Areas of Focus
- Stem Cell and Organoid Disease Modeling
- Non-Human Primate Large Animal Models for Visual Diseases
- Biomimetic Perfusion Multi-Organ/Organoid Chip Applications
Work Experience
- 2022-07 to Present - South China Agricultural University - Associate Professor
- 2015-07 to 2016-07 - Lanzhou University First Hospital - Research Intern
Academic Background & Achievements
- 2019-07 to 2022-06 Postdoctoral Research: Guangzhou Overseas Chinese Hospital
- 2016-09 to 2019-07 PhD in Science: Jinan University
- 2012-09 to 2015-07 MSc in Science: Jinan University
- 2008-09 to 2012-07 BEng: Lanzhou Jiaotong University
- Published over 30 SCI papers
- Applied for 4 Chinese invention patents
- Led 5 national and provincial projects
Publications
- Retinal organoids and microfluidic chip-based approaches to explore the retinitis pigmentosa with USH2A mutations, Ting Su, Liying Liang, Lan Zhang, Jianing Wang, Lvyin Chen, Caiying Su, Jixing Cao, Quan Yu, Shuai Deng, Hon Fai Chan, Shibo Tang, Yonglong Guo*, Jiansu Chen*, 2022
- Establishment of iPS cell line (KLRMMEi002-A) by reprogramming peripheral blood mononuclear cells from a patient with USH2A-associated Usher syndrome, Liying Liang, Yunxia Xue, Caiying Su, Jianing Wang, Luyin Chen, Ting Su, Jianyu Ke, Linyao Xie, Zekai Cui, Quan Yu, Hon Fai Chan, Jingxiang Zhong, Yonglong Guo*, Jiansu Chen*, 2022
- Muse cell spheroids have therapeutic effect on corneal scarring wound in mice and tree shrews, Yonglong Guo, Yunxia Xue, Peiyuan Wang, Zekai Cui, Jixing Cao, Shiwei Liu, Quan Yu, Qiaolang Zeng, Deliang Zhu, Mengyuan Xie, Jun Zhang, Zhijie Li, Hongwei Liu, Jingxiang Zhong, Jiansu Chen, 2020
- Modeling retinitis pigmentosa: retinal organoids generated from the iPSCs of a patient with the USH2A mutation show early developmental abnormalities, Yonglong Guo, Peiyuan Wang, Jacey Hongjie Ma, Zekai Cui, Quan Yu, Shiwei Liu, Yunxia Xue, Deliang Zhu, Jixing Cao, Zhijie Li, Shibo Tang, Jiansu Chen, 2019
- Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa, Yonglong Guo, Qiaolang Zeng, Shiwei Liu, Quan Yu, Peiyuan Wang, Hongjie Ma, Shanshan Shi, Xin Yan, Zekai Cui, Mengyuan Xie, Yunxia Xue, Qingbing Zha, Zhijie Li, Jun Zhang, Shibo Tang, Jiansu Chen, 2018