Professor | Jian You | Asia Growth Partners

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Name	Jian You
Contact Information	youjiandoc@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Jian You

Contact Information

youjiandoc@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Pharmaceutical Sciences
Work Experience	2013-2021 - Zhejiang University - Lecturer for Industrial Pharmaceutics and Industrial Pharmaceutics Experiment 2022-Present - Zhejiang University - Lecturer for Pharmaceutics and Pharmaceutics Experiment
Awards	National Ten Thousand Talents Program (2020) Ministry of Science and Technology Young and Middle-aged Science and Technology Innovation Leading Talent (2019) First Prize of Zhejiang Science and Technology Progress Award (2017) First Prize of Zhejiang Medical and Health Science and Technology Award (2015) First Prize of Zhejiang Science and Technology Progress Award (2014) Third Prize of Zhejiang Science and Technology Progress Award (2007) Second Prize of the Ministry of Education Natural Science Award (2009) Chinese Pharmaceutical Association Young Pharmaceutics Award (2012)

University/Lab Affiliation and Title

Zhejiang University

Faculty

Pharmaceutical Sciences

Work Experience

2013-2021 - Zhejiang University - Lecturer for Industrial Pharmaceutics and Industrial Pharmaceutics Experiment
2022-Present - Zhejiang University - Lecturer for Pharmaceutics and Pharmaceutics Experiment

Awards

National Ten Thousand Talents Program (2020)
Ministry of Science and Technology Young and Middle-aged Science and Technology Innovation Leading Talent (2019)
First Prize of Zhejiang Science and Technology Progress Award (2017)
First Prize of Zhejiang Medical and Health Science and Technology Award (2015)
First Prize of Zhejiang Science and Technology Progress Award (2014)
Third Prize of Zhejiang Science and Technology Progress Award (2007)
Second Prize of the Ministry of Education Natural Science Award (2009)
Chinese Pharmaceutical Association Young Pharmaceutics Award (2012)

