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Ji-Yong Zhou
Animal Science
Zhejiang University
Zhejiang
Language: Chinese, English
Virology
Immunology
Infectious Diseases
Pathogenesis
Immunoprophylaxis
Epidemiology
Virus Replication
Autophagy
Innate Immunity
Virus-Host Interaction
Areas of Focus
- Molecular Virology and Immunology
- Pathogenesis and Immunoprophylaxis of Infectious Diseases
- Epidemiology
Work Experience
- Current - Zhejiang University - Director of Animal Medical Center
- Current - Zhejiang University - Director of Animal Preventive Medicine Research Institute
- Current - Ministry of Agriculture - Director of Animal Virology Laboratory
Academic Background & Achievements
- National Outstanding Youth Science Fund Winner (2006)
- Changjiang Scholar Distinguished Professor (2009)
- National 'Ten Thousand Talents Program' Science and Technology Innovation Leading Talent (First Batch)
Publications
- TRAF6 autophagic degradation by Avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation, Deng T, Hu B, Wang X, Ding S, Lin L, Yan Y, Peng X, Zheng X, Liao M, Jin Y, Dong W, Gu J, Zhou JY*, 2022
- DeSUMOylation of apoptosis inhibitor-5 by avibirnavirus VP3 supports virus replication, Deng T, Hu B, Wang X, Yan Y, Zhou J, Lin L, Xu Y, Zheng X, Zhou J*, 2021
- Inhibition of antiviral innate Immunity by avibirnavirus VP3 via blocking TBK1-TRAF3 complex formation and IRF3 activation, Deng T, Hu B, Wang X, Lin L, Zhou J, Xu Y, Yan Y, Zheng X, Zhou JY*, 2021
- HFE inhibits Type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation, Liu J, Wu X, Wang H, Wei J, Wu Q, Wang X, Yan Y, Cui J，Min J, Wang F*, Zhou J*, 2021
- PDPK1 regulates autophagosome biogenesis by binding to PIK3C3, Hu B, Zhang Y, Deng T, Gu J, Liu J, Yang H, Yu T, Yan Y, Yang F, Zhang H, Jin Y, Zhou J*, 2021
- Conformational Dynamics of Nonenveloped Circovirus Capsid to the Host Cell Receptor, Li J, Gu J*, Lin C, Zhou J, Wang S, Lei J, Wen F, Sun B, Zhou J*, 2020
- Cytoplasmic Cargo Receptor p62 Inhibits Avibirnavirus Replication by Mediating Autophagic Degradation of Viral Protein VP2, Li Y, Hu B*, Ji G, Zhang Y, Xu C, Lei J, Ding C, Zhou J*, 2020
- Binding of avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway, Zhang Y, Hu B, Li Y, Deng T, Xu Y, Lei J, Zhou J*, 2020
- Novel circovirus species identified in farmed pigs designated as Porcine circovirus 4, Hunan province, China, Zhang H, Hu W, Li J, Liu T, Zhou J*, Opriessnig T, Xiao C*, 2020
- Insights into species-specific regulation of ANP32A on the mammalian-restricted influenza virus polymerase activity, Bi Z, Ye H, Wang X, Fang A, Yu T, Yan L*, Zhou J*, 2019
- Conformational Changes and Nuclear Entry of Porcine Circovirus without Disassembly, Wang H, Zhang K, Lin C, Zhou J, Jin Y, Dong W, Gu J*, Zhou J*, 2019
- A new segmented virus associated with human febrile illness in China, Wang Z, Wang B, Wei F, Han S, Zhang L, Yang Z, Yan Y, Lv X, Li L, Wang S, Song M, Zhang H, Huang S, Chen J, Huang F, Li S, Liu H, Hong J, Jin Y, Wang W*, Zhou J*, Liu Q*, 2019
- SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1, Wu H, Yang H, Ji G, Zheng T, Zhang Y, Deng T, Zheng X, Zhou J*, Hu B*, 2019
- Ubiquitination is Essential for Avibirnavirus Replication by Supporting VP1 Polymerase Activity, Wu H, Shi L, Zhang Y, Peng X, Zheng T, Li Y, Hu B, Zheng X, Zhou J*, 2019
- Caspase-dependent apoptosis induction via viral protein ORF4 of porcine circovirus 2 binding to mitochondrial adenine nucleotide translocase 3, Lin C, Gu J, Wang H, Zhou J, Li J, Wang S, Jin Y, Liu C, Liu J, Yang H, Jiang P, Zhou J*, 2018
- BECN1-dependent casp2 incomplete autophagy induction by binding to rabies virus phosphoprotein, Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, Xu Y, Yan Y, Zan J, Liao M, Erin D, Li J, Su S, Zhou JY*, 2017
- Newly Emergent Highly Pathogenic H5N9 Subtype Avian Influenza A Virus, Yu Y, Wang X, Jin T, Wang H, Si W, Yang H, Wu J, Yan Y, Liu G, Sang X, Wu X, Gao Y, Xia X, Yu X, Pan J, Gao F, Zhou JY*, 2015
- Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway, Hu B, Zhang Y, Jia L, Wu H, Fan C, Sun Y, Ye C, Liao M, Zhou J*, 2015
- Circovirus Transport Proceeds via Direct Interaction of the Cytoplasmic Dynein IC1 Subunit with the Viral Capsid Protein, Cao J, Lin C, Wang H, Wang L, Zhou N, Jin Y, Liao M, Zhou J*, 2015
Awards
- National Technology Invention Award Second Prize
- Science and Technology Progress Award Second Prize
- Natural Science Award Second Prize
- Zhejiang Province Technology Invention Award First Prize
- National New Veterinary Drug Registration Certificate (3)
- National Invention Patent Authorization (14)
