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Wenfeng Qian
wfqian@genetics.ac.cn
English, Chinese
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2006-09--2012-08 PhD: University of Michigan
  • 2002-09--2006-07 Bachelor's: Peking University
  • 2012-12 - Present - Institute of Genetics and Developmental Biology, Researcher
  • Walter Fitch Award Finalist (2012): International Society for Molecular Evolution
  • National Self-Funded Scholarship (2012): Special Award
  • Yihai Kerry Excellent Mentor Award (2018)
  • Excellent Young Scientist Fund (2019)
Translational Regulation
Cell Lineage Tracing
Directed Protein Evolution
  • Synonymous somatic mutations that alter proximal out-of-frame downstream ATGs are associated with aberrant gene expression levels in cancer cells, Kong, Jinhui, Zhang, Shuo, Qian, Wenfeng, Li, Ke, 2023
  • A high-resolution transcriptomic atlas depicting nitrogen fixation and nodule development in soybean, Sun, Baocheng, Wang, Yu, Yang, Qun, Gao, Han, Niu, Haiyu, Li, Yansong, Ma, Qun, Huan, Qing, Qian, Wenfeng, Ren, Bo, 2023
  • Distance-dependent inhibition of translation initiation by downstream out-of-frame AUGs is consistent with a Brownian ratchet process of ribosome scanning, Li, Ke, Kong, Jinhui, Zhang, Shuo, Zhao, Tong, Qian, Wenfeng, 2022
  • Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding, Zhao, Taolan, Chen, YanMing, Li, Yu, Wang, Jia, Chen, Siyu, Gao, Ning, Qian, Wenfeng, 2021
  • Host-specific asymmetric accumulation of mutation types reveals that the origin of SARS-CoV-2 is consistent with a natural process, KeJia Shan, Changshuo Wei, Yu Wang, Qing Huan, Wenfeng Qian, 2021
  • Single-cell transcriptome atlas of the leaf and root of rice seedlings, Wang, Yu, Huan, Qing, Li, Ke, Qian, Wenfeng, 2021
  • The memory of neuronal mitochondrial stress is inherited transgenerationally via elevated mitochondrial DNA levels, Zhang, Qian, Wang, Zihao, Zhang, Wenfeng, Wen, Qingbo, Li, Xinyu, Zhou, Jun, Wu, Xueying, Guo, Yongqing, Liu, Yangli, Wei, Changshuo, Qian, Wenfeng, Tian, Ye, 2021
  • The Missing Expression Level-Evolutionary Rate Anticorrelation in Viruses Does Not Support Protein Function as a Main Constraint on Sequence Evolution, Wei, Changshuo, Chen, YanMing, Chen, Ying, Qian, Wenfeng, 2021
  • Codon usage bias and nuclear mRNA concentration: Correlation vs. causation, Wenfeng Qian, Jianzhi Zhang, 2021
  • 翻译延伸的顺式调控机理与生物学效应, 肇涛澜, 张硕, 钱文峰, 2020
  • Impact of poly(A)-tail G-content on Arabidopsis PAB binding and their role in enhancing translational efficiency, Zhao, Taolan, Huan, Qing, Sun, Jing, Liu, Chunyan, Hou, Xiuli, Yu, Xiang, Silverman, Ian M, Zhang, Yi, Gregory, Brian D, Liu, ChunMing, Qian, Wenfeng, Cao, Xiaofeng, 2019
  • The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis, Zhou, Junxiang, Wang, Xin, Wang, Min, Chang, Yuwei, Zhang, Fengxia, Ban, Zhaonan, Tang, Ruofeng, Gan, Qiwen, Wu, Shaohuan, Guo, Ye, Zhang, Qian, Wang, Fengyang, Zhao, Liyuan, Jing, Yudong, Qian, Wenfeng, Wang, Guodong, Guo, Weixiang, Yang, Chonglin, 2019
  • Overdosage of Balanced Protein Complexes Reduces Proliferation Rate in Aneuploid Cells, Chen, Ying, Chen, Siyu, Li, Ke, Zhang, Yuliang, Huang, Xiahe, Li, Ting, Wu, Shaohuan, Wang, Yingchun, Carey, Lucas B, Qian, Wenfeng, 2019