Areas of Focus	Pharmaceutical Preparation Engineering Drug Delivery Systems Gene Drugs Immunotherapy Nanomedicine Controlled Release Formulations Long-acting Formulations Vaccine Delivery ER-targeted Drug Delivery Cancer Immunotherapy Cancer Photothermal Therapy
Publications	Chronological management of adjuvant effect for optimized mRNA vaccine inspired by natural virus infection, Zeliang Lou, Yingying Shi, Xuemeng Guo, Zhaolei Jin, Jiaxin Huang, Yilong Hu, Xu Liu, Jiang Zhu, Rong Kuang, and Jian You, 2024 Spleen-targeted delivery systems and strategies for spleen-related diseases, Ziyao Huang, Kedong Sun, Zhenyu Luo, Junlei Zhang, Huanli Zhou, Hang Yin, Zhile Liang, Jian You, 2024 A long-acting lyotropic liquid crystalline implant promotes the drainage of macromolecules by brain-related lymphatic system in treating aged Alzheimer's disease, Shan, Xinyu; Lu, Yichao; Luo, Zhenyu; Zhao, Xiaoqi; Pang, Mei; Yin, Hang; Guo, Xuemeng; Zhou, Huanli; Zhang, Junlei ; Huang, Jiaxin; Shi, Yingying ; Lou, Jinfang; Luo, Lihua; You, Jian, 2024 Mechanisms and measures to modulate T cell trafficking for amplified and tolerogenic immunity, Yichao Lu, Xu Liu, Jian You, 2024 Recent progress in nanoplatform-enhanced photodynamic therapy for the induction of immunogenic cell death, Xu Liu, Yichao Lu, Xiang Li, Lihua Luo, Jian You, 2024 A Nanoemulsion Targeting Adipose Hypertrophy and Hyperplasia Shows Anti-Obesity Efficiency in Female Mice, Yichao Lu, Zhenyu Luo, Huanli Zhou, Yingying Shi, Ying Zhu, Xuemeng Guo, Jiaxin Huang, Junlei Zhang, Xu Liu, Sijie Wang, Xinyu Shan, Hang Yin, Yongzhong Du, Qingpo Li, Jian You, Lihua Luo, 2024 Precisely Regulating M2 Subtype Macrophages for Renal Fibrosis Resolution, Luo, Lihua; Wang, Sijie; Hu, Yilong; Wang, Litong; Jiang, Xindong; Zhang, Junlei; Liu, Xu; Guo, Xuemeng; Luo, Zhenyu; Zhu, Chunqi; Xie, Miaomiao; Li, Yeqing; You, Jian; Yang, Fuchun, 2023 Enhancing Tumor Immunotherapy via Photodynamic Therapy with a Cascade Reaction of Reactive Oxygen Species and Sustaining Nutrient Supply, Xu Liu, Junlei Zhang, Xuemeng Guo, Jiaxin Huang, Zeliang Lou, Xiaoqi Zhao, Qing Lin, Xiang Li, Jian You, and Lihua Luo, 2023 Liposome Vaccine for Active Regulation of Cellular and Humoral Immunity, Lihua Luo, Zhenyu Luo, Litong Wang, Yilong Hu, Junlei Zhang, Hang Yin, Jian You, 2023 Solvent Exchange-Motivated and Tunable in Situ Forming Implants Sustaining Triamcinolone Acetonide Release for Arthritis Treatment, Qin Lin, Xinyu Shan, Xiang Li, Zhenyu Luo, Xin Yu, Huihui Liu, Sijie Wang, Xiaoqi Zhao, Ying Zhu, Huanli Zhou, Lihua Luo, Jian You, 2023 Cell communication-mediated selective drug delivery for epitope-specific deletion of alloreactive T cells in organ transplant, Yingying Shi, Zeliang Lou, Yu Liu, Jiaxin Huang, Yi Wang, Jian You, 2023 Antioxidant nanoemulsion loaded with latanoprost enables highly effective glaucoma treatment, Xuemeng Guo, Junlei Zhang, Xu Liu, Yichao Lu, Yingying Shi, Xiang Li, Sije Wang, Jiaxin Huang, Huihui Liu, Huanli Zhou, Qingpo Li, Lihua Luo, Jian You, 2023 Reductive lipid nanoparticles loaded with vinorelbine inhibit chemotherapy-induced invasion of cancer cells by modulating ENPP2, Xiaoqi Zhao, Xuemeng Guo, Mei Pang, Weigen Qiu, Zhenyu Luo, Qing Lin, Yichao Lu, Hang Yin, Sijie Wang, Huihui Liu, Junlei Zhang, Lihua Luo, Jian You, 2023 The role of protein corona on nanodrugs for organ-targeting and its prospects of application, Sijie Wang, Junlei Zhang, Huanli Zhou, Yi Chao Lu, Xizhi Jin, LihuaLuo, JianYou, 2023 The Effect of Blood Velocity in