An enzyme-free sensing platform for miRNA detection and in situ imaging in clinical samples based on DNAzyme cleavage-triggered catalytic hairpin assembly, Hechen Wang, Minzhe Shen, Xudan Shen, Jiatong Liu, Wenwen Huang, Xianfeng Jiang, Hui Liu, Su Zeng, Kewang Nan, Sheng Cai, 2024
Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128-3p agomir and Oroxin B: A novel drug delivery approach based on PI3K-AKT and VEGF pathway crosstalk, Hechen Wang, Xudan Shen, Jiatong Liu, Xinlan Zhu, Su Zeng, Sheng Cai, 2024
Design and analysis of self-priming extension DNA hairpin probe for miRNA detection based on a unified dynamic programming framework, Hecheng Wang, Jiatong Liu, Yanyan Fang, Xudan Shen, Hui Liu, Lushan Yu, Su Zeng, Sheng Cai, Jingjing Zhou, Zheyong Li, 2024
A magnetic beads-based ligand fishing method Coupled with UHPLC-QTOF MS for screening and identification of α-glucosidase inhibitors from Houttuynia cordata Thunb, Peixi Zhu, Luxi Zhou, Yuxiu Lin, Yixi Wang, Yu Han, Sheng Cai, 2024
Site-specific detection of circulating tumor DNA methylation in biological samples utilizing phosphorothioated primer-based loop-mediated isothermal amplification, Xudan Shen, Mingcheng Xu, Hechen Wang, Hua Wang, Minzhe Shen, Jadera Talap, Haihong Hu, Su Zeng, Shunxiang Gao, Sheng Cai, 2023
Ultrasensitive detection of serum miRNA biomarkers related to papillary thyroid cancer using ligation-initiated phosphorothioated primer-based loop-mediated isothermal amplification, Jadera Talap, Abdu Ahmed Abdullah AL-maskri, Minzhe Shen, Hui Liu, Xianfeng Jiang, Guizhou Xiao, Lushan Yu, Su Zeng, Cheulhee Jung, Sheng Cai, 2023
A duplex-specific nuclease (DSN) and catalytic hairpin assembly (CHA)-mediated dual amplification method for miR-146b detection, Yu Han, Haihong Hu, Lushan Yu, Su Zeng, Jun Zhe Min, Sheng Cai, 2023
Phosphorothioated and phosphate-terminal dumbbell (PP-TD) probe-based rapid detection of polynucleotide kinase activity, Xianfeng Jiang, Xudan Shen, Jadera Talap, Dan Yang, Su Zeng, Hui Liu, Sheng Cai, 2022
RT-LAMP assay combining multi-fluorescent probes for SARS-CoV-2 RNA detection and variant differentiation, Jadera Talap, Minzhe Shen, Lushan Yu, Su Zeng, Sheng Cai, 2022
A self-assembly amplification strategy for ultra-sensitive detection of microRNA based on phosphorothioated probes, Abdu Ahmed Abdullah AL-maskri, Guangbo Jin, Yang Li, Jadera Talap, Marwan Almoiliqy, Chowdhury Apu, Su Zeng, Ying Zhou, Sheng Cai, 2022
A sensitive isothermal fluorescence biosensor for microRNA detection coupling primer exchange reaction with catalytic hairpin assembly, Jiatong Liu, Minzhe Shen, Jadera Talap, Xudan Shen, Zihan Song, Haihong Hu, Su Zeng, Sheng Cai, 2022
A Novel Helper qPCR Assay for the Detection of miRNA Using Target/Helper Template for Primer Formation, Xianfeng Jiang, Jiahui Wang, Xudan Shen, Jadera Talap, Yang Yang, Dan Yang, Guizhou Xiao, Sheng Cai, 2022
MUC1 detection and in situ imaging method based on aptamer conformational switch and hybridization chain reaction, Zihan Song, Yun Zhou, Minzhe Shen, Dong Zhao, Haihong Hu, Su Zeng, Lianli Sun, Sheng Cai, 2022
Rolling Circle and Loop Mediated Isothermal Amplification Strategy for Ultrasensitive miRNA Detection, Zheng Cao, Xianfeng Jiang, Guizhou Xiao, Mingcheng Xu, Hui Liu, Sheng Cai, 2021
Recent advances in therapeutic nucleic acids and their analytical methods, Jadera Talap, Jing Zhao, Minzhe Shen, Zihan Song, Hui Zhou, Yu Kang, Lianli Sun, Lushan Yu, Su Zeng, Sheng Cai, 2021
Reverse transcription-based loop-mediated isothermal amplification strategy for real-time miRNA detection with phosphorothioated probes, Abdu Ahmed Abdullah AL-maskri, Jiawei Ye, Jadera Talap, Haihong Hu, Lianli Sun, Lushan Yu, Sheng Cai, Su Zeng, 2020
