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周继勇
Animal Science
浙江大学
浙江
Language: 中文, 英文
病毒学
免疫学
传染病
发病机制
免疫预防
流行病学
病毒复制
自噬
先天免疫
病毒-宿主相互作用
Areas of Focus
- 分子病毒学与免疫学
- 传染病发病机制与免疫预防技术
- 流行病学
Work Experience
- 现任 - 浙江大学 - 动物医学中心主任
- 现任 - 浙江大学 - 动物预防医学研究所所长
- 现任 - 农业部 - 动物病毒学实验室主任
Academic Background & Achievements
- 国家杰出青年科学基金获得者（2006年）
- 长江学者特聘教授（2009年）
- 国家“万人计划”科技创新领军人才（首批）
Publications
- TRAF6 autophagic degradation by Avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation, Deng T, Hu B, Wang X, Ding S, Lin L, Yan Y, Peng X, Zheng X, Liao M, Jin Y, Dong W, Gu J, Zhou JY*, 2022
- DeSUMOylation of apoptosis inhibitor-5 by avibirnavirus VP3 supports virus replication, Deng T, Hu B, Wang X, Yan Y, Zhou J, Lin L, Xu Y, Zheng X, Zhou J*, 2021
- Inhibition of antiviral innate Immunity by avibirnavirus VP3 via blocking TBK1-TRAF3 complex formation and IRF3 activation, Deng T, Hu B, Wang X, Lin L, Zhou J, Xu Y, Yan Y, Zheng X, Zhou JY*, 2021
- HFE inhibits Type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation, Liu J, Wu X, Wang H, Wei J, Wu Q, Wang X, Yan Y, Cui J，Min J, Wang F*, Zhou J*, 2021
- PDPK1 regulates autophagosome biogenesis by binding to PIK3C3, Hu B, Zhang Y, Deng T, Gu J, Liu J, Yang H, Yu T, Yan Y, Yang F, Zhang H, Jin Y, Zhou J*, 2021
- Conformational Dynamics of Nonenveloped Circovirus Capsid to the Host Cell Receptor, Li J, Gu J*, Lin C, Zhou J, Wang S, Lei J, Wen F, Sun B, Zhou J*, 2020
- Cytoplasmic Cargo Receptor p62 Inhibits Avibirnavirus Replication by Mediating Autophagic Degradation of Viral Protein VP2, Li Y, Hu B*, Ji G, Zhang Y, Xu C, Lei J, Ding C, Zhou J*, 2020
- Binding of avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway, Zhang Y, Hu B, Li Y, Deng T, Xu Y, Lei J, Zhou J*, 2020
- Novel circovirus species identified in farmed pigs designated as Porcine circovirus 4, Hunan province, China, Zhang H, Hu W, Li J, Liu T, Zhou J*, Opriessnig T, Xiao C*, 2020
- Insights into species-specific regulation of ANP32A on the mammalian-restricted influenza virus polymerase activity, Bi Z, Ye H, Wang X, Fang A, Yu T, Yan L*, Zhou J*, 2019
- Conformational Changes and Nuclear Entry of Porcine Circovirus without Disassembly, Wang H, Zhang K, Lin C, Zhou J, Jin Y, Dong W, Gu J*, Zhou J*, 2019
- A new segmented virus associated with human febrile illness in China, Wang Z, Wang B, Wei F, Han S, Zhang L, Yang Z, Yan Y, Lv X, Li L, Wang S, Song M, Zhang H, Huang S, Chen J, Huang F, Li S, Liu H, Hong J, Jin Y, Wang W*, Zhou J*, Liu Q*, 2019
- SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1, Wu H, Yang H, Ji G, Zheng T, Zhang Y, Deng T, Zheng X, Zhou J*, Hu B*, 2019
- Ubiquitination is Essential for Avibirnavirus Replication by Supporting VP1 Polymerase Activity, Wu H, Shi L, Zhang Y, Peng X, Zheng T, Li Y, Hu B, Zheng X, Zhou J*, 2019
- Caspase-dependent apoptosis induction via viral protein ORF4 of porcine circovirus 2 binding to mitochondrial adenine nucleotide translocase 3, Lin C, Gu J, Wang H, Zhou J, Li J, Wang S, Jin Y, Liu C, Liu J, Yang H, Jiang P, Zhou J*, 2018
- BECN1-dependent casp2 incomplete autophagy induction by binding to rabies virus phosphoprotein, Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, Xu Y, Yan Y, Zan J, Liao M,
Awards
- 国家技术发明奖二等奖
- 科技进步奖二等奖
- 自然科学奖二等奖
- 浙江省技术发明奖一等奖
- 国家新兽药注册证书（3个）
- 国家发明专利授权（14件）