Solid Tumor on Intratumorally Accumulation and Penetration of Nanocarriers and Drugs, Sijie Wang, Junlei Zhang, Huihui Liu, Xuemeng Guo, Yichao Lu, Guannan Guan, Zhenyu Luo, Mengshi Jiang, Qing Lin, Huanli Zhou, Xiaoqi Zhao, Lihua Luo, Jian You, 2023 The application of nanoparticle-based imaging and phototherapy for female reproductive organs diseases, Lihua Luo, Huanli Zhou, Sijie Wang, Mei Pang, Junlei Zhang, Yilong Hu, Jian You, 2023 Neutrophil Hitchhiking for Drug Delivery to the Bone Marrow, Zhenyu Luo, Yichao Lu, Yingying Shi, Mengshi Jiang, Xinyu Shan, Xiang Li, Junlei Zhang, Bing Qin, Xu Liu, Xuemeng Guo, Jiaxin Huang, Yu Liu, Sijie Wang, Qingpo Li, Lihua Luo, Jian You, 2023 A clinically-achievable injectable and sprayable in-situ lyotropic liquid crystalline platform in treating hormone-sensitive and castration-resistant prostate cancer, Shan, Xinyu; Li, Xiang ; Luo, Zhenyu; Lin, Qing; Lu, Yichao; Jiang, Mengshi; Zhang, Junlei ; Huang, Jiaxin; Xie, Lin ; Guo, Xuemeng; Liu, Xu; Shi, Yingying ; Liu, Yu; Yin, Hang; Yang, Fuchun; Luo, Lihua; You, Jian, 2023 Recruiting T cells and sensitizing tumors to NKG2D immune surveillance for robust antitumor immune response, Xiang Li, Xuemeng Guo, Jiaxin Huang, Qing Lin, Bing Qin, Mengshi Jiang, Xinyu Shan, Zhenyu Luo, Junlei Zhang, Yingying Shi, Yichao Lu, Xu Liu, Yongzhong Du, Fuchun Yang, Lihua Luo, Jian You, 2023 Preventing Acute Lung Injury from Progressing to Pulmonary Fibrosis by Maintaining ERS Homeostasis Through a Multistage Targeting Nanomicelle, Lihua Luo, Zhenyu Luo, Junlei Zhang, Xu Liu, Jiaxin Huang, Sijie Wang, Hang Yin, Xuemeng Guo, Yilong Hu, Yichao Lu, Xinyu Shan, Huihui Liu, Yingying Shi, Yongzhong Du, Fuchun Yang, Jian You, 2022 Non-lysosomal Route of mRNA delivery and Combining with Epigenetic Regulation Optimized antitumor Immunoprophylactic Efficacy, Yu Liu, Xu Liu, Jiaxin Huang, Yingying Shi, Zhenyu Luo, Junlei Zhang, Xuemeng Guo, Mengshi Jiang, Xiang Li, Hang Yin, Bing Qin, Guannan Guan, Lihua Luo, Yun Zhou, Jian You, 2022 Structural and biochemical characteristics of mRNA nanoparticles determine anti-SARS-CoV-2 humoral and cellular immune responses, Yingying Shi, Jiaxin Huang, Yu Liu, Jing Liu, Xuemeng Guo, Jianhua Li, Liming Gong, Xin Zhou, Guofeng Cheng, Yunqing Qiu, Jian You, Yan Lou, 2022 Brucea javanica oil emulsion significantly improved the effect of anti-programmed cell death protein-1 immunotherapy, Jun Meng, Zhixin Yu, Hongying Chen, Xin Yu, Mengshi Jiang, Xin-An Zeng, Jian You, 2022 Arginine supplementation targeting tumor-killing immune cells reconstructs tumor microenvironment and enhances antitumor immune response, Zhang, Junlei ; Wang, Sijie; Guo, Xuemeng; Lu, Yichao; Liu, Xu; Jiang, Mengshi; Li, Xiang ; Qin, Bing; Luo, Zhenyu; Liu, Huihui; Li, Qingpo; Du, Yong-Zhong; Luo, Lihua; You, Jian, 2022 Endoplasmic reticulum-targeted inhibition of CYP2E1 with Vitamin E nanoemulsions alleviates hepatocyte oxidative stress and reverses alcoholic liver disease, Yingying Shi, Yu Liu, Sijie Wang, Jiaxin Huang, Zhenyu Luo, Mengshi Jiang, Yichao Lu, Qing Lin, Huihui Liu, Ningtao Cheng, Jian You, 2022 Antigen transfer and its effect on vaccine-induced immune amplification and tolerance, Yingying Shi, Yichao Lu, Jian You, 2022 New Advances in Pharmaceutical Strategies for Sensitizing Anti-PD-1 Immunotherapy and Clinical Research, Mengshi Jiang, Bing Qin, Xiang Li, Yu Liu, Guannan Guan, Jian You, 2022 A Therapeutic DC Vaccine with Maintained Immunological Activity Exhibits Robust Anti-Tumor Efficacy, Yichao

