Professor | Yinbo Niu | Asia Growth Partners

Name	Yinbo Niu
Contact Information	ybniuniu@nwpu.edu.cn
Language ability	Chinese, English
Province	Shaanxi

Name

Yinbo Niu

Contact Information

ybniuniu@nwpu.edu.cn

Language ability

Chinese, English

Province

Shaanxi

University/Lab Affiliation and Title	Northwestern Polytechnical University
Faculty	Life Science
Academic Background & Achievements	PhD in Man-Machine and Environmental Engineering from Northwestern Polytechnical University (Supervisor: Professor Qi Bing Mei) Master in Zoology from Northwest University (Supervisor: Professor Zhang Fu Chang) Bachelor in Biological Sciences from Northwest University (Advisor: Professor Gao Yun Fang)
Work Experience	2015.05~Present, Northwestern Polytechnical University, School of Life Sciences, Associate Professor 2018.11~2019.11, Harvard Medical School, Visiting Scholar (Cooperative Supervisor: Roland Baron) 2013.06~2015.04, Northwestern Polytechnical University, School of Life Sciences, Lecturer 2011.07~2013.06, Northwestern Polytechnical University, School of Life Sciences, Postdoctoral Researcher
Awards	2023 Second Prize in the Second 'Course Ideology and Politics Training' at Northwestern Polytechnical University 2023 Second Prize in the Teaching Innovation Competition for Teachers at Northwestern Polytechnical University 2023 First Prize in the Teaching Achievement Award (Undergraduate) at Northwestern Polytechnical University (Rank: 4/8) 2021 Second Prize in the Teaching Innovation Competition for Teachers at Northwestern Polytechnical University 2021 First Prize in the Teaching Innovation Competition for Teachers at the School of Life Sciences, Northwestern Polytechnical University 2020 Outstanding Class Director at Northwestern Polytechnical University 2011 Scholarship Award at Northwestern Polytechnical University 2010 Second Prize in the National Medical Academic Paper Competition, paper included in 'Modern Chinese Medical Series' 2009 '611' Special Award at Northwestern Polytechnical University

University/Lab Affiliation and Title

Northwestern Polytechnical University

Faculty

Life Science

Academic Background & Achievements

PhD in Man-Machine and Environmental Engineering from Northwestern Polytechnical University (Supervisor: Professor Qi Bing Mei)
Master in Zoology from Northwest University (Supervisor: Professor Zhang Fu Chang)
Bachelor in Biological Sciences from Northwest University (Advisor: Professor Gao Yun Fang)

Work Experience

2015.05~Present, Northwestern Polytechnical University, School of Life Sciences, Associate Professor
2018.11~2019.11, Harvard Medical School, Visiting Scholar (Cooperative Supervisor: Roland Baron)
2013.06~2015.04, Northwestern Polytechnical University, School of Life Sciences, Lecturer
2011.07~2013.06, Northwestern Polytechnical University, School of Life Sciences, Postdoctoral Researcher

Awards

2023 Second Prize in the Second 'Course Ideology and Politics Training' at Northwestern Polytechnical University
2023 Second Prize in the Teaching Innovation Competition for Teachers at Northwestern Polytechnical University
2023 First Prize in the Teaching Achievement Award (Undergraduate) at Northwestern Polytechnical University (Rank: 4/8)
2021 Second Prize in the Teaching Innovation Competition for Teachers at Northwestern Polytechnical University
2021 First Prize in the Teaching Innovation Competition for Teachers at the School of Life Sciences, Northwestern Polytechnical University
2020 Outstanding Class Director at Northwestern Polytechnical University
2011 Scholarship Award at Northwestern Polytechnical University
2010 Second Prize in the National Medical Academic Paper Competition, paper included in 'Modern Chinese Medical Series'
2009 '611' Special Award at Northwestern Polytechnical University

