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Liqin Zhang
Pharmaceutical Sciences
Peking University
Beijing
Language: Chinese, English
Nucleic Acid Probes
Drug Analysis
Bioanalytical Strategies
Pharmacological Mechanism
Functional Nucleic Acids
Drug Design
Drug Development
New Drug Targets
Multifunctional Probes
Physiological Regulation
Areas of Focus
- Construction and Drug Analysis Applications of Multifunctional Nucleic Acid Probes
- Bioanalytical Strategies and Physiological Pharmacological Mechanism Regulation
- Design and Development of Functional Nucleic Acid Drugs
- Discovery of New Drug Targets and Drug Development
Work Experience
- 2020-2021 - Thermo Fisher Scientific - Senior Scientist
- 2021-Present - Peking University School of Pharmaceutical Sciences - Distinguished Researcher, Group Leader, Doctoral Supervisor
Academic Background & Achievements
- 2005-2011 Master's Degree: Peking University School of Pharmaceutical Sciences
- 2011-2016 Ph.D.: University of Florida, Department of Chemistry/College of Medicine Cancer Center
- 2018-2019 Postdoctoral: Stanford University School of Medicine
Publications
- Aptamer Properties, Functions, and Applications, Weihong Tan, Zilong Zhao, Liqin Zhang, 2022
- An Aptamer‐Nanotrain Assembled from 6‐Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells, Liqin Zhang, Sai Wang, Zunyi Yang, Shuichi Hoshika, Sitao Xie, Jin Li, Xigao Chen, Shuo Wan, Long Li, Steven A Benner, Weihong Tan, 2020
- A Light-Up Strategy with Aggregation-Induced Emission for Identification of HIV-Ι RNA-Binding Small Molecules, Jun Li, Yao-Yao Fan, Man Wang, Hui-Ling Duan, Jing Zhang, Fuquan Dang, Liqin Zhang, Zhi-Qi Zhang, 2020
- Engineering Aptamer with Enhanced Affinity by Triple Helix-Based Terminal Fixation, Lianhui Zhao, Xiaoyan Qi, Xiaochen Yan, Yunfei Huang, Xingguo Liang, Liqin Zhang, Sai Wang, Weihong Tan, 2019
- Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology, Liqin Zhang, Shuo Wan, Ying Jiang, Yanyue Wang, Ting Fu, Qiaoling Liu, Zhijuan Cao, Liping Qiu, Weihong Tan, 2017
- DNA Nanoassembly on Exosome Membrane Surfaces for Enhanced Fluorescent Detection, Shuo Wan, Liqin Zhang, Sai Wang, Sena Cansiz, Hui Zhang, Yuan Liu, Cheng Cui, Weihong Tan, 2017
- Aptasensor with Expanded Nucleotide using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes, Sai Wang, Liqin Zhang, Shuo Wan, Sena Cansiz, Yuan Liu, Ren Cai, Cheng-Yi Hong, I-Ting Teng, Muling Shi, Yuan Wu, Yiyang Dong, Weihong Tan, 2017
- Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution Give Aptamers against Glypican-3-Overexpressing Tumor Cells, Liqin Zhang, Zunyi Yang, Thu Le Trinh, I-Ting Teng, Sai Wang, Kevin M Bradley, Shuichi Hoshika, Qunfeng Wu, Sena Cansiz, Diane J Rowold, Christopher McLendon, Myong-Sang Kim, Yuan Wu, Cheng Cui, Yuan Liu, Weijia Hou, Kimberly Stewart, Shuo Wan, Chen Liu, Steven A. Benner, Weihong Tan, 2016
- Evolution of Functional Six-Nucleotide DNA, Liqin Zhang, Zunyi Yang, Kwame Sefah, Kevin M Bradley, Shuichi Hoshika, Myong-Jung Kim, Hyo-Joong Kim, Guizhi Zhu, Elizabeth Jimenez, Sena Cansiz, I-Ting Teng, Carole Champanhac, Christopher McLendon, Chen Liu, Wen Zhang, Dietlind L Gerloff, Zhen Huang, Weihong Tan, Steven A Benner, 2015
- Self-Assembled DNA Immuno-Nanoflowers as Multivalent CpG Nanoagents, Liqin Zhang, Guizhi Zhu, Lei Mei, Cuichen Wu, Liping Qiu, Cheng Cui, Yuan Liu, I-Ting Teng, Weihong Tan, 2015
- Unnatural Nucleic Acids for Aptamer Selection, Liqin Zhang, 2015
- DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency, Sena Cansiz, Liqin Zhang, Cuichen Wu, Yuan Wu, I-Ting Teng, Weijia Hou, Yanyue Wang, Shuo Wan, Ren Cai, Chen Jin, Qiaoling Liu, Weihong Tan, 2015
- Biotransformation of Phlorizin by Human Intestinal Flora and Inhibition of Biotransformation Products on Tyrosinase Activity, Li-Qin Zhang, Xiu-Wei Yang, You-Bo Zhang, Ya-Ya Zhai, Wei Xu, Bo Zhao, Dai-Lin Liu, Hong-Jian Yu, 2012
- Intestinal Permeability of Liquiritin and Isoliquiritin in the Caco-2 cell Monolayer Model, Li-Qin Zhang, Ying-Dong Huang, Xiu-Wei Yang, 2010