Areas of Focus

Pharmaceutical Preparation Engineering
Drug Delivery Systems
Gene Drugs
Immunotherapy
Nanomedicine
Controlled Release Formulations
Long-acting Formulations
Vaccine Delivery
ER-targeted Drug Delivery
Cancer Immunotherapy
Cancer Photothermal Therapy

Publications

Chronological management of adjuvant effect for optimized mRNA vaccine inspired by natural virus infection, Zeliang Lou, Yingying Shi, Xuemeng Guo, Zhaolei Jin, Jiaxin Huang, Yilong Hu, Xu Liu, Jiang Zhu, Rong Kuang, and Jian You, 2024
Spleen-targeted delivery systems and strategies for spleen-related diseases, Ziyao Huang, Kedong Sun, Zhenyu Luo, Junlei Zhang, Huanli Zhou, Hang Yin, Zhile Liang, Jian You, 2024
A long-acting lyotropic liquid crystalline implant promotes the drainage of macromolecules by brain-related lymphatic system in treating aged Alzheimer's disease, Shan, Xinyu; Lu, Yichao; Luo, Zhenyu; Zhao, Xiaoqi; Pang, Mei; Yin, Hang; Guo, Xuemeng; Zhou, Huanli; Zhang, Junlei ; Huang, Jiaxin; Shi, Yingying ; Lou, Jinfang; Luo, Lihua; You, Jian, 2024
Mechanisms and measures to modulate T cell trafficking for amplified and tolerogenic immunity, Yichao Lu, Xu Liu, Jian You, 2024
Recent progress in nanoplatform-enhanced photodynamic therapy for the induction of immunogenic cell death, Xu Liu, Yichao Lu, Xiang Li, Lihua Luo, Jian You, 2024
A Nanoemulsion Targeting Adipose Hypertrophy and Hyperplasia Shows Anti-Obesity Efficiency in Female Mice, Yichao Lu, Zhenyu Luo, Huanli Zhou, Yingying Shi, Ying Zhu, Xuemeng Guo, Jiaxin Huang, Junlei Zhang, Xu Liu, Sijie Wang, Xinyu Shan, Hang Yin, Yongzhong Du, Qingpo Li, Jian You, Lihua Luo, 2024
Precisely Regulating M2 Subtype Macrophages for Renal Fibrosis Resolution, Luo, Lihua; Wang, Sijie; Hu, Yilong; Wang, Litong; Jiang, Xindong; Zhang, Junlei; Liu, Xu; Guo, Xuemeng; Luo, Zhenyu; Zhu, Chunqi; Xie, Miaomiao; Li, Yeqing; You, Jian; Yang, Fuchun, 2023
Enhancing Tumor Immunotherapy via Photodynamic Therapy with a Cascade Reaction of Reactive Oxygen Species and Sustaining Nutrient Supply, Xu Liu, Junlei Zhang, Xuemeng Guo, Jiaxin Huang, Zeliang Lou, Xiaoqi Zhao, Qing Lin, Xiang Li, Jian You, and Lihua Luo, 2023
Liposome Vaccine for Active Regulation of Cellular and Humoral Immunity, Lihua Luo, Zhenyu Luo, Litong Wang, Yilong Hu, Junlei Zhang, Hang Yin, Jian You, 2023
Solvent Exchange-Motivated and Tunable in Situ Forming Implants Sustaining Triamcinolone Acetonide Release for Arthritis Treatment, Qin Lin, Xinyu Shan, Xiang Li, Zhenyu Luo, Xin Yu, Huihui Liu, Sijie Wang, Xiaoqi Zhao, Ying Zhu, Huanli Zhou, Lihua Luo, Jian You, 2023
Cell communication-mediated selective drug delivery for epitope-specific deletion of alloreactive T cells in organ transplant, Yingying Shi, Zeliang Lou, Yu Liu, Jiaxin Huang, Yi Wang, Jian You, 2023
Antioxidant nanoemulsion loaded with latanoprost enables highly effective glaucoma treatment, Xuemeng Guo, Junlei Zhang, Xu Liu, Yichao Lu, Yingying Shi, Xiang Li, Sije Wang, Jiaxin Huang, Huihui Liu, Huanli Zhou, Qingpo Li, Lihua Luo, Jian You, 2023
Reductive lipid nanoparticles loaded with vinorelbine inhibit chemotherapy-induced invasion of cancer cells by modulating ENPP2, Xiaoqi Zhao, Xuemeng Guo, Mei Pang, Weigen Qiu, Zhenyu Luo, Qing Lin, Yichao Lu, Hang Yin, Sijie Wang, Huihui Liu, Junlei Zhang, Lihua Luo, Jian You, 2023
The role of protein corona on nanodrugs for organ-targeting and its prospects of application, Sijie Wang, Junlei Zhang, Huanli Zhou, Yi Chao Lu, Xizhi Jin, LihuaLuo, JianYou, 2023
The Effect of Blood Velocity in Solid Tumor on Intratumorally Accumulation and Penetration of Nanocarriers and Drugs, Sijie Wang, Junlei Zhang, Huihui Liu, Xuemeng Guo, Yichao Lu, Guannan Guan, Zhenyu Luo, Mengshi Jiang, Qing Lin, Huanli Zhou, Xiaoqi Zhao, Lihua Luo, Jian You, 2023
