Zhejiang Provincial Science and Technology Second Prize (2012): Chiral Drug Analysis and Chiral Drug Metabolism
Zhejiang Provincial Science and Technology Second Prize (2010): Establishment and Application of Traditional Chinese Medicine Metabolism Analysis Technology Platform
Research
Drug Metabolism and Drug Transport Drug Analysis
Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice, Mingyang Chen, Mengru Bai, Yaodong Yi, Shuanghui Lu, Jun Luo, Ping Li, Hengbin Zhang, Huidi Jiang, Hui Zhou, 2022
Estradiol reduced 5-HT reuptake by downregulating the gene expression of Plasma Membrane Monoamine Transporter (PMAT, Slc29a4) through estrogen receptor beta and the MAPK/ERK signaling pathway, Yong Gu, Nanxin Zhang, Shujie Zhu, Shuanghui Lu, Huidi Jiang, Hui Zhou, 2022
Organic cation transporter 1 and 3 contribute to the high accumulation of dehydrocorydaline in the heart, Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zhou, 2020
L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy, Cui Li, Liping Li, Yaodong Yi, Wei Wang, Jingqun Yuan, Fuqing Tan, Danbo Fang, Su Zeng, Hui Zhou, Huidi Jiang, 2020
Local and systemic immune dysregulation alters glioma growth in hyperglycemic mice, Ian Y. Zhang, Hui Zhou, Huili Liu, Leying Zhang, Hang Gao, Shunan Liu, Yanyan Song, Darya Alizadeh, Hongwei Holly Yin, Raju Pillai, Behnam Badie, 2020
Dehydrocorydaline induced antidepressant-like effect in a chronic unpredictable mild stress mouse model via inhibiting uptake-2 monoamine transporters, Lisha Jin, Sisi Zhou, Shujie Zhu, Shaowei Lei, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zhou, 2019
Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis, Ting Jiang, Yingqiong Zhang, Mengru Bai, Ping Li, Wei Wang, Mingyang Chen, Zhiyuan Ma, Su Zeng, Hui Zhou, Huidi Jiang, 2019
Luteolin shows antidepressant-like effect by inhibiting and regulating plasma membrane monoamine transporter (PMAT, Slc29a4), Shujie Zhu, Shaowei Lei, Sisi Zhou, Lisha Jin, Su Zeng, Huidi Jiang, Hui Zhou, 2019
Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice, Siyuan Sun, Sisi Zhou, Shaowei Lei, Shujie Zhu, Kai Wang, Huidi Jiang, Hui Zhou, 2019
Development and validation of a HPLC-ESI-MS/MS method for simultaneous quantification of fourteen alkaloids in mouse plasma after oral administration of the extract of Corydalis yanhusuo tuber: Application to pharmacokinetic study, Weijuan Du, Lisha Jin, Liping Li, WeiWang, Su Zeng, Huidi Jiang, Hui Zhou, 2018
The bioactive components of Coreopsis tinctoria (Asteraceae) capitula: Antioxidant activity in vitro and profile in rat plasma, Zhiyuan Ma, Shirui Zheng, Haixia Han, Jie Meng, Xi Yang, Su Zeng, Hui Zhou, Huidi Jiang, 2016
Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity, Qi Shen, Minjuan Zuo, Li Ma, Ye Tian, Lu Wang, Huidi Jiang, Quan Zhou, Hui Zhou, Lushan Yu, Su Zeng, 2014
Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine, Siyuan Sun, Kai Wang, Hongmei Lei, Liping Li, Meijuan Tu, Su Zeng, Hui Zhou, Huidi Jiang, 2014
In vitro characterization of ABC transporters involved in the absorption and distribution of liensinine and its analogs, Lushan Yu, Qi Shen, Quan Zhou, Huidi Jiang, Huichang Bi, Min Huang, Hui Zhou, Su Zeng, 2013
Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity, Meijuan Tu, Siyuan Sun, Kai Wang, Xueying Peng, Ruihan Wang, Liping Li, Su Zeng, Hui Zhou, Huidi Jiang, 2013
The interaction between human breast cancer resistance protein (BCRP) and five bisbenzylisoquinoline alkaloids, Ye Tian, Sainan Qian, Yan Jiang, Qi Shen, Jiang Zheng, Hui Zhou, Su Zeng, 2013
Stereoselective Interaction between tetrahydropalmatine enantiomers and CYP enzymes in human liver microsomes, Si-Yuan Sun, Yu-Qing Wang, Li-Ping Li, Lu Wang, Su Zeng, Hui Zhou, Huidi Jiang, 2013
Characterization of phenolics of Sarcandra glabra by non-targeted high-performance liquid chromatography fingerprinting and following targeted electrospray ionisation tandem mass spectrometry/time-of-flight mass spectrometry analyses, Hui Zhou, Junling Liang, Da Lv, Yinfei Hu, Yan Zhu, Jinping Si, Shihua Wu, 2013
Keywords
Drug MetabolismDrug TransportPharmacokineticsToxicologyBiotransformationEnzyme InductionDrug-Drug InteractionsPharmacodynamicsBioavailabilityTherapeutic Drug Monitoring
Area of Focus
Pharmacogenomics | Personalized Medicine | Genetic Polymorphism | Drug Metabolism | Clinical Pharmacokinetics | Pharmacodynamics | Therapeutic Drug Monitoring | End-Stage Renal Disease | Drug Resistance | Cancer Pharmacology