Areas of Focus	Mechanisms of bone loss in special environments Natural medicinal protection against bone loss Bone tissue damage and repair
Publications	Asperosaponin VI protects against bone loss due to hindlimb unloading in skeletally growing mice through regulating microbial dysbiosis altering the 5-HT pathway, Niu YB, Zhang YH, Sun Y, Song XZ, Li ZH, Xie M, Li YH, Chen Q, 2023 Short-chain fatty acids regulate bone metabolism: Research progress on mechanisms and effects, Zhang YH, Mei QB, Niu YB*, 2021 Deletion of the matrix-degrading enzymes MMP13 and Cathepsin K in osteocytes regulates osteocytic osteolysis and bone mass, protecting the skeleton in lactating mice, Niu YB, Zhang JM, Orimoto A, Liang S, Hu D, Dann P, Brooks D, Bouxsein ML, Wysolmerski J, Gori F, Baron R, 2020 Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis, Niu YB, Yang YY, Xiao X, Sun Y, Zhou YM, Zhang YH, Dong D, Li CR, Wu XL, Li YH, Mei QB, 2020 Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization, Sun Y, Diao FR, Niu YB(co-first author), Li XQ, Zhou H, Mei QB, Li YH, 2020 A comparative study on the effect of promoting the osteogenic function of osteoblasts using isoflavones from Radix Astragalus, Kong XH, Wang F, Niu YB, Wu XL, Pan YL, 2018 An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer, Li YH, Fan L, Niu YB, Mian W, Zhang F, Xie M, Sun Y, Mei QB, 2017 Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway, Niu YB, Kong XH, Li YH, Pan YL, Li CR, Wu XL, Lu TL, Mei QB, 2015 Du-zhong (Eucommia ulmoides) prevents disuse-induced osteoporosis in hind limb suspension rats, Pan YL, Niu YB, Li CR, Zhai YK, Zhang R, Guo X, Mei QB, 2014 An apple oligogalactan potentiates the growth inhibitory effect of celecoxib on colorectal cancer, Li YH, Niu YB(co-first author), Sun Y, Mei L, Zhang BL, Li Q, Liu L, Zhang R, Chen J, Mei QB, 2014 The beneficial effect of Radix Dipsaci total saponins on bone metabolism in vitro and in vivo and the possible mechanisms of action, Niu YB, Li YH, Kong XH, Zhang R, Sun Y, Li Q, Li C, Liu L, Wang J, Mei QB, 2012 Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways, Kong X, Niu YB, Song XM, Zhao DD, Wang J, Wu XL, Zhang R, Mei QB, 2012 Asperosaponin VI, a saponin component from Dipsacus asper Wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway, Niu YB, Li YH, Huang HT, Kong XH, Zhang R, Liu L, Sun Y, Wang TM, Mei QB, 2011 Modified apple polysaccharides could induce apoptosis in colorectal cancer cells, Li YH, Niu YB(co-first author), Wu HJ, Sun Y, Li Q, Kong XH, Liu L, Mei Q, 2010 PC-407, a celecoxib derivative, inhibited the growth of colorectal tumor in vitro and in vivo, Li YH, Niu YB(co-first author), Wu HJ, Zhang BL, Sun Y, Huang HT, Li Q, Fan L, Liu L, Mei QB, 2009

Areas of Focus

Mechanisms of bone loss in special environments
Natural medicinal protection against bone loss
Bone tissue damage and repair

Publications

Asperosaponin VI protects against bone loss due to hindlimb unloading in skeletally growing mice through regulating microbial dysbiosis altering the 5-HT pathway, Niu YB, Zhang YH, Sun Y, Song XZ, Li ZH, Xie M, Li YH, Chen Q, 2023
Short-chain fatty acids regulate bone metabolism: Research progress on mechanisms and effects, Zhang YH, Mei QB, Niu YB*, 2021
Deletion of the matrix-degrading enzymes MMP13 and Cathepsin K in osteocytes regulates osteocytic osteolysis and bone mass, protecting the skeleton in lactating mice, Niu YB, Zhang JM, Orimoto A, Liang S, Hu D, Dann P, Brooks D, Bouxsein ML, Wysolmerski J, Gori F, Baron R, 2020
Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis, Niu YB, Yang YY, Xiao X, Sun Y, Zhou YM, Zhang YH, Dong D, Li CR, Wu XL, Li YH, Mei QB, 2020
Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization, Sun Y, Diao FR, Niu YB(co-first author), Li XQ, Zhou H, Mei QB, Li YH, 2020
A comparative study on the effect of promoting the osteogenic function of osteoblasts using isoflavones from Radix Astragalus, Kong XH, Wang F, Niu YB, Wu XL, Pan YL, 2018
An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer, Li YH, Fan L, Niu YB, Mian W, Zhang F, Xie M, Sun Y, Mei QB, 2017
Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway, Niu YB, Kong XH, Li YH, Pan YL, Li CR, Wu XL, Lu TL, Mei QB, 2015
Du-zhong (Eucommia ulmoides) prevents disuse-induced osteoporosis in hind limb suspension rats, Pan YL, Niu YB, Li CR, Zhai YK, Zhang R, Guo X, Mei QB, 2014
An apple oligogalactan potentiates the growth inhibitory effect of celecoxib on colorectal cancer, Li YH, Niu YB(co-first author), Sun Y, Mei L, Zhang BL, Li Q, Liu L, Zhang R, Chen J, Mei QB, 2014
The beneficial effect of Radix Dipsaci total saponins on bone metabolism in vitro and in vivo and the possible mechanisms of action, Niu YB, Li YH, Kong XH, Zhang R, Sun Y, Li Q, Li C, Liu L, Wang J, Mei QB, 2012
Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways, Kong X, Niu YB, Song XM, Zhao DD, Wang J, Wu XL, Zhang R, Mei QB, 2012
Asperosaponin VI, a saponin component from Dipsacus asper Wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway, Niu YB, Li YH, Huang HT, Kong XH, Zhang R, Liu L, Sun Y, Wang TM, Mei QB, 2011
Modified apple polysaccharides could induce apoptosis in colorectal cancer cells, Li YH, Niu YB(co-first author), Wu HJ, Sun Y, Li Q, Kong XH, Liu L, Mei Q, 2010
PC-407, a celecoxib derivative, inhibited the growth of colorectal tumor in vitro and in vivo, Li YH, Niu YB(co-first author), Wu HJ, Zhang BL, Sun Y, Huang HT, Li Q, Fan L, Liu L, Mei QB, 2009

Bone Loss Special Environments Mechanisms Natural Medicine Protection Bone Tissue Damage Repair Osteoporosis Pharmacology

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