Professor | 王毅 | 数字化转型顾问

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Name	王毅
Contact Information	zjuwangyi@zju.edu.cn
Language ability	中文, 英文
Province	浙江

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Name

王毅

Contact Information

zjuwangyi@zju.edu.cn

Language ability

中文, 英文

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	本科: 浙江大学, 制药工程博士: 浙江大学, 药物分析全国优秀博士学位论文提名奖浙江省优秀博士论文
Work Experience	教授, 浙江大学药学院副院长, 浙江大学药学院副主任, 浙江大学中药科学与工程学系访问研究员, FDA国立毒理研究中心访问研究员, 哈佛大学医学院
Awards	国家科技进步一等奖 (2014): 中成药二次开发核心技术体系创研及其产业化教育部高等学校科学研究优秀成果奖科学技术进步二等奖 (2017): 以疗效为导向的中药效应物质筛选平台关键技术及其应用天津市科学技术进步奖一等奖 (2011): 治疗代谢性疾病的中药新药发现与评价关键技术研究及应用教育部高等学校科学研究优秀成果奖科学技术进步二等奖 (2010): 气血并治方有效组分辨析及配伍优化策略研究浙江省科学技术奖二等奖 (2010): 中药药效物资源数字化辨析及发掘方法研究浙江省科学技术奖二等奖 (2009): 双丹方蛋白质组学及药效物质基础研究浙江省科学技术奖二等奖 (2007): 中药组效关系辨析理论及其应用

University/Lab Affiliation and Title

浙江大学

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

本科: 浙江大学, 制药工程
博士: 浙江大学, 药物分析
全国优秀博士学位论文提名奖
浙江省优秀博士论文

Work Experience

教授, 浙江大学药学院
副院长, 浙江大学药学院
副主任, 浙江大学中药科学与工程学系
访问研究员, FDA国立毒理研究中心
访问研究员, 哈佛大学医学院

Awards

国家科技进步一等奖 (2014): 中成药二次开发核心技术体系创研及其产业化
教育部高等学校科学研究优秀成果奖科学技术进步二等奖 (2017): 以疗效为导向的中药效应物质筛选平台关键技术及其应用
天津市科学技术进步奖一等奖 (2011): 治疗代谢性疾病的中药新药发现与评价关键技术研究及应用
教育部高等学校科学研究优秀成果奖科学技术进步二等奖 (2010): 气血并治方有效组分辨析及配伍优化策略研究
浙江省科学技术奖二等奖 (2010): 中药药效物资源数字化辨析及发掘方法研究
浙江省科学技术奖二等奖 (2009): 双丹方蛋白质组学及药效物质基础研究
浙江省科学技术奖二等奖 (2007): 中药组效关系辨析理论及其应用

Areas of Focus	中药药效物质高内涵药物筛选现代中药创制与大品种二次开发
Publications	Scellseg: a style-aware cell instance segmentation tool with pre-training and contrastive fine-tuning, Dejin Xun, Deheng Chen, Yitian Zhou, Volker M. Lauschke, Rui Wang, Yi Wang, 2022 Bilirubin stabilizes the mitochondrial membranes during NLRP3 inflammasome activation, Yufei Li, Hongda Sheng, Ziwei Yan, Bin Guan, Shifa Qiang, Jing Qian, Yi Wang, 2022 Si@Ag@PEI Substrate-based SERS Sensor for Rapid Detection of Illegally Adulterated Sulfur Dioxide in Traditional Chinese Medicine, Bo Fan, Yingchao Wang, Zhenhao Li, Dejin Xun, Jian Dong, Xiangwei Zhao, Xiaohui Fan, Yi Wang, 2022 Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling, Chen J, Wang Y, Wang S, Zhao X, Zhao L, Wang Y, 2022 Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response, Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang, 2022 Discovery of herbacetin as a novel SGK1 inhibitor to alleviate myocardial hypertrophy, Shujing Zhang, Yingchao Wang, Min Yu, Ye Shang, Yanxu Chang, Hong Zhao, Yu Kang, Lu Zhao, Lei Xu, Xiaoping Zhao, Dario Difrancesco, Mirko Baruscotti, Yi Wang, 2022 Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases, Yunru Yu, Jing Chen, Xiaohui Zhang, Yingchao Wang, Shufang Wang, Lu Zhao, Yi Wang, 2021 Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula, Xiaohui Zhang, Yule Wang, Kai Zhang, Hongda Sheng, Yuhan Wu, Huimin Wu, Yingchao Wang, Jianli Guan, Qingfen Meng, Huahuan Li, Zhenhao Li, Guanwei Fan, Yi Wang, 2021 Deep-learning-assisted assessment of DNA damage based on Foci images and its application in high-content screening of lead compounds, Xuechun Chen, Dejin Xun, Ruzhang Zheng, Lu Zhao, Yuqing Lu, Jun Huang, Rui Wang, Yi Wang, 2020

Areas of Focus

中药药效物质
高内涵药物筛选
现代中药创制与大品种二次开发

Publications

Scellseg: a style-aware cell instance segmentation tool with pre-training and contrastive fine-tuning, Dejin Xun, Deheng Chen, Yitian Zhou, Volker M. Lauschke, Rui Wang, Yi Wang, 2022
Bilirubin stabilizes the mitochondrial membranes during NLRP3 inflammasome activation, Yufei Li, Hongda Sheng, Ziwei Yan, Bin Guan, Shifa Qiang, Jing Qian, Yi Wang, 2022
Si@Ag@PEI Substrate-based SERS Sensor for Rapid Detection of Illegally Adulterated Sulfur Dioxide in Traditional Chinese Medicine, Bo Fan, Yingchao Wang, Zhenhao Li, Dejin Xun, Jian Dong, Xiangwei Zhao, Xiaohui Fan, Yi Wang, 2022
Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling, Chen J, Wang Y, Wang S, Zhao X, Zhao L, Wang Y, 2022
Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response, Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang, 2022
Discovery of herbacetin as a novel SGK1 inhibitor to alleviate myocardial hypertrophy, Shujing Zhang, Yingchao Wang, Min Yu, Ye Shang, Yanxu Chang, Hong Zhao, Yu Kang, Lu Zhao, Lei Xu, Xiaoping Zhao, Dario Difrancesco, Mirko Baruscotti, Yi Wang, 2022
Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases, Yunru Yu, Jing Chen, Xiaohui Zhang, Yingchao Wang, Shufang Wang, Lu Zhao, Yi Wang, 2021
Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula, Xiaohui Zhang, Yule Wang, Kai Zhang, Hongda Sheng, Yuhan Wu, Huimin Wu, Yingchao Wang, Jianli Guan, Qingfen Meng, Huahuan Li, Zhenhao Li, Guanwei Fan, Yi Wang, 2021
Deep-learning-assisted assessment of DNA damage based on Foci images and its application in high-content screening of lead compounds, Xuechun Chen, Dejin Xun, Ruzhang Zheng, Lu Zhao, Yuqing Lu, Jun Huang, Rui Wang, Yi Wang, 2020

中药药效物质药物筛选高内涵现代药物创制开发大品种二次开发

马国 - 复旦大学

Area of Focus
Ai | 网络药理学 | Pk/Pd | 多组学 | 中药 | 降糖 | 机制 | 药效 | 物质基础 | 研究

章蕴毅 - 复旦大学

Area of Focus
抗炎 | 免疫药理学 | 补体 | 免疫 | 药理学 | 中药 | 药效 | 安全性评价 | 临床研究 | 新药开发

杨振中 - 浙江大学

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