  • Synchronized replication of genes encoding the same protein complex in fast-proliferating cells, Chen, Ying, Li, Ke, Chu, Xiao, Carey, Lucas B, Qian, Wenfeng, 2019
  • HeteroMeth: A Database of Cell-to-cell Heterogeneity in DNA Methylation, Huan, Qing, Zhang, Yuliang, Wu, Shaohuan, Qian, Wenfeng, 2018
  • Reduced intrinsic DNA curvature leads to increased mutation rate, Duan, Chaorui, Huan, Qing, Chen, Xiaoshu, Wu, Shaohuan, Carey, Lucas B, He, Xionglei, Qian, Wenfeng, 2018
  • Codon-Resolution Analysis Reveals a Direct and Context-Dependent Impact of Individual Synonymous Mutations on mRNA Level, Chen, Siyu, Li, Ke, Cao, Wenqing, Wang, Jia, Zhao, Tong, Huan, Qing, Yang, YuFei, Wu, Shaohuan, Qian, Wenfeng, 2017
  • Genetic Interaction Network as an Important Determinant of Gene Order in Genome Evolution, Yang, YuFei, Cao, Wenqing, Wu, Shaohuan, Qian, Wenfeng, 2017
  • Independent regulation of gene expression level and noise by histone modifications, Wu, Shaohuan, Li, Ke, Li, Yingshu, Zhao, Tong, Li, Ting, Yang, YuFei, Qian, Wenfeng, 2017
  • Single-cell transcriptome analysis reveals widespread monoallelic gene expression in individual rice mesophyll cells, Han, YingYing, Chu, Xiao, Yu, HaoPeng, Ma, YingKe, Wang, XiuJie, Qian, WenFeng, Jiao, YuLing, 2017
  • Trans-splicing enhances translational efficiency in C. elegans, Yang, YuFei, Zhang, Xiaoqing, Ma, Xuehua, Zhao, Taolan, Sun, Qiushi, Huan, Qing, Wu, Shaohuan, Du, Zhuo, Qian, Wenfeng, 2017
  • A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice (Oryza sativa L.), Zhang, Biyao, Wu, Shaohuan, Zhang, Yue, Xu, Ting, Guo, Feifei, Tang, Huashan, Li, Xiang, Wang, Pengfei, Qian, Wenfeng, Xue, Yongbiao, 2016
  • The fitness landscape of a tRNA gene, Li, Chuan, Qian, Wenfeng, Maclean, Calum J, Zhang, Jianzhi, 2016
  • Genomic evidence for adaptation by gene duplication, Qian, Wenfeng, Zhang, Jianzhi, 2014
  • Genomic evidence for elevated mutation rates in highly expressed genes, Park, Chungoo, Qian, Wenfeng, Zhang, Jianzhi, 2012
  • Measuring the evolutionary rate of protein-protein interaction, Qian, Wenfeng, He, Xionglei, Chan, Edwin, Xu, Huailiang, Zhang, Jianzhi, 2011
  • Maintenance of duplicate genes and their functional redundancy by reduced expression, Qian, Wenfeng, Liao, BenYang, Chang, Andrew YingFei, Zhang, Jianzhi, 2010
  • Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks, He, Xionglei, Qian, Wenfeng, Wang, Zhi, Li, Ying, Zhang, Jianzhi, 2010
  • Protein Subcellular Relocalization in the Evolution of Yeast Singleton and Duplicate Genes, Qian, Wenfeng, Zhang, Jianzhi, 2009
  • Positive selection for elevated gene expression noise in yeast, Zhang, Zhihua, Qian, Wenfeng, Zhang, Jianzhi, 2009
  • Evolutionary dynamics of nematode operons: Easy come, slow go, Qian, Wenfeng, Zhang, Jianzhi, 2008
  • Gene dosage and gene duplicability, Qian, Wenfeng, Zhang, Jianzhi, 2008
Gene Expression Ribosome Mrna Protein Synthesis Genetic Code Mutation Evolution Cell Differentiation Protein Engineering Biotechnology

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