The application of nanoparticle-based imaging and phototherapy for female reproductive organs diseases, Lihua Luo, Huanli Zhou, Sijie Wang, Mei Pang, Junlei Zhang, Yilong Hu, Jian You, 2023
Neutrophil Hitchhiking for Drug Delivery to the Bone Marrow, Zhenyu Luo, Yichao Lu, Yingying Shi, Mengshi Jiang, Xinyu Shan, Xiang Li, Junlei Zhang, Bing Qin, Xu Liu, Xuemeng Guo, Jiaxin Huang, Yu Liu, Sijie Wang, Qingpo Li, Lihua Luo, Jian You, 2023
A clinically-achievable injectable and sprayable in-situ lyotropic liquid crystalline platform in treating hormone-sensitive and castration-resistant prostate cancer, Shan, Xinyu; Li, Xiang ; Luo, Zhenyu; Lin, Qing; Lu, Yichao; Jiang, Mengshi; Zhang, Junlei ; Huang, Jiaxin; Xie, Lin ; Guo, Xuemeng; Liu, Xu; Shi, Yingying ; Liu, Yu; Yin, Hang; Yang, Fuchun; Luo, Lihua; You, Jian, 2023
Recruiting T cells and sensitizing tumors to NKG2D immune surveillance for robust antitumor immune response, Xiang Li, Xuemeng Guo, Jiaxin Huang, Qing Lin, Bing Qin, Mengshi Jiang, Xinyu Shan, Zhenyu Luo, Junlei Zhang, Yingying Shi, Yichao Lu, Xu Liu, Yongzhong Du, Fuchun Yang, Lihua Luo, Jian You, 2023
Preventing Acute Lung Injury from Progressing to Pulmonary Fibrosis by Maintaining ERS Homeostasis Through a Multistage Targeting Nanomicelle, Lihua Luo, Zhenyu Luo, Junlei Zhang, Xu Liu, Jiaxin Huang, Sijie Wang, Hang Yin, Xuemeng Guo, Yilong Hu, Yichao Lu, Xinyu Shan, Huihui Liu, Yingying Shi, Yongzhong Du, Fuchun Yang, Jian You, 2022
Non-lysosomal Route of mRNA delivery and Combining with Epigenetic Regulation Optimized antitumor Immunoprophylactic Efficacy, Yu Liu, Xu Liu, Jiaxin Huang, Yingying Shi, Zhenyu Luo, Junlei Zhang, Xuemeng Guo, Mengshi Jiang, Xiang Li, Hang Yin, Bing Qin, Guannan Guan, Lihua Luo, Yun Zhou, Jian You, 2022
Structural and biochemical characteristics of mRNA nanoparticles determine anti-SARS-CoV-2 humoral and cellular immune responses, Yingying Shi, Jiaxin Huang, Yu Liu, Jing Liu, Xuemeng Guo, Jianhua Li, Liming Gong, Xin Zhou, Guofeng Cheng, Yunqing Qiu, Jian You, Yan Lou, 2022
Brucea javanica oil emulsion significantly improved the effect of anti-programmed cell death protein-1 immunotherapy, Jun Meng, Zhixin Yu, Hongying Chen, Xin Yu, Mengshi Jiang, Xin-An Zeng, Jian You, 2022
Arginine supplementation targeting tumor-killing immune cells reconstructs tumor microenvironment and enhances antitumor immune response, Zhang, Junlei ; Wang, Sijie; Guo, Xuemeng; Lu, Yichao; Liu, Xu; Jiang, Mengshi; Li, Xiang ; Qin, Bing; Luo, Zhenyu; Liu, Huihui; Li, Qingpo; Du, Yong-Zhong; Luo, Lihua; You, Jian, 2022
Endoplasmic reticulum-targeted inhibition of CYP2E1 with Vitamin E nanoemulsions alleviates hepatocyte oxidative stress and reverses alcoholic liver disease, Yingying Shi, Yu Liu, Sijie Wang, Jiaxin Huang, Zhenyu Luo, Mengshi Jiang, Yichao Lu, Qing Lin, Huihui Liu, Ningtao Cheng, Jian You, 2022
Antigen transfer and its effect on vaccine-induced immune amplification and tolerance, Yingying Shi, Yichao Lu, Jian You, 2022
New Advances in Pharmaceutical Strategies for Sensitizing Anti-PD-1 Immunotherapy and Clinical Research, Mengshi Jiang, Bing Qin, Xiang Li, Yu Liu, Guannan Guan, Jian You, 2022
A Therapeutic DC Vaccine with Maintained Immunological Activity Exhibits Robust Anti-Tumor Efficacy, Yichao

Pharmaceutical Preparation Drug Delivery Gene Therapy Immunotherapy Nanomedicine Controlled Release Long-Acting Vaccine Er-Targeted Cancer Therapy

Zhiwen Zhang - Fudan University

Yongzhong Du - Zhejiang University

Yiguang Wang - Peking University

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