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Zhiwen Zhang
Pharmaceutical Sciences
Fudan University
Shanghai
Language: Chinese, English
Drug Delivery
Intratumoral Barriers
Nanomedicine
Cancer Therapy
Immunotherapy
Tumor Microenvironment
Nanoparticles
Pharmacokinetics
Biomimetics
Theranostics
Areas of Focus
- Research on new drug delivery systems to overcome intratumoral delivery barriers
Work Experience
- 2022.03-present - Fudan University - Researcher
- 2015.11-2022.02 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
- 2010.11-2015.10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
- 2008.07-2010.10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2005.09-2008.06 PhD: Fudan University, Pharmaceutics
- 2002.09-2005.06 Master's: Shenyang Pharmaceutical University, Pharmaceutics
- 1998.08-2002.06 Bachelor's: Shandong University, Pharmacy
Publications
- Bioinspired lipoproteins of furoxans-oxaliplatin remodels physical barriers in tumor to potentiate T-cell infiltration, Yuqi Wang, Honglei Xie, Yao Wu, Shuzhou Xu, Yongping Li, Jie Li, Xiaoxuan Xu, Siling Wang, Yaping Li, Zhiwen Zhang, 2022
- Oxygen-Delivering Polyfluorocarbon Nanovehicles Improve Tumor Oxygenation and Potentiate Photodynamic-Mediated Antitumor Immunity, Zhiwan Wang, Xiang Gong, Jie Li, Hong Wang, Xiaoxuan Xu, Yaping Li, Xianyi Sha, Zhiwen Zhang, 2021
- Tumor-permeated bioinspired theranostic nanovehicle remodels tumor immunosuppression for cancer therapy, Hong Wang, Jie Li, Zhiwan Wang, Yuqi Wang, Xiaoxuan Xu, Xiang Gong, Jiaoying Wang, Zhiwen Zhang, Yaping Li, 2021
- Tumor-activated size-enlargeable bioinspired lipoproteins access cancer cells in tumor to elicit anti-tumor immune responses, Jie Li, Hong Wang, Yuqi Wang, Xiang Gong, Xiaoxuan Xu, Xianyi Sha, Ao Zhang, Zhiwen Zhang, Yaping Li, 2020
- Orally delivered legumain-activated nanovehicles improve tumor accumulation and penetration for combinational photothermal-chemotherapy, Jing Wang, Yuqi Wang, Haiqiang Cao, Hong Wang, Jie Li, Youxin Li, Yaping Li, Zhiwen Zhang, 2020
- Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy, Junjing Yin, Haiqiang Cao, Hong Wang, Kaoxiang Sun, Yaping Li, Zhiwen Zhang, 2020
- Bioinspired lipoproteins-mediated photothermia remodels tumor stroma to improve cancer cell accessibility of second nanoparticles, Tao Tan, Yuqi Wang, Haiyan Hu, Hong Wang, Jie Li, Zhiwan Wang, Jing Wang, Siling Wang, Zhiwen Zhang, Yaping Li, 2019
- Rational Design of Tumor Microenvironment-Activated Micelles for Programmed Targeting of Breast Cancer Metastasis, Bin He, Tao Tan, Hong Wang, Haiyan Hu, Zhiwan Wang, Jing Wang, Jie Li, Kaoxiang Sun, Zhiwen Zhang, Yaping Li, 2018
- Bioengineered macrophages can responsively transform into nanovesicles to target lung metastasis, Haiqiang Cao, Hong Wang, Xinyu He, Tao Tan, Haiyan Hu, Zhiwan Wang, Jing Wang, Jie Li, Zhiwen Zhang, Yaping Li, 2018
- Albumin Biomimetic Nanocorona Improves Tumor Targeting and Penetration for Synergistic Therapy of Metastatic Breast Cancer, Haiqiang Cao, Lili Zou, Bin He, Lijuan Zeng, Yongzhuo Huang, Haijun Yu, Pengcheng Zhang, Qi Yin, Zhiwen Zhang, Yaping Li, 2017
Awards
- Wang Kuancheng Talent Award (2015): Chinese Academy of Sciences
- Outstanding Member (2016): Youth Innovation Promotion Association, Chinese Academy of Sciences
- National Talent Program Young Top Talent (2020)
- First Prize of Science and Technology Award (2015.3; 2020.2): Chinese Pharmaceutical Association
- Second Prize of National Natural Science Award (2020.4)
