1986 - Bachelor's Degree in Science: Shandong University
1989 - Master's Degree in Science: Shandong University
1998-2000 - Research and Study: University of Regensburg, Germany
Published over 80 papers in domestic and international journals
Authored or co-authored 6 textbooks or monographs
Translated 1 monograph
Contributed to 4 textbooks
Received 9 national invention patents
1989 - Present - Beijing Medical University, School of Pharmacy - Faculty Member
2000 - Present - Peking University, School of Pharmacy - Associate Professor
Research
Physical Pharmaceutics New Nano Carrier Systems and Targeted Drug Delivery Functional Polymer Materials and Intelligent Drug Delivery Systems Drug Polymorphism
Self-assembled nanoparticles from vitamin E succinate-based amphiphilic polymers for effective intestinal delivery of paclitaxel and their transcellular transport mechanisms and intracellular trafficking routes, Xiaoyou Qu, Yang Zou, Yuanhang Zhou, Yan Liu*, et al., 2018
Mechanisms of pH-sensitivity and cellular internalization of PEOz-b-PLA micelles with varied hydrophilic/hydrophobic ratios and intracellular trafficking routes and fate of the copolymer, Dishi Wang, Yanxia Zhou, Xinru Li, Yan Liu*, et al., 2017
Concurrently suppressing multidrug resistance and metastasis of breast cancer by co-delivery of paclitaxel and honokiol with polymeric micelles, Ziqi Wang, Xinru Li, Dishi Wang, Yan Liu*, et al., 2017
Preparation and characterization of pH-responsive polymeric micelles based on poly(2-ethyl-2-oxazoline)-vitamin E succinate for paclitaxel delivery, Xiaoyou Qu, Yang Zou, Yuanhang Zhou, Yan Liu*, et al., 2017
PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking, Yajie Gao, Yanfang Li, Yushu Li, Yan Liu*, et al., 2015
Poly(2-ethyl-2-oxazoline)-doxorubicin conjugate-based dual endosomal pH-sensitive micelles with enhanced antitumor efficacy, Jinwen Li, Yanxia Zhou, Chengwei Li, Yan Liu*, et al., 2015
pH-responsive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(D,L-lactide) for tumor-targeting and controlled delivery of doxorubicin and P-gp inhibitor, Yong Zhao, Yanxia Zhou, Dishi Wang, Yan Liu*, et al., 2015
Endosomal pH-responsive polymer-based dual-ligand-modified micellar nanoparticles for tumor targeted delivery and facilitated intracellular release of paclitaxel, Yajie Gao, Chao Zhang, Yanxia Zhou, Yan Liu*, et al., 2015
Bovine serum albumin nanoparticles for delivery of tacrolimus to reduce its kidney uptake and functional nephrotoxicity, Lei Zhao, Yanxia Zhou, Yajie Gao, Yan Liu*, et al., 2015
Enhanced antitumor efficacy by cyclic RGDyK-conjugated and paclitaxel-loaded pH-responsive polymeric micelles, Yajie Gao, Yanxia Zhou, Lei Zhao, Yan Liu*, et al., 2015
The Inhibition Mechanism of P-glycoprotein Mediated Efflux by mPEG-PLA and Influence of PLA Chain Length on P-glycoprotein Inhibition Activity, Wenjing Li, Xinru Li, Yajie Gao, Yan Liu*, et al., 2014
Enhanced topical delivery of tetrandrine by ethosomes for treatment of arthritis, Chao Fan, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2013
The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier, Na Li, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2012
In vitro and in vivo evaluation of a simple microemulsion formulation for propofol, Guiling Li, Yating Fan, Xinru Li, Yan Liu*, et al., 2012
Preparation and in vitro evaluation of tacrolimus loaded ethosomes, Guiling Li, Chao Fan, Xinru Li, Yan Liu*, et al., 2012
Tacrolimus-loaded ethosomes: Physicochemical characterization and in vivo evaluation, Guiling Li, Yating Fan, Chao Fan, Yan Liu*, et al., 2012
Chitosan-based thermosensitive hydrogel as a promising ocular drug delivery system: preparation, characterization and in vivo evaluation, Xingwei Chen, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2012
Synthesis, characterization and biocompatibility of poly(2-ethyl-2-oxazoline)-poly(D,L-lactide)-poly(2-ethyl-2-oxazoline) hydrogels, Xiaoning Wang, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2011
An oil-free microemulsion for intravenous delivery of diallyl trisulfide: Formulation and evaluation, Xinru Li, Yuanting Yue, Yanxia Zhou, Yan Liu*, et al., 2011
Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol, Xinru Li, Yanhui Zhang, Yating Fan, Yan Liu*, et al., 2011
Improved intestinal delivery of salmon calcitonin by water-in-oil microemulsions, Yating Fan, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2011
Cyclosporine A-loaded poly(ethylene glycol)-b-poly(D,L-lactic acid) micelles: preparation, in vitro and in vivo characterization and transport mechanism across the intestinal barrier, Yanhui Zhang, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2010
Novel nanoscaled polyion complex micelles for targeted delivery of recombinant hirudin to platelets based on cationic copolymer, Wang Fei, Li Xinru, Zhou Yanxia, Yan Liu*, et al., 2010
Novel mixed polymeric micelles for enhancing delivery of anticancer drug and overcoming multidrug resistance in tumor cell lines simultaneously, Xinru Li, Pingzhu Li, Yan Liu*, et al., 2010
Development of patch and spray formulations for enhancing topical delivery of sinomenine hydrochloride, Xinru Li, Xiaoyan Li, Yanxia Zhou, Yan Liu*, et al., 2010
Preparation and evaluation of poly(ethylene glycol)–poly(Lactide) micelles as nanocarriers for oral Delivery of cyclosporine A, Yanhui Zhang, Xinru Li, Yanxia Zhou, Yan Liu*, et al., 2010
Development of silymarin self-microemulsifying drug delivery system with enhanced oral bioavailability, Xinru Li, Quan Yuan, Yanqing Huang, Yan Liu*, et al., 2010
Improved absorption of salmon calcitonin by ultraflexible liposomes through intranasal delivery, Ming Chen, Xin-Ru Li, Yan-Xia Zhou, Yan Liu*, et al., 2009
Novel polyion complex micelles for liver-targeted delivery of diammonium glycyrrhizinate: in vitro and in vivo characterization, Kewei Yang, Xinru Li, Zhuoli Yang, Yan Liu*, et al., 2009
Self-assembly and characterization of Pluronic P105 micelles for liver-targeted delivery of silybin, Xinru Li, Yanqing Huang, Xingwei Chen, Yanxia Zhou, Yan Liu*, et al., 2009
Self-assembled polymeric micellar nanoparticles as nanocarriers for poorly soluble anticancer drug ethaselen, Xinru Li, Zhuoli Yang, Kewei Yang, Yan Liu*, et al., 2009
Amphotericin B-loaded poly(ethylene glycol)-poly(lactide) micelles: preparation, freeze-drying and in vitro release, Zhuoli Yang, Xinru Li, Kewei Yang, Yan Liu*, 2008
Keywords
Physical PharmaceuticsNano Carrier SystemsTargeted Drug DeliveryFunctional PolymersIntelligent Drug DeliveryDrug PolymorphismNanoparticlesPolymeric MicellesPh-ResponsiveIntracellular Trafficking
