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Yi Wang
zjuwangyi@zju.edu.cn
Chinese, English
Zhejiang

Academic Information

Zhejiang University
Pharmaceutical Sciences
  • Bachelor's Degree: Zhejiang University, Pharmaceutical Engineering
  • Doctoral Degree: Zhejiang University, Pharmaceutical Analysis
  • National Excellent Doctoral Dissertation Nomination Award
  • Zhejiang Province Excellent Doctoral Dissertation
  • Professor, Zhejiang University, College of Pharmaceutical Sciences
  • Deputy Dean, College of Pharmaceutical Sciences, Zhejiang University
  • Deputy Director, Department of Chinese Medicine Science and Engineering, Zhejiang University
  • Visiting Researcher, FDA National Center for Toxicological Research
  • Visiting Researcher, Harvard Medical School
  • National Science and Technology Progress Award First Prize (2014): Core Technology System for Secondary Development of Chinese Patent Medicine and Its Industrialization
  • Ministry of Education Science and Technology Progress Award Second Prize (2017): Key Technology and Application of Screening Platform for Chinese Medicine Efficacy Substances Oriented by Efficacy
  • Tianjin Science and Technology Progress Award First Prize (2011): Key Technology Research and Application of New Chinese Medicine Discovery and Evaluation for Metabolic Diseases
  • Ministry of Education Science and Technology Progress Award Second Prize (2010): Research on the Compatibility Optimization Strategy of Effective Components of Qi and Blood Treatment Formula
  • Zhejiang Province Science and Technology Award Second Prize (2010): Research on Digital Analysis and Discovery Methods of Chinese Medicine Efficacy Substances
  • Zhejiang Province Science and Technology Award Second Prize (2009): Proteomics and Efficacy Substance Basis Research of Shuangdan Formula
  • Zhejiang Province Science and Technology Award Second Prize (2007): Analysis Theory and Application of Group Effect Relationship of Chinese Medicine

Research

Efficacy Substances of Chinese Medicine
High-Content Drug Screening
Modern Chinese Medicine Creation and Secondary Development of Major Varieties
  • Scellseg: a style-aware cell instance segmentation tool with pre-training and contrastive fine-tuning, Dejin Xun, Deheng Chen, Yitian Zhou, Volker M. Lauschke, Rui Wang, Yi Wang, 2022
  • Bilirubin stabilizes the mitochondrial membranes during NLRP3 inflammasome activation, Yufei Li, Hongda Sheng, Ziwei Yan, Bin Guan, Shifa Qiang, Jing Qian, Yi Wang, 2022
  • Si@Ag@PEI Substrate-based SERS Sensor for Rapid Detection of Illegally Adulterated Sulfur Dioxide in Traditional Chinese Medicine, Bo Fan, Yingchao Wang, Zhenhao Li, Dejin Xun, Jian Dong, Xiangwei Zhao, Xiaohui Fan, Yi Wang, 2022
  • Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling, Chen J, Wang Y, Wang S, Zhao X, Zhao L, Wang Y, 2022
  • Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response, Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang, 2022
  • Discovery of herbacetin as a novel SGK1 inhibitor to alleviate myocardial hypertrophy, Shujing Zhang, Yingchao Wang, Min Yu, Ye Shang, Yanxu Chang, Hong Zhao, Yu Kang, Lu Zhao, Lei Xu, Xiaoping Zhao, Dario Difrancesco, Mirko Baruscotti, Yi Wang, 2022
  • Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases, Yunru Yu, Jing Chen, Xiaohui Zhang, Yingchao Wang, Shufang Wang, Lu Zhao, Yi Wang, 2021
  • Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula, Xiaohui Zhang, Yule Wang, Kai Zhang, Hongda Sheng, Yuhan Wu, Huimin Wu, Yingchao Wang, Jianli Guan, Qingfen Meng, Huahuan Li, Zhenhao Li, Guanwei Fan, Yi Wang, 2021
  • Deep-learning-assisted assessment of DNA damage based on Foci images and its application in high-content screening of lead compounds, Xuechun Chen, Dejin Xun, Ruzhang Zheng, Lu Zhao, Yuqing Lu, Jun Huang, Rui Wang, Yi Wang, 2020
  • Sirt3 is a novel target to treat sepsis induced myocardial dysfunction by acetylated modulation of critical enzymes within cardiac tricarboxylic acid cycle, Yinchuan Xu, Shujing Zhang, Jiabing Rong, Yao Lin, Linlin Du, Yi Wang, Zhaocai Zhang, 2020
  • Identification of cryptotanshinone from Tongmai to inhibit thrombosis in zebrafish via regulating oxidative stress and coagulation cascade, Jian Sheng, Qingfen Meng, Zhenzhong Yang, Jianli Guan, Yu Zhao, Jide Zhang, Yingchao Wang, Lu Zhao, Yi Wang, 2020
  • A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular self-assembly, Yu Zhao, Jiawen Zou, Yanyan Song, Jun Peng, Yi Wang, Yong Bi, 2020
  • High content screening identifies licoisoflavone A as a bioactive compound of Tongmaiyangxin Pills to restrain cardiomyocyte hypertrophy via activating Sirt3, Rui Guo, Lingning Liu, Hao Liu, Junhua Zhang, Han Zhang, Yingchao Wang, Mirko Baruscotti, Lu Zhao, Yi Wang, 2020
  • Hollow-Core-Photonic-Crystal-Fiber-Based Miniaturized Sensor for the Detection of Aggregation-Induced-Emission Molecules, Huifang Chen, Qian Jiang, Yu Qiu, Xuechun Chen, Bo Fan, Yi Wang, Dongning Wang, 2019
  • iTRAQ-Based Proteomic Analysis Reveals Recovery of Impaired Mitochondrial Function in Ischemic Myocardium by Shenmai Formula, Yi Wang, Yu Zhao, Wei Jiang, Xiaoping Zhao, Guanwei Fan, Han Zhang, Peiqiang Shen, Jiangmin He, Xiaohui Fan, 2018
  • Fluorescent switchable AIE probe for selective imaging of dipeptidyl peptidase-4 in vitro and in vivo and its application in screening DPP-4 inhibitors, Yi Wang, Xueli Wu, Yiyu Cheng, Xiaoping Zhao, 2016
  • Specific Turn-On Fluorescent Probe with Aggregation-Induced Emission Characteristics for SIRT1 Modulator Screening and Living-Cell Imaging, Yi Wang, Yaqi Chen, Haibo Wang, Yiyu Cheng, Xiaoping Zhao, 2015
Keywords
Chinese Medicine Efficacy Substances Drug Screening High-Content Modern Medicine Creation Development Major Varieties Secondary Development
Related Professors
Xiaoni Fang - Fudan University
Area of Focus
High-Throughput Screening | Drug Screening | Efficiency | Target Proteins | Analysis | Identification | Drug Quality | Control | Technology | Development
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