Professor | Haiyan Zhu | Asia Growth Partners

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Name	Haiyan Zhu
Contact Information	haiyanzhu@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Haiyan Zhu

Contact Information

haiyanzhu@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1991.09 – 2002.07 Bachelor's, Master's, PhD: Heilongjiang University of Chinese Medicine 2002.09 – 2004.08 Postdoctoral: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Work Experience	2004.09 – 2006.11 Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher 2006.11 – 2015.12 Fudan University School of Pharmacy, Department of Biopharmaceutical Sciences - Lecturer 2016.01 – Present Fudan University School of Pharmacy, Department of Biopharmaceutical Sciences - Associate Professor

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1991.09 – 2002.07 Bachelor's, Master's, PhD: Heilongjiang University of Chinese Medicine
2002.09 – 2004.08 Postdoctoral: Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Work Experience

2004.09 – 2006.11 Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
2006.11 – 2015.12 Fudan University School of Pharmacy, Department of Biopharmaceutical Sciences - Lecturer
2016.01 – Present Fudan University School of Pharmacy, Department of Biopharmaceutical Sciences - Associate Professor

Areas of Focus	Discovery of antiviral traditional Chinese medicine activity, efficacy evaluation, and mechanism of action research Host barrier protection and immune regulation mechanisms of anti-infective drugs
Publications	Rhei Radix et Rhizoma in Xuanbai-Chengqi decoction strengthens the intestinal barrier function and promotes lung barrier repair in preventing severe viral pneumonia induced by influenza A virus, Linfeng Guo, Weilian Bao, Shuiyuan Yang, Yang Liu, Jiaren Lyu, Ting Wang, Yan Lu, Hong Li, Haiyan Zhu, Daofeng Chen, 2023 Vunakizumab-IL22, a novel fusion protein, promotes intestinal epithelial repair and protects against gut injury induced by the influenza virus, Chenchen Shi, Chang Su, Lifeng Cen, Lei Han, Jianguo Tang, Zetian Wang, Xunlong Shi, Dianwen Ju, Yiou Cao, Haiyan Zhu, 2023 The protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice, YuanZhen Hao, LiFeng Cen, Ting Wang, Tong Yi, Xun-Long Shi, HuiJuan Duan, Zhi Dai, HaiYan Zhu, JianGuo Tang, 2023 Intestinal microbiota metabolizing Houttuynia cordata polysaccharides in H1N1 induced pneumonia mice contributed to Th17/Treg rebalance in gut-lung axis, Chenchen Shi, Lishuang Zhou, Hong Li, Xunlong Shi, Yunyi Zhang, Yan Lu, Haiyan Zhu, Daofeng Chen, 2022 Integrated network pharmacology and intestinal flora analysis to determine the protective effect of Xuanbai-Chengqi decoction on lung and gut injuries in influenza virus-infected mice, Jinlin Huo, Ting Wang, Bokai Wei, Xunlong Shi, Aidong Yang, Daofeng Chen, Jing Hu, Haiyan Zhu, 2022 Therapeutic potential of 2-Methylquinazolin-4(3H)-one as an antiviral agent against influenza A virus-induced acute lung injury in mice, Rong Tian, Peng Tu, Hai Huang, Haiyan Zhu, Yan Lu, Xunlong Shi, Hong Li, Daofeng Chen, 2022 Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Infection Activation of Aryl Hydrocarbon Receptor, Zetian Wang, Liping Yin, Yue Qi, Jiali Zhang, Haiyan Zhu, Jianguo Tang, 2022 Neutrophil extracellular traps mediate severe lung injury induced by influenza A virus H1N1 in mice coinfected with Staphylococcus aureus, Tong Yi, Wenxin Ding, Yuanzhen Hao, Lifeng Cen, Jiyang Li, Xunlong Shi, Ting Wang, Daofeng Chen, Haiyan Zhu, 2022 Houttuynia Cordata Polysaccharides alleviate the ulcerative colitis by restoring the intestinal homeostasis, Lifeng Cen, Tong Yi, Yuanzhen Hao, Chenchen Shi, Xunlong Shi, Yan Lu, Daofeng Chen, Haiyan Zhu, 2022 A novel bifunctional fusion protein, vunakizumab-IL22, for protection against pulmonary immune injury caused by influenza virus, Lei Han, Chenchen Shi, Xian Zeng, Lifeng Cen, Xiaobin Mei, Jiajun Fan, Dianwen Ju, Haiyan Zhu, 2021 Regulating the Balance of Th17/Treg cells in Gut-Lung Axis Contributed to the Therapeutic Effect of Houttuynia cordata Polysaccharides on H1N1-induced Acute Lung Injury, Chenchen Shi, Haiyan Zhu, Hong Li, Donglin Zeng, Xunlong Shi, Yunyi Zhang, Yan Lu, Lijun Ling, Changyue Wang, Daofeng Chen, 2020 Baicalin inhibits influenza A virus infection via amplification of M1 macrophage polarization, PingGeng, Haiyan Zhu, Wei Zhou, Chang Su, Mingcang Chen, Chenggang Huang, Chengjie Xia, Hai Huang, Yiou Cao, Xunlong Shi, 2020 Houttuynia cordata polysaccharides ameliorate pneumonia severity and intestinal injury in mice with influenza virus infection, Haiyan Zhu, Xiaoxiao Lu, Lijun Ling, Hong Li, Yingye Ou, Xunlong Shi, Yan Lu, Yunyi Zhang, Daofeng Chen, 2018

