, Q. Wang, W. Xu, L. Yin, J. Cui, Y. Xu, S. Curry, S. Jiang, L. Lu, X. Zhou, 2021 RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response, Z. Liu, W. Xu, S. Xia, C. Gu, X. Wang, Q. Wang, J. Zhou, Y. Wu, X. Cai, D. Qu, T. Ying, Y. Xie, L. Lu, Z. Yuan, S. Jiang, 2020 A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases, J. Zhou, W. Xu, Z. Liu, C. Wang, S. Xia, Q. Lan, Y. Cai, S. Su, J. Pu, L. Xing, Y. Xie, L. Lu, S. Jiang, Q. Wang, 2022 Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD, Y. Zhou, Z. Liu, S. Li, W. Xu, Q. Zhang, IT. Silva, C. Li, Y. Wu, Q. Jiang, Z. Liu, Q. Wang, Y. Guo, J. Wu, C. Gu, X. Cai, D. Qu, CT. Mayer, X. Wang, S. Jiang, T. Ying, Z. Yuan, Y. Xie, Y. Wen, L. Lu, Q. Wang, 2021 Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell, Z. Liu, S. Xia, X. Wang, Q. Lan, P. Li, W. Xu, Q. Wang, L. Lu, S. Jiang, 2020 Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta Variant, N. Zhang, Q. Ji, Z. Liu, K. Tang, Y. Xie, K. Li, J. Zhou, S. Li, H. Shang, Z. Shi, T. Zheng, J. Yao, L. Lu, S. Yuan, S. Jiang, 2022 Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection, Z. Liu, S. Xia, X. Wang, Q. Lan, W. Xu, Q. Wang, S. Jiang, L. Lu, 2020 Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus, Z. Liu, J. Shao, F. Zhao, G. Zhou, S. Gao, W. Liu, J. Lv, X. Li, Y. Li, H. Chang, Y. Zhang, 2017

Areas of Focus

Research on prevention strategies for emerging infectious diseases
Research on new adjuvants
Research on highly efficient broad-spectrum antiviral vaccines (coronavirus/influenza virus/enterovirus)
Research on antiviral peptides and antibody drugs

Publications

A pan-sarbecovirus vaccine based on RBD of SARS-CoV-2 original strain elicits potent neutralizing antibodies against XBB in non-human primates, Z. Liu, J. Zhou, X. Wang, W. Xu, Z. Teng, H. Chen, M. Chen, G. Zhang, Y. Wang, J. Huang, Q. Wang, S. Jiang, L. Lu, 2023
Up or down: where comes Omicron?, Z. Liu, L. Lu, S. Jiang, 2022
A Pan-sarbecovirus Vaccine Induces Highly Potent and Durable Neutralizing Antibody Responses in Non-human Primates against SARS-CoV-2 Omicron Variant, Z. Liu, JF. Chan, J. Zhou, M. Wang, Q. Wang, G. Zhang, W. Xu, KK. Chik, Y. Zhang, Y. Wang, KY. Yuen, L. Lu, S. Jiang, 2022
A novel STING Agonist-Adjuvanted Pan-Sarbecovirus Vaccine Elicits Potent and Durable Neutralizing Antibody and T Cell Responses in Mice, Rabbits and NHPs, Z. Liu, J. Zhou, W. Xu, W. Deng, Y. Wang, M. Wang, Q. Wang, M. Hsieh, J. Dong, X. Wang, W. Huang, L. Xing, M. He, C. Tao, Y. Xie, Y. Zhang, Y. Wang, J. Zhao, Z. Yuan, C. Qin, S. Jiang, L. Lu, 2022
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope, Z. Liu, W. Xu, Z. Chen, W. Fu, W. Zhan, Y. Gao, J. Zhou, Y. Zhou, J. Wu, Q. Wang, X. Zhang, A. Hao, W. Wu, Q. Zhang, Y. Li, K. Fan, R. Chen, Q. Jiang, CT. Mayer, T. Schoofs, Y. Xie, S. Jiang, Y. Wen, Z. Yuan, K. Wang, L. Lu, L. Sun, Q. Wang, 2022
Inhibition of viral suppressor of RNAi proteins by designer peptides protects from enteroviral infection in vivo, Y. Fang, Z. Liu, Y. Qiu, J. Kong, Y. Fu, Y. Liu, C. Wang, J. Quan, Q. Wang, W. Xu, L. Yin, J. Cui, Y. Xu, S. Curry, S. Jiang, L. Lu, X. Zhou, 2021
RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response, Z. Liu, W. Xu, S. Xia, C. Gu, X. Wang, Q. Wang, J. Zhou, Y. Wu, X. Cai, D. Qu, T. Ying, Y. Xie, L. Lu, Z. Yuan, S. Jiang, 2020
A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases, J. Zhou, W. Xu, Z. Liu, C. Wang, S. Xia, Q. Lan, Y. Cai, S. Su, J. Pu, L. Xing, Y. Xie, L. Lu, S. Jiang, Q. Wang, 2022
Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD, Y. Zhou, Z. Liu, S. Li, W. Xu, Q. Zhang, IT. Silva, C. Li, Y. Wu, Q. Jiang, Z. Liu, Q. Wang, Y. Guo, J. Wu, C. Gu, X. Cai, D. Qu, CT. Mayer, X. Wang, S. Jiang, T. Ying, Z. Yuan, Y. Xie, Y. Wen, L. Lu, Q. Wang, 2021
Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell, Z. Liu, S. Xia, X. Wang, Q. Lan, P. Li, W. Xu, Q. Wang, L. Lu, S. Jiang, 2020
Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta Variant, N. Zhang, Q. Ji, Z. Liu, K. Tang, Y. Xie, K. Li, J. Zhou, S. Li, H. Shang, Z. Shi, T. Zheng, J. Yao, L. Lu, S. Yuan, S. Jiang, 2022
Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection, Z. Liu, S. Xia, X. Wang, Q. Lan, W. Xu, Q. Wang, S. Jiang, L. Lu, 2020
Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus, Z. Liu, J. Shao, F. Zhao, G. Zhou, S. Gao, W. Liu, J. Lv, X. Li, Y. Li, H. Chang, Y. Zhang, 2017

Infectious Diseases Prevention Adjuvants Vaccines Coronavirus Influenza Enterovirus Antiviral Peptides Antibodies

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