Areas of Focus
- Natural and Biomimetic Drugs
Work Experience
- 2008-07 to present - Peking University Health Science Center, School of Pharmaceutical Sciences, State Key Laboratory of Natural and Biomimetic Drugs - Professor
- 2002-09 to 2008-06 - Peking University Health Science Center, School of Pharmaceutical Sciences, State Key Laboratory of Natural and Biomimetic Drugs - Associate Professor
- 1998-08 to 2000-04 - Peking University Health Science Center, Department of Medicinal Chemistry - Associate Professor
- 1987-08 to 1995-07 - Peking University Health Science Center, Department of Organic Chemistry - Lecturer
Academic Background & Achievements
- 1995-08 to 1998-07 PhD in Medicinal Chemistry: Peking University Health Science Center
- 1982-08 to 1987-07 Bachelor's in Pharmacy: Peking University Health Science Center
Publications
- Modified ASO conjugates encapsulated with cytidinyl/cationic lipids exhibit more potent and longer-lasting anti-HCC effects, Yufei Pan; Jing Guan; Yujing Gao; Yuejie Zhu; Huantong Li; Hua Guo; Qianyi He; Zhu Guan; Zhenjun Yang, 2023
- Novel formulation of c-di-GMP with cytidinyl/cationic lipid reverses T cell exhaustion and activates stronger anti-tumor immunity, Xiaotong Yu; Jing Yu; Hong Dai; Chenyun Deng; Xudong Sun; Sijie Long; Zhujun Jiang; Hongyan Jin; Zhu Guan; Zhenjun Yang, 2022
- Feasibility of cRGD conjugation at 5'-antisense strand of siRNA by phosphodiester linkage extension, Zhou, Xinyang; Pan, Yufei; Yu, Lijia; Wu, Jing; Li, Zheng; Li, Huantong; Guan, Zhu; Tang, Xinjing; Yang, Zhenjun, 2021
- Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo, Ma, Yuan; Zhao, Wenting; Li, Yiding; Pan, Yufei; Wang, Shuhe; Zhu, Yuejie; Kong, Lingxuan; Guan, Zhu; Wang, Jiancheng; Zhang, Lihe; Yang, Zhenjun, 2019
- Annealing novel nucleobase-lipids with oligonucleotides or plasmid DNA based on H-bonding or pi-pi interaction: Assemblies and transfections, Ma, Yuan; Zhu, Yuejie; Wang, Chao; Pan, Delin; Liu, Shuang; Yang, Mengyi; Xiao, Zhangping; Yang, Xiantao; Zhao, Wenting; Zhou, Xinyang; Li, Yiding; Pan, Yufei; Sun, Jing; Wang, Shuhe; Guan, Zhu; Zhang, Lihe; Yang, Zhenjun, 2018