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Zusen Fan
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Innate Immunity
Infection
Tumor
Non-Coding Rna
Immune Regulation
Tumor Stem Cells
Tumor Immunity
Subsets
Mechanisms
Discovery
Areas of Focus
- Discovery of new subsets in innate immunity and mechanisms against infection/tumor
- Non-coding RNA and immune regulation
- Tumor stem cells and tumor immunity
Work Experience
- 2003 - 2004 - Harvard Medical School - Lecturer
- 2004 - Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
Academic Background & Achievements
- 1998 - PhD in Immunology: Shanghai Jiao Tong University School of Medicine
- 2003 - Lecturer: Harvard Medical School
- 2004 - Researcher: Institute of Biophysics, Chinese Academy of Sciences
- 2005 - Recipient: Distinguished Young Scholar Fund
- 2006 - Selected: National New Century Talent Project
- 2010 - Expert: State Council Special Allowance
- 2014 - Recipient: Tan Jiazhen Life Science Innovation Award
- 2016, 2018 - Excellent Graduate Advisor: Chinese Academy of Sciences
- 2018 - Recipient: Beijing Science and Technology Progress Award (First Prize)
- 2019 - Chief Scientist: National Natural Science Foundation Innovation Group
- 2020 - Chief Scientist: National Key R&D Program
Publications
- Noncoding RNA circBtnl1 suppresses self-renewal of intestinal stem cells via disruption of Atf4 mRNA stability, Guo, Hui, Zhang, Jiahang, Jiang, Zhimin, Zhu, Xiaoxiao, Yang, Jing, Mu, Rui, Du, Ying, Tian, Yong, Zhu, Pingping, Fan, Zusen, 2023
- FOXO1 orchestrates the intestinal homeostasis via neuronal signaling in group 3 innate lymphoid cells, Shao, Fei, Liu, Zhen, Wei, Qinglin, Yu, Dou, Zhao, Min, Zhang, Xusheng, Gao, Xintong, Fan, Zusen, Wang, Shuo, 2023
- Noncoding RNAs in tumorigenesis and tumor therapy, Pingping Zhu, Benyu Liu, Zusen Fan, 2023
- Regulation of noncoding RNAs in innate lymphoid cells, Liu, Benyu, Zhang, Lingwei, Zhu, Pingping, Fan, Zusen, 2023
- 5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal, pingping zhu, 范祖森, 2022
- Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine, Xiong, Zhen, Zhu, Xiaoxiao, Geng, Jingjing, Xu, Yuwei, Wu, Runyuan, Li, Cunzhen, Fan, Dongdong, Qin, Xiwen, Du, Ying, Tian, Yong, Fan, Zusen, 2022
- circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription, 范祖森, Nian Liu, 2022
- Induction of functional neutrophils from mouse fibroblasts by thymidine through enhancement of Tet3 activity, Ye, Buqing, Yang, Liuliu, Liu, Benyu, Liu, Nian, Fan, Dongdong, Li, Huimu, Sun, Lei, Du, Ying, Wang, Shuo, Tian, Yong, Fan, Zusen, 2022
- Gut microbiota drives macrophage-dependent self-renewal of intestinal stem cells via niche enteric serotonergic neurons, Zhu, Pingping, Lu, Tiankun, Wu, Jiayi, Fan, Dongdong, Liu, Benyu, Zhu, Xiaoxiao, Guo, Hui, Du, Ying, Liu, Feng, Tian, Yong, Fan, Zusen, 2022
- Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF, Chen, Zhenzhen, Lu, Tiankun, Huang, Lan, Wang, Zhiwei, Yan, Zhongyi, Guan, Yubo, Hu, Wenjing, Fan, Zusen, Zhu, Pingping, 2021
- Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m(6)A demethylation of Nr4a1 mRNA, Benyu Liu, Nian Liu, Xiaoxiao Zhu, Liuliu Yang, Buqing Ye, Huimu Li, Pingping Zhu, Tiankun Lu, Yong Tian, Zusen Fan, 2021
- N1-methyladenosinemethylation 1 in tRNA drives liver tumourigenesis by regulating cholesterol metabolism, 范祖森, 2021
- Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling, Gu, Yang, Wang, Yanying, He, Luyun, Zhang, Jiahang, Zhu, Xiaoxiao, Liu, Nian, Wang, Jianyi, Lu, Tiankun, He, Lei, Tian, Yong, Fan, Zusen, 2021
- Induction of functional neutrophils from mouse fibroblasts by thymidine through enhancement of Tet3 activity, Ye, Buqing, Yang, Liuliu, Liu, Benyu, Liu, Nian, Fan, Dongdong, Li, Huimu, Sun, Lei, Du, Ying, Wang, Shuo, Tian, Yong, Fan, Zusen, 2022
Awards
- 2009: Beijing Natural Science Award (Third Prize)
- 2014: Tan Jiazhen Life Science Innovation Award
- 2018: Beijing Science and Technology Progress Award (First Prize)
