1990 - Master's Degree: Zhejiang Agricultural University
2001 - Ph.D.: Kyoto Institute of Technology, Japan
2006 - Promoted to Professor and Doctoral Supervisor
2006 - Selected as New Century Excellent Talent by the Ministry of Education
Zhejiang Province '151 Talent'
2002.04-2003.04 - University of California, Riverside - Postdoctoral Researcher
2006.12-Present - Zhejiang University - Professor, Doctoral Supervisor
Zhejiang Province Science and Technology Progress Award (Third Prize, 2005)
Zhejiang Province Science and Technology Progress Award (First Prize, 2005)
Shandong Province Science and Technology Progress Award (Second Prize, 2005)
Published over 80 papers, including 45 SCI-indexed papers
8 National Invention Patents
Research
Molecular Biology of Bombyx mori Nucleopolyhedrovirus Genetic Engineering of Baculovirus Interaction between Bombyx mori and Baculovirus
High-level expression of human acidic and basic fibroblast growth factors in the silkworm, Bombyx mori L. using recombinant baculovirus, Xiaofeng Wu, Kaeko Kamei, Hideki Sato, Shin-ichi Sato, Ryo Takano, Masatoshi Ichida, Hajime Mori, and Saburo Hara, 2001
The analysis of heparin-protein interactions using evanescent wave biosensor with regioselectively desulfated heparins as ligands, Kaeko Kamei, Xiaofeng Wu, Xinyan Xu, Kazuhiro Minami, Nguyen Tien Huy, Ryo Takano, Hisao Kato, and Saburo Hara, 2001
Expression of human VEGF165 in silkworm (Bombyx mori L.) by using a recombinant baculovirus and its bioactivity assay, Wu Xiaofeng*, Zhaozheng Yin, Cuiping Cao, Ling Huang, Xingmeng Lu, Jianxin Liu, Weizheng Cui, 2004
An innovative technique for inoculating recombinant baculovirus into the silkworm Bombyx mori using lipofectin, Wu Xiaofeng*, Cao Cuiping, V. Shyam Kumar and Cui Weizheng, 2004
Construction of a host range-expanded hybrid baculovirus of BmNPV and AcNPV, and knockout of Cysteinase gene for more efficient expression, Wu Xiaofeng*, Cao Cuiping, Xu Yaxiang, Lu Xingmen, 2004
Expression of porcine lactoferrin by using recombinant baculovirus in silkworm, Bombyx mori L., and its purification and characterization, Yizhen Wang, Xiaofeng Wu*, Guangfu Liu, Cuiping Cao, Haiqing Huang, Zirong Xu, Jianxin Liu, 2005
Increased resistance to white spot syndrome virus in Procambarus clarkii by injection of envelope protein VP28 expressed using recombinant baculovirus, Huahua Du, Xiaofeng Wu*, Weifen Li, Wei Dai, 2006
Development of a rapid and efficient BmNPV baculovirus expression system for application in mulberry silkworm, Bombyx mori, Cuiping Cao, Xingmeng Lu, Na Zhao, Huipeng Yao, Xiaofeng Wu*, and Yeping Tan, 2006
Enhanced effect of fluorescent whitening agent on peroral infection for recombinant baculovirus in the host Bombyx mori, Bing Wang, Xiaofeng Wu*, Na Zhao, 2007
Efficient production of canine interferon-alpha in silkworm Bombyx mori by use of a BmNPV/Bac-to-Bac expression system, Zhao Na,Yao Huipeng,Lan Lipan,Cao Cuiping,M. L. Umashankar,Lu Xingmeng,Wu Xiaofeng*,Wang Bing,Cui Weizheng, J. L. Cenis, 2008
Gene analysis of an antiviral protein SP-2 from Chinese wild silkworm, Bombyx mandarina Moore and its bioactivity assay, Yao H, He F, Guo A, Cao C, Lu X, Wu X, 2008
Identification of the proteome of the midgut of silkworm, Bombyx mori L. by multidimensional liquid chromatography LTQ-Orbitrap mass spectrometry, Yao HP, Xiang XW, Chen L, Guo AQ, He FQ, Lan LP, Lu XM, Wu XF, 2009
Proteomics identification and annotation of proteins of cell line of Bombyx mori, BmN cell, Hui-peng Yao, Lin Chen, Xingwei Xiang, Ai-qin Guo, Xing-meng Lu, Xiao-feng Wu, 2010
Expression of Trichoderma reesei endo-beta-glucanase II in silkworm, Bombyx mori L. by using BmNPV/Bac-to-Bac expression system and its bioactivity assay, Zhou L, Wu X, Lan L, Liu J, 2010
