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Ping Zhu
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Cryo-Em
Electron Tomography
Biomolecular Structure
Function Research
In Situ Structure Analysis
Visualization
Chromatin
Epigenetics
Virus
Replication
Areas of Focus
- Cryo-Electron Microscopy
- Chromatin Structure and Epigenetic Regulation
- Virus Infection and Replication Mechanisms
Work Experience
- 2008-06~Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
- 1999-03~2008-05 - Florida State University, USA - Postdoctoral, Assistant Researcher, Associate Researcher
- 1997-07~1998-12 - Tsinghua University - Lecturer
Academic Background & Achievements
- 1993-09--1997-07 PhD: Tsinghua University
- 1990-09--1993-07 Master's: Xi'an Jiaotong University
- 1986-09--1990-07 Bachelor's: Zhejiang University
- 2014: National 'Outstanding Youth Science Fund' recipient
Publications
- Decoding silkworm spinning programmed by pH and metal ions, Ping Zhu, 2024
- Structure of the transcription open complex of distinct σI factors., Ping Zhu, 2023
- Cryo-ET study from invitro to invivo revealed a general folding mode of chromatin with two-start helical architecture, Ping Zhu, 2023
- A method for restoring signals and revealing individual macromolecule states in cryo-ET, REST, Ping Zhu, 2023
- A strategy combining denoising and cryo-EM single particle analysis, Ping Zhu, 2023
- Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1, Ping Zhu, 2023
- 不同金属离子对人胰岛淀粉样多肽纤维形成的影响研究, Ping Zhu, 2022
- Noise-Transfer2Clean: denoising cryo-EM images based on noise modeling and transfer, Ping Zhu, 2022
- A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core, Ping Zhu, 2022
- In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation, Ping Zhu, 2022
- Cryo-EM structures of infectious bursal disease virus with different virulence provide insights on their assembly and invasion, Ping Zhu, 2022
- Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor, Ping Zhu, 2022
- Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2, Ping Zhu, 2021
- Cryo‐electron microscopy structure of CLHM1 ion channel from Caenorhabditis elegans, Ping Zhu, 2020
- Structural characterization and cryo-electron tomography analysis of human islet amyloid polypeptide suggest a synchronous process of the hIAPP1−37 amyloid fibrillation, Ping Zhu, 2020
- Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures, Ping Zhu, 2020
- Cryo-electron microscopy structure of the SADS-CoV spike glycoprotein provides insights into an evolution of unique coronavirus spike proteins, Ping Zhu, 2020
- Cryo-EM structure of native spherical subviral particles isolated from HBV carriers, Ping Zhu, 2019
- Novel Sulfolobus Virus with an Exceptional Capsid Architecture, Ping Zhu, 2018
- Higher-Order Structure of the 30-nm Chromatin Fiber Revealed by Cryo-EM, Ping Zhu, 2016
- The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism, Ping Zhu, 2016
- Structural insights of nucleosome and the 30-nm chromatin fiber, Ping Zhu, 2016
- Molecular characteristics and evolutionary analysis of a very virulent infectious bursal disease virus, Ping Zhu, 2015
- 冷冻电镜技术在表观遗传学研究中的应用, Ping Zhu, 2015
- Structure and organization of chromatin fiber in the nucleus, Ping Zhu, 2015
- Analysis of Chromatin Fiber in Hela Cell with Electron Tomography, Ping Zhu, 2015
- No longer'blob-ology':Cryo-EM is getting into molecular details, Ping Zhu, 2015
- 人源HDAC1/2-RbAp46/48核心复合物三维空间构象的电子显微分析, Ping Zhu, 2014
- New insights into the helical structure of 30-nm chromatin fibers, Ping Zhu, 2014
- Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units, Ping Zhu, 2014
- Cryo-EM Structure of Isomeric Molluscan Hemocyanin Triggered by Viral Infection, Ping Zhu, 2014
- A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family, Ping Zhu, 2014
- Cryo-EM structures of two bovine adenovirus type 3 intermediates, Ping Zhu, 2014
- Cryo-EM study of insect cell-expressed Enterovirus 71 and Coxsackievirus A16 virus-like particles provides a structural basis for vaccine development, Ping Zhu, 2014
- 30 nm 染色质的体外组装和电镜分析, Ping Zhu, 2013
- Cryo-EM structure of a transcribing cypovirus, Ping Zhu, 2012
- Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping, Ping Zhu, 2011
- 冷冻电子断层成像技术及其在生物研究领域的应用, Ping Zhu, 2010
- Cryoelectron Tomography of HIV-1 Envelope Spikes: Further Evidence for Tripod-Like Legs, Ping Zhu, 2008
- Distribution and three-dimensional structure of AIDS virus envelope spikes, Ping Zhu, 2006
- Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions, Ping Zhu, 2003
- Structural Flexibility and Function Valency of CD4-IgG2 (PRO 542): Potential for Crosslinking HIV-1 Envelope Spikes, Ping Zhu, 2001
Awards
- 2022: Chinese Academy of Sciences Outstanding Scientific Achievement Award
- 2019: Beijing Science and Technology Award, Second Prize
- 2016: State Council Special Government Allowance
- 2015: Chinese Academy of Sciences Excellent Doctoral Dissertation Supervisor Award
- 2014: Chinese Academy of Sciences Excellent Mentor Award
- 2014: National Outstanding Youth Science Fund
- 2014: Chinese Academy of Sciences 'Zhu Li Yuehua Excellent Teacher Award'
