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Jian-Hui Liang
Pharmaceutical Sciences
Peking University
Beijing
Language: Chinese, English
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Neuropsychopharmacology Behavioral Plasticity Neurobiological Mechanisms Traditional Chinese Medicine Alcohol Pharmacological Activity Screening Evaluation Depression Anxiety Animal Models
Areas of Focus
  • Neuropsychopharmacology
  • Behavioral plasticity neurobiological mechanisms
  • Screening and evaluation of alcohol pharmacological activity of traditional Chinese medicine components
  • Application and mechanism research of new animal models of depression and anxiety comorbidity
Academic Background & Achievements
  • 1978-09 to 1983-07 Bachelor of Medicine: University of South China
  • 1995-07 Doctor of Medicine: Peking University Institute of Mental Health
  • 1995-09 to 1998-02 Postdoctoral in Pharmacy: Academy of Military Medical Sciences
  • Founder and Regular Member: Asian Pacific Society for Alcohol and Addiction Research (APSAAR)
  • Secretary-General: Neuropsychopharmacology Professional Committee of the Chinese Pharmacological Society
  • Deputy Director: Neuropsychopharmacology Professional Committee of Beijing Pharmacological Society
  • Associate Editor: Metabolic Brain Disease
Publications
  • Context- and time-dependent neurobiological and behavioral sensitization induced by a single morphine exposure in mice, Qin WJ, Wang YT, Li PM, Wang XX, Li JX, Noori HR, Bernardi RE, Liang JH*, Zhang XL*, 2016
  • Role of phosphodiesterase 4-mediated cyclic AMP signaling in pharmacotherapy for substance dependence, Wen RT, Feng WY, Liang JH*, Zhang HT*, 2015
  • An-jun-ning, a traditional herbal formula, attenuates spontaneous withdrawal symptoms via modulation of the dopamine system in morphine-dependent rats, Gao JL, Tu SA, Liu J, Zhang JM, Huang Y, Han M, Liang JH*, 2014
  • The glycine receptor antagonist brucine decreases ethanol intake and preference in alcohol-preferring Fawn-Hooded rats, Yu-ling LI, Qing LIU, Qi GONG, Jun-xu LI, Shou-peng WEI, Yan-ting WANG, Hui LIANG, Min ZHANG, Li JING, Zheng YONG, Andrew J. LAWRENCE and Jian-hui LIANG*, 2014
  • Comparison of single versus repeated methamphetamine injection induced behavioral sensitization in mice, Jing L, Zhang M, Li JX, Huang P, Liu Q, Li YL, Liang H, Liang JH*, 2014
  • Chaperone heat shock protein 70 in nucleus accumbens core: a novel biological target of behavioural sensitization to morphine in rats, Yan-Ting Wang, Wang-Jun Qin, Qing Liu, Yu-Ling Li, Hui Liang, Feng Chen, Andrew J. Lawrence and Jian-Hui Liang*, 2014
  • Molecular chaperone heat shock protein 70 participates in the labile phase of the development of behavioural sensitization induced by a single morphine exposure in mice, Qin WJ, Wang YT, Zhang M, Wen RT, Liu Q, Li YL, Chen F, Lawrence AJ, Liang JH*, 2013
  • The Phosphodiesterase-4 (PDE4) Inhibitor Rolipram Decreases Ethanol Seeking and Consumption in Alcohol-Preferring Fawn-Hooded Rats, Wen RT, Zhang M, Qin WJ, Liu Q, Wang WP, Lawrence AJ, Zhang HT, Liang JH*, 2012
  • Tramadol induces conditioned place preference in rats: Interactions with morphine and buprenorphine, Zhang M, Jing L, Liu Q, Wen RT, Li JX, Li YL, Gong Q, Liang JH*, 2012
  • Septal Nuclei Critically Mediate the Development of Behavioral Sensitization to a Single Morphine Injection in Rats, Qing Liu, Min Zhang, Wang-Jun Qin, Yan-Ting Wang, Li Jing, Jun-Xu Li, Andrew J. Lawrence, Jian-Hui Liang*, 2012
  • Morphine attenuates frustration-like behavior induced by sucrose reward deprivation in rats, Qing Liu, Wang-Jun Qin, Min Zhang, Yan-Ting Wang, Li Jing, Jun-Xu Li, Jian-Hui Liang*, 2011
  • Effect of the histone deacetylase inhibitors on behavioural sensitization to a single morphine exposure in mice, Jing L, Luo J, Zhang M, Qin WJ, Li YL, Liu Q, Wang YT, Lawrence AJ, Liang JH*, 2011
  • Traditional Chinese medicine for treatment of alcoholism: from ancient to modern, Qing Liu, Andrew J. Lawrence, Jian-hui Liang*, 2011
  • Transcription and protein synthesis inhibitors reduce the induction of behavioural sensitization to a single morphine exposure and regulate Hsp70 expression in the mouse nucleus accumbens, Luo J, Jing L, Qin WJ, Zhang M, Lawrence AJ, Chen F, Liang JH*, 2011
  • Systemic Administration of Arecoline Reduces Ethanol-Induced Sleeping Through Activation of Central Muscarinic Receptor in Mice, Sun YP, Liu Q, Luo J, Guo P, Chen F, Lawrence AJ, Liang JH*, 2010
  • The GABAB receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats, Jian-Hui Liang, Feng Chen, Michael S. Cowen, Fiona Y. Carroll, Duncan Crawford, Philip M. Beart, Andrew J. Lawrence*, 2006
  • Potentiating effect of tramadol on methamphetamine-induced behavioral sensitization in mice, Jian-Hui Liang, Keng Wang, Hong-Lei Sun, and Rong Han, 2006
  • Different effects of valproate on methamphetamine- and cocaine-induced behavioral sensitization in mice, Li JX, Han R, Deng YP, Chen SQ, Liang JH*, 2005
  • A new buprenorphine analogy, thenorphine, inhibits morphine-induced behavioral sensitization in mice, Wen-Li Zhao, Ze-Hui Gong, Jian-Hui Liang*, 2004
  • Effects of carbamazepine on morphine-induced behavioral sensitization in mice, Li JX, Zhao WL, Liang JH*, 2004
  • Valproate prevents the induction, but not the expression of morphine sensitization in mice, Li JX, Zhang Q, Liang JH*, 2004
  • L-type calcium channel blockers enhance 5-HTP-induced antinociception in mice, Liang JH*, Li JX, Wang XH, Chen B, Lu Y, Zhang P, Han R, Ye XF, 2004
  • Nerve growth factor protects R2 cells against neurotoxicity induced by methamphetamine, Zhou JL, Liang JH*, Zheng JW, Li CL, 2004
  • Calmodulin inhibitor trifluoperazine attenuates the development and expression of morphine-induced conditioned place preference in rats, Ye XF, Lu Y, Zhang P, Liang JH*, 2004
  • L-type Ca (2+) channel blockers inhibit the development but not the expression of sensitization to morphine in mice, Zhang Q, Li JX, Zheng JW, Liu RK, Liang JH*, 2003
  • Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice, Liang JH*, Wang XH, Liu RK, Sun HL, Ye XF, Zheng JW, 2003
  • Tramadol reduces the 5-HTP-induced head-twitch response in mice via the activation of mu and kappa opioid receptors, Sun HL, Zheng JW, Wang K, Liu RK, Liang JH*, 2003
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