Areas of Focus

Discovery of antiviral traditional Chinese medicine activity, efficacy evaluation, and mechanism of action research
Host barrier protection and immune regulation mechanisms of anti-infective drugs

Publications

Rhei Radix et Rhizoma in Xuanbai-Chengqi decoction strengthens the intestinal barrier function and promotes lung barrier repair in preventing severe viral pneumonia induced by influenza A virus, Linfeng Guo, Weilian Bao, Shuiyuan Yang, Yang Liu, Jiaren Lyu, Ting Wang, Yan Lu, Hong Li, Haiyan Zhu, Daofeng Chen, 2023
Vunakizumab-IL22, a novel fusion protein, promotes intestinal epithelial repair and protects against gut injury induced by the influenza virus, Chenchen Shi, Chang Su, Lifeng Cen, Lei Han, Jianguo Tang, Zetian Wang, Xunlong Shi, Dianwen Ju, Yiou Cao, Haiyan Zhu, 2023
The protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice, YuanZhen Hao, LiFeng Cen, Ting Wang, Tong Yi, Xun-Long Shi, HuiJuan Duan, Zhi Dai, HaiYan Zhu, JianGuo Tang, 2023
Intestinal microbiota metabolizing Houttuynia cordata polysaccharides in H1N1 induced pneumonia mice contributed to Th17/Treg rebalance in gut-lung axis, Chenchen Shi, Lishuang Zhou, Hong Li, Xunlong Shi, Yunyi Zhang, Yan Lu, Haiyan Zhu, Daofeng Chen, 2022
Integrated network pharmacology and intestinal flora analysis to determine the protective effect of Xuanbai-Chengqi decoction on lung and gut injuries in influenza virus-infected mice, Jinlin Huo, Ting Wang, Bokai Wei, Xunlong Shi, Aidong Yang, Daofeng Chen, Jing Hu, Haiyan Zhu, 2022
Therapeutic potential of 2-Methylquinazolin-4(3H)-one as an antiviral agent against influenza A virus-induced acute lung injury in mice, Rong Tian, Peng Tu, Hai Huang, Haiyan Zhu, Yan Lu, Xunlong Shi, Hong Li, Daofeng Chen, 2022
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Infection Activation of Aryl Hydrocarbon Receptor, Zetian Wang, Liping Yin, Yue Qi, Jiali Zhang, Haiyan Zhu, Jianguo Tang, 2022
Neutrophil extracellular traps mediate severe lung injury induced by influenza A virus H1N1 in mice coinfected with Staphylococcus aureus, Tong Yi, Wenxin Ding, Yuanzhen Hao, Lifeng Cen, Jiyang Li, Xunlong Shi, Ting Wang, Daofeng Chen, Haiyan Zhu, 2022
Houttuynia Cordata Polysaccharides alleviate the ulcerative colitis by restoring the intestinal homeostasis, Lifeng Cen, Tong Yi, Yuanzhen Hao, Chenchen Shi, Xunlong Shi, Yan Lu, Daofeng Chen, Haiyan Zhu, 2022
A novel bifunctional fusion protein, vunakizumab-IL22, for protection against pulmonary immune injury caused by influenza virus, Lei Han, Chenchen Shi, Xian Zeng, Lifeng Cen, Xiaobin Mei, Jiajun Fan, Dianwen Ju, Haiyan Zhu, 2021
Regulating the Balance of Th17/Treg cells in Gut-Lung Axis Contributed to the Therapeutic Effect of Houttuynia cordata Polysaccharides on H1N1-induced Acute Lung Injury, Chenchen Shi, Haiyan Zhu, Hong Li, Donglin Zeng, Xunlong Shi, Yunyi Zhang, Yan Lu, Lijun Ling, Changyue Wang, Daofeng Chen, 2020
Baicalin inhibits influenza A virus infection via amplification of M1 macrophage polarization, PingGeng, Haiyan Zhu, Wei Zhou, Chang Su, Mingcang Chen, Chenggang Huang, Chengjie Xia, Hai Huang, Yiou Cao, Xunlong Shi, 2020
Houttuynia cordata polysaccharides ameliorate pneumonia severity and intestinal injury in mice with influenza virus infection, Haiyan Zhu, Xiaoxiao Lu, Lijun Ling, Hong Li, Yingye Ou, Xunlong Shi, Yan Lu, Yunyi Zhang, Daofeng Chen, 2018

Antiviral Traditional Chinese Medicine Efficacy Evaluation Mechanism Of Action Host Barrier Protection Immune Regulation Anti-Infective Drugs Research Discovery Evaluation

Huang Hai - Fudan University

Guoxun Yang - Fudan University

Demin Zhou - Peking University

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