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Hu Zeng
Life Sciences / Medical / Biology
Peking University
Beijing
Language: Chinese, English
Spatial Sequencing
Single-Cell
Multi-Omics
Neurodegenerative Diseases
Tumors
Molecular Mechanisms
Gene Expression
Transcriptomics
Proteomics
Genomics
Areas of Focus
- Development of novel spatial single-cell multi-omics sequencing technologies
- Investigation of pathogenic mechanisms of major diseases such as neurodegenerative diseases and tumors at the molecular level
Work Experience
- 2020 - 2023 - Broad Institute of MIT and Harvard - Postdoctoral Researcher
- 2023 – Present - Peking University, School of Future Technology - Researcher, Doctoral Supervisor
Academic Background & Achievements
- 2009 – 2013 Bachelor's Degree: Sun Yat-sen University, School of Life Sciences
- 2013 – 2019 Doctorate: Peking University, School of Life Sciences
- Published in Science, Nature Neuroscience, Nature Methods
- Applied for 4 international patents
Publications
- Spatially Resolved single-cell translatomics at molecular resolution, H Zeng, J Huang, J Ren, C K Wang, Z Tang, H Zhou, Y Zhou, H Shi, A Aditham, X Sui, H Chen, J A Lo, X Wang, 2023
- Spatiotemporally resolved transcriptomics reveals the subcellular RNA kinetic landscape, J Ren, H Zhou, H Zeng, C K Wang, J Huang, X Qiu, X Sui, Q Li, X Wu, Z Lin, J A Lo, K Maher, Y He, X Tang, J Lam, H Chen, B Li, D E Fisher, J Liu, X Wang, 2023
- Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease, H Zeng, J Huang, H Zhou, W J. Meilandt, B Dejanovic, Y Zhou, C J. Bohlen, S Lee, J Ren, A Liu, Z Tang, H Sheng, J Liu, M Sheng, X Wang, 2023
- Tissue-specific 5-hydroxymethylcytosine landscape of the human genome, B He, C Zhang, X Zhang, Y Fan, H Zeng, J Liu, H Meng, D Bai, J Peng, Q Zhang, W Tao, C Yi, 2021
- DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes, M Liu, J Zhang, C Zhu, X Zhang, W Xiao, Y Yan, L Liu, H Zeng, YQ Gao, C Yi, 2021
- Chemically modified mocRNAs for highly efficient protein expression in mammalian cells, A Aditham, H Shi, J Guo, H Zeng, Y Zhou, S D Wade, J Huang, J Liu, X Wang, 2022
- Unnatural cytosine bases recognized as thymines by DNA polymerases via the formation of the Watson-Crick geometry, H Zeng, M Mondal, R Song, J Zhang, B Xia, M Liu, C Zhu, B He, YQ Gao, C Yi, 2019
- Compilation of modern technologies to map genome-wide cytosine modifications in DNA, H Zeng, B He, C Yi, 2019
- Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution, H Zeng, B He, B Xia, D Bai, X Lu, J Cai, L Chen, A Zhou, C Zhu, H Meng, Y Gao, H Guo, C He, Q Dai, C Yi, 2018
- Liquid biopsies: DNA methylation analyses in circulating cell-free DNA, H Zeng, B He, C Yi, J Peng, 2018
- Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution, C Zhu, Y Gao, H Guo, B Xia, J Song, X Wu, H Zeng, K Kee, F Tang, C Yi, 2017
- Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale, B Xia, D Han, X Lu, Z Sun, A Zhou, Q Yin, H Zeng, M Liu, X Jiang, W Xie, C He, C Yi, 2015
