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Zhuan Zhou
Life Sciences / Medical / Biology
Peking University
Beijing
Language: English, Chinese, German
Secretion
Molecular Mechanisms
Cellular Mechanisms
Neuroscience
Biophysics
Neurodegenerative Diseases
Synaptic Transmission
Neurotransmitters
Ion Channels
Signal Transduction
Areas of Focus
- Molecular and Cellular Mechanisms of Secretion
Work Experience
- 1990.11-1993.2 Max Planck Institute for Biophysical Chemistry, Postdoctoral Researcher
- 1992.3-1992.9 Max Planck Institute for Biophysical Chemistry, Visiting Researcher
- 1993.1-1993.6 Max Planck Institute for Medical Research, Visiting Researcher
- 1993.2-1995.11 Washington University in St. Louis, Lecturer
- 1995.11-1997.8 Loyola University Chicago, Research Assistant Professor
- 1993.4-2000.5 Huazhong University of Science and Technology, Associate Professor (1993), Professor (1995)
- 1999.10-2004.12 Chinese Academy of Sciences, Director of the Laboratory of Cellular Biophysics, Researcher
- 2005.1-present Peking University, Senior Researcher, Professor
Academic Background & Achievements
- 1979-1984 Bachelor's Degree: Tongji University, Electronic Instruments
- 1986-1990 Doctoral Degree: Huazhong University of Science and Technology, Biomedical Engineering
- National Outstanding Youth Fund
- CAS 'Hundred Talents Program'
- National Excellent Doctoral Dissertation Supervisor
- American 'Li Foundation Award'
- First Prize of the Ministry of Education's 'Outstanding Scientific Research Achievement Award in Natural Science'
Publications
- Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice., Wang L, Gao M, Wang Q, Sun L, Younus M, Ma S, Liu C, Shi L, Lu Y, Zhou B, Sun S, Chen G, Li J, Zhang Q, Zhu F, Wang C, Zhou Z., 2023
- Ca2+ -independent transmission at the central synapse formed between dorsal root ganglion and dorsal horn neurons., Wang Y, Huang R, Chai Z, Wang C, Du X, Hang Y, Xu Y, Li J, Jiang X, Wu X, Qiao Z, Li Y, Liu B, Zhang X, Cao P, Zhu F, Zhou Z., 2022
- Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation., Lin Z, Li Y, Hang Y, Wang C, Liu B, Li J, Yin L, Jiang X, Du X, Qiao Z, Zhu F, Zhang Z, Zhang Q, Zhou Z., 2022
- Cocaine increases quantal norepinephrine secretion through NET-dependent PKC activation in locus coeruleus neurons., Zhu F, Liu L, Li J, Liu B, Wang Q, Jiao R, Xu Y, Wang L, Sun S, Sun X, Younus M, Wang C, Hokfelt T, Zhang B, Gu H, Xu ZD, Zhou Z., 2022
- Differential co-release of two neurotransmitters from a vesicle fusion pore in mammalian adrenal chromaffin cells., Quanfeng Zhang, Bin Liu, Qihui Wu, Bing Liu, Yinglin Li, Suhua Sun, Yuan Wang, Xi Wu, Zuying Chai, Xiaohan Jiang, Xiaoyao Liu, Meiqin Hu, Yeshi Wang, Yunting Yang, Li Wang, Xinjiang Kang, Yingfei Xiong, Yang Zhou, Xiaoke Chen, Lianghong Zheng, Bo Zhang, Changhe Wang, Feipeng Zhu, Zhuan Zhou., 2019
- Regulating quantal size of neurotransmitter release through a GPCR voltage sensor., Quanfeng Zhang, Bing Liu, Yinglin Li, Lili Yin, Muhammad Younus, Xiaohan Jiang, Zhaohan Lin, Xiaoxuan Sun, Rong Huang, Bin Liu, Qihui Wu, Feipeng Zhu, Zhuan Zhou., 2020
- Impaired D2 receptor-dependent dopaminergic transmission in prefrontal cortex of awake mouse model of Parkinson's disease., Mingli Li, Huadong Xu, Guoqing Chen, Suhua Sun, Qinglong Wang, Bing Liu, Xi Wu, Li Zhou, Zuying Chai, Xiaoxuan Sun, Yang Lu, Muhammad Younus, Lianghong Zheng, Feipeng Zhu, Hongbo Jia, Xiaowei Chen, Changhe Wang, Zhuan Zhou., 2019
- Ca2+-independent but voltage-dependent quantal catecholamine secretion (CiVDS) in the mammalian sympathetic nervous system., Rong Huang, Yuan Wang, Jie Li, Xiaohan Jiang, Yinglin Li, Bing Liu, Xi Wu, Xingyu Du, Yuqi Hang, Mu Jin, Feipeng Zhu, Changhe Wang, Zuying Chai, Zhuan Zhou., 2019
- Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology., Changhe Wang, Xinjiang Kang, Li Zhou, Zuying Chai, Qihui Wu, Rong Huang, Huadong Xu, Meiqin Hu, Xiaoxuan Sun, Suhua Sun, Jie Li, Ruiying Jiao, Panli Zuo, Lianghong Zheng, Zhenyu Yue, Zhuan Zhou., 2018
- CaV2.2 Gates Calcium-Independent but Voltage-Dependent Secretion in Mammalian Sensory Neurons., Zuying Chai, Changhe Wang, Rong Huang, Yuan Wang, Xiaoyu Zhang, Qihui Wu, Yeshi Wang, Xi Wu, Lianghong Zheng, Chen Zhang, Wei Guo, Wei Xiong, Jiuping Ding, Feipeng Zhu, Zhuan Zhou., 2017
- Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine., Li Wang, Shujiang Shang, Xinjiang Kang, Sasa Teng, Feipeng Zhu, Bin Liu, Qihui Wu, Mingli Li, Wei Liu, Huadong Xu, Li Zhou, Ruiying Jiao, Haiqiang Dou, Panli Zuo, Xiaoyu Zhang, Lianghong Zheng, Shirong Wang, Changhe Wang, Zhuan Zhou., 2014
- Activation of GPCRs modulates quantal size in chromaffin cells through G(betagamma) and PKC., Xiao-Ke Chen, Lie-Cheng Wang, Yang Zhou, Qian Cai, Murali Prakriya, Kai-Lai Duan, Zu-Hang Sheng, Christopher Lingle, Zhuan Zhou., 2005
- Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons., Zhang C & Zhou Z., 2002
- Calcium- and dynamin-independent endocytosis in dorsal root ganglion neurons., Chen Zhang, Wei Xiong, Hui Zheng, Liecheng Wang, Bai Lu, Zhuan Zhou., 2004
- Reversing a model of Parkinson’s disease with in situ converted nigral neurons., Hao Qian, Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng, Xuan Zhang, Yuanchao Xue, Roy Maimon, Steven F. Dowdy, Neal K. Devaraj, Zhuan Zhou, William C. Mobley, Don W. Cleveland & Xiang-Dong Fu., 2020
Awards
- National Outstanding Youth Fund: Detail
- CAS 'Hundred Talents Program': Detail
- National Excellent Doctoral Dissertation Supervisor: Detail
- American 'Li Foundation Award': Detail
- First Prize of the Ministry of Education's 'Outstanding Scientific Research Achievement Award in Natural Science': Detail