Construction of a BmNPV polyhedrin-plus Bac-to-Bac baculovirus expression system for application in silkworm, Bombyx mori, Xingwei Xiang, Rui Yang, Shaofang Yu, Cuiping Cao, Aiqin Guo, Lin Chen, Xiaofeng Wu, Weizheng Cui, Cenis J L, 2010
Purification and Kinetic Properties of Human Recombinant Dihydrofolate Reductase Produced in Chrysalides of Bombyx mori, Soledad Chazarra, Salvador Aznar-Cervantes, Luis Sánchez-del-Campo, Juan Cabezas Herrera, Wu Xiaofeng, José Luis Cenis, José Neptuno Rodríguez-López, 2010
Accumulation of 1-deoxynojirimycin in silkworm, Bombyx mori L., Hao YIN, Xin-qin SHI, Bo SUN, Jing-jing YE, Zu-an DUAN1, Xiao-ling ZHOU, Wei-zheng CUI, Xiao-feng WU, 2010
The Bombyx mori nucleopolyhedrovirus (BmNPV) ODV-E56 envelope protein is also a per os infectivity factor, Xingwei Xiang, Lin Chen, Aiqin Guo, Shaofang Yu, Rui Yang, Xiaofeng Wu, 2011
Autographa californica multiple nucleopolyhedrovirus odv-e66 is an essential gene required for oral infectivity, Xingwei Xiang, Lin Chen, Xiaolong Hu, Shaofang Yu, Rui Yang, Xiaofeng Wu, 2011
Immobilization of foreign protein into polyhedra of Bombyx mori nucleopolyhedrovirus (BmNPV), Xingwei Xiang, Lin Chen, Shaofang Yu, Rui Yang, Cuiping Cao, Xiaofeng Wu, 2012
Proteomic analysis of peritrophic membrane (PM) from the midgut of fifth-instar larvae, Bombyx mori, Xiaolong Hu, Lin Chen, Xingwei Xiang, Rui Yang, Shaofang Yu, Xiaofeng Wu, 2012
Autographa californica multiple nucleopolyhedrovirus odv-e25 (Ac94) is required for budded virus infectivity and occlusion-derived virus formation, Lin Chen, Xiaolong Hu, Xingwei Xiang, Rui Yang, Shaofang Yu, Xiaofeng Wu, 2012
Molecular characterization of a peritrophic membrane protein from the silkworm, Hu X, Chen L, Yang R, Xiang X, Wu X, 2013
The formation of occlusion-derived virus was affected by the expression level of ODV-E25, Lin Chen, Rui Yang, Xiao-Long Hu, Xing-Wei Xiang and Xiao-Feng Wu, 2013
Expression analysis of chlorophyllid α binding protein,a secretory, red fluorescence protein in the midgut of silkworm, Bombyx mori, Lin Chen, Rui Yang, Xiao-Long Hu, Xing-Wei Xiang and Xiao-Feng Wu, 2013
Bombyx mori nucleopolyhedrovirus BmP95 plays an essential role in BV production and nucleocapsid assembly, Xiang X, Shen Y, Yang R, Chen L, Hu X, Wu X, 2013
Immobilization of Foreign Protein in BmNPV Polyhedra by fusion expression with partial polyhedrin fragments, Lin Chen, Xingwei Xiang, Rui Yang, Xiaolong Hu, Xiaofeng Wu*, 2013
Molecular cloning and functional characterization of the dual oxidase (BmDuox) gene from the silkworm, Xiaolong Hu, Rui Yang, Xiaofeng Wu, 2013
Shotgun proteomic analysis of Bombyx mori brain: emphasis on regulation of behavior and development of the nervous system, Guobao Wang. Qin Zheng, Yunwang Shen, Xiaofeng Wu, 2014
Transcriptome analysis of the brain of the silkworm Bombyx mori infected with Bombyx mori nucleopolyhedrovirus: A new insight into the molecular mechanism of enhanced locomotor activity induced by viral infection, Guobao Wang; Jianjia Zhang; Yunwang Shen; Qin Zheng; Min Feng; Xingwei Xiang,Xiaofeng Wu, 2015
Development of an enzyme-linked-immunosorbent-assay technique for accurate identification of poorly preserved silks unearthed in ancient tombs, Zheng Q, Wu X, Zheng H, Zhou Y, 2015
Bombyx mori nucleopolyhedrovirus (BmNPV) Bm64 is required for BV production and per os infection, Chen L, Shen Y, Yang R, Wu X, 2015
Bm59 is an early gene, but is unessential for the propagation and assembly of Bombyx mori nucleopolyhedrovirus, Xiaolong Hu, Yunwang Shen, Qin zheng, Guobao Wang,
Keywords
Bombyx MoriNucleopolyhedrovirusMolecular BiologyGenetic EngineeringBaculovirusVirus-Host InteractionRecombinant ProteinBioreactorGene ExpressionVaccine Development