Recent advances and perspectives of nucleic acid detection for coronavirus, Minzhe Shen, Ying Zhou, Jiawei Ye, Abdu Ahmed Abdullah AL-maskri, Yu Kang, Su Zeng, Sheng Cai, 2020
A Novel Helper qPCR System for Platinum Detection via Pt-DNA Coordination, Sheng Cai, Dan Yang, Xueke Tian, Jiawei Ye, Mingcheng Xu, Abdu Ahmed Abdullah AL-maskri, Cheulhee Jung, Su Zeng, 2019
Functionalized aptamer with an antiparallel G-quadruplex: Structural remodeling, recognition mechanism, and diagnostic applications targeting CTGF, Shunxiang Gao, Wei Hu, Xin Zheng, Sheng Cai, Jihong Wu, 2019
Ultrasensitive detection of miRNA via one-step rolling circle-quantitative PCR (RC-qPCR), Mingcheng Xu, Jiawei Ye, Dan Yang, Abdu Ahmed Abdullah AL-maskri, Haihong Hu, Cheulhee Jung, Sheng Cai, Su Zeng, 2019
Research advances in the detection of miRNA, Jiawei Ye, Xueke Tian, Mingcheng Xu, Sheng Cai, Su Zeng, 2019
A chemiluminescence resonance energy transfer strategy and its application for detection of platinum ions and cisplatin, Sheng Cai, Ying Zhou, Jiawei Ye, Ruizhe Chen, Lianli Sun, Jianzhong Lu, Cheulhee Jung, Su Zeng, 2019
Enantioselective Reduction of α, β-Unsaturated Ketones and Aryl Ketones by Perakine Reductase, Sheng Cai, Nana Shao, Yuanyuan Chen, Anbang Li, Jie Pan, Huajian Zhu, Hongbin Zou, Su Zeng, Lianli Sun, Jinhao Zhao, 2019
A conformational switch‐based aptasensor for the chemiluminescence detection of microRNA, Sheng Cai, Jiawei Ye, Abdu Ahmed Abdullah AL-maskri, Lianli Sun, Su Zeng, 2019
Phosphorothioated Primers Lead to Loop-Mediated Isothermal Amplification at Low Temperatures, Sheng Cai, Cheulhee Jung, Sanchita Bhadra, Andrew D Ellington, 2018
Portable platform for rapid in-field identification of human fecal pollution in water, Yu Jiang Sherry, Timothy E Riedel, Jessica A Popoola, Barrett R Morrow, Sheng Cai, Andrew D. Ellington, Sanchita Bhadra, 2018
Platinum (II)-Oligonucleotide Coordination Based Aptasensor for Simple and Selective Detection of Platinum Compounds, Sheng Cai, Xueke Tian, Lianli Sun, Haihong Hu, Shirui Zheng, Huidi Jiang, Lushan Yu, Su Zeng, 2015
Label-free technology for the amplified detection of microRNA based on the allosteric hairpin DNA switch and hybridization chain reaction, Sheng Cai, Zhijuan Cao, Choiwan Lau, Jianzhong Lu, 2014
Sensitive chemiluminescence aptasensor based on exonuclease-assisted recycling amplification, Sheng Cai, Yanhua Sun, Choiwan Lau, Jianzhong Lu, 2013
“Turn-On” Chemiluminescence Sensor for the Highly Selective and Ultrasensitive Detection of Hg2+ Ions Based on Interstrand Cooperative Coordination and Catalytic Formation of Gold Nanoparticles, Sheng Cai, Choiwan Lau, Jianzhong Lu, 2011
Turn-on Aptameric System for Simple and Selective Detection of Protein via Base Stacking-dependent DNA Hybridization Event, Sheng Cai, Choiwan Lau, Jianzhong Lu, 2011
Ultrasensitive and selective DNA detection by hydroxylamine assisted gold nanoparticle amplification, Sheng Cai, Liang Xin, Choiwan Lau, Jianzhong Lu, Xueji Zhang, 2011
Aptameric system for the highly selective and ultrasensitive detection of protein in human serum based on non-stripping gold nanoparticles, Yanhua Sun, Sheng Cai, Zhijuan Cao, Choiwan Lau, Jianzhong Lu, 2011
Sequence-Specific Detection of Short-Length DNA via Template-Dependent Surface-Hybridization Events, Sheng Cai, Choiwan Lau, Jianzhong Lu, 2010
Highly sensitive non-stripping gold nanoparticles-based chemiluminescent detection of DNA hybridization coupled to magnetic beads, Sheng Cai, Liang Xin, Choiwan Lau, Jianzhong Lu, 2010
Hydroxylamine- amplified gold nanoparticles for the homogeneous detection of sequence-specific DNA, Aiping Fan, Sheng Cai, Zhijuan Cao, Choiwan Lau, Jianzhong Lu, 2010
Area of Focus
Drug Metabolism | Pharmacokinetics | Drug Transporters | Epigenetics | Biomarkers | Drug Resistance | Tumor Cells | Humanized Models | Analytical Pharmacology | Drug Enzymes