Professor | Wenxiang Cheng | Asia Growth Partners

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Name	Wenxiang Cheng
Contact Information	wx.cheng@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Wenxiang Cheng

Contact Information

wx.cheng@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2016-09--2020-07 PhD: University of Chinese Academy of Sciences 2004-09--2007-07 Master's: Shantou University
Work Experience	2011-01~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2007-07~2011-01 - AstraZeneca China Innovation Center - Assistant Scientist
Awards	3D Printing Personalized Bone Defect Repair Implant Key Technology and Clinical Application (2021): Second Prize, Provincial Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2016-09--2020-07 PhD: University of Chinese Academy of Sciences
2004-09--2007-07 Master's: Shantou University

Work Experience

2011-01~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2007-07~2011-01 - AstraZeneca China Innovation Center - Assistant Scientist

Awards

3D Printing Personalized Bone Defect Repair Implant Key Technology and Clinical Application (2021): Second Prize, Provincial Level

Areas of Focus	Inflammatory Bone Disease Drug Therapy Osteoclast Function Protein Structure
Publications	Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis, Gan, Donghao, Cheng, Wenxiang, Ke, Liqing, Sun, Antonia RuJia, Jia, Qingyun, Chen, Jianhai, Lin, Jietao, Li, Jian, Xu, Zhanwang, Zhang, Peng, 2021 Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor, Chen, Jianhai, Li, Jian, Chen, Jinqing, Cheng, Wenxiang, Lin, Jietao, Ke, Liqing, Liu, Gang, Bai, Xueling, Zhang, Peng, 2021 The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model, Cheng, Wenxiang, Gan, Donghao, Hu, Yiping, Zheng, Zhengtan, Zeng, Qingqiang, Li, Ling, Wang, Xinluan, Zhang, Yong, Xu, Zhanwang, Qin, Ling, Zhang, Peng, 2021 Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats, Cheng, WenXiang, Zhong, Shan, Meng, XiangBo, Zheng, NianYe, Zhang, Peng, Wang, Yun, Qin, Ling, Wang, XinLuan, 2020 Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomised rats, Li, Ling, Yi, Xiaomin, Huang, Cuishan, Shi, Keda, Wang, Jiani, Zeng, Qingqiang, Cheng, Wenxiang, He, Xiangjiu, Zhang, Peng, Qiu, Guixing, Qin, Ling, Wang, Xinluan, 2020 Downregulation of Hypoxia-Inducible Factor-1 alpha by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats, Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Song, Bing, Wang, Qingwen, Qin, Ling, Zhang, Peng, 2020 Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway, Cheng, WenXiang, Huang, Huan, Chen, JianHai, Zhang, TianTian, Zhu, GuoYuan, Zheng, ZhengTan, Lin, JieTao, Hu, YiPing, Zhang, Yong, Bai, XueLing, Wang, Yan, Xu, ZhanWang, Song, Bing, Mao, YiYing, Yang, Fei, Zhang, Peng, 2020 THP-1源巨噬细胞上清液对类风湿性关节炎成纤维细胞和血管内皮细胞的作用, 林结桃, 李健, 成文翔, SUN, Antonia, 陈建海, 柯丽青, 甘东浩, 张鹏, 2020 Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing, Peng, Lihua, Xing, Rui, Liu, Dongbing, Bao, Li, Cheng, Wenxiang, Wang, Hongyi, Yu, Yuan, Liu, Xiaofeng, Jiang, Lu, Wu, Yan, An, Zhongxue, Liang, Qiaoyi, Kim, Ryong Nam, Shin, Young Kee, Yang, Huanming, Wang, Jian, Yu, Jun, Zhang, Xiuqing, Xu, Xun, Yang, Jiaan, Wu, Kui, Zhu, Shida, Lu, Youyong, 2019 Fracture healing in a collagen-induced arthritis rat model: Radiology and histology evidence, Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Xu, Zhanwang, Song, Bing, Mao, YiYing, Yang, Fei, Zhang, Peng, 2018 Relationship between heterotopic ossification and traumatic brain injury Why severe traumatic brain injury increases the risk of heterotopic ossification, Huang, Huan, Cheng, WenXiang, Hu, YiPing, Chen, JianHai, Zheng, ZhengTan, Zhang, Peng, 2018 Biodegradable Magnesium Screws Accelerate Fibrous Tissue Mineralization at the Tendon-Bone Insertion in Anterior Cruciate Ligament Reconstruction Model of Rabbit, Wang, Jiali, Xu, Jiankun, Fu, Weimin, Cheng, Wenxiang, Chan, Kaiming, Yung, Patrick Shuhang, Qin, Ling, 2017 Cucurbitacin E inhibits TNF-alpha-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-kappa B pathways, Jia, Qingyun, Cheng, Wenxiang, Yue, Ye, Hu, Yipping, Zhang, Jian, Pan, Xiaohua, Xu, Zhanwang, Zhang, Peng, 2015 骨折愈合的影响因素概述, 马应亚, 岳野, 虎义平, 成文翔, 汪洁, 王均, 张鹏, 2015 类风湿性关节炎与IL-1/IL-1Ra平衡关系的研究进展, 汪洁, 汪洁, 岳野, 成文翔, 虎义平, 马应亚, 王均, 张鹏, 2015 GTS-21 attenuates lipopolysaccharide-induced inflammatory cytokine production in vitro by modulating the Akt and NF-kappa B signaling pathway through the alpha 7 nicotinic acetylcholine receptor, Yue, Ye, Liu, Ruoxi, Cheng, Wenxiang, Hu, Yiping, Li, Jinchao, Pan, Xiaohua, Zhang, Peng, 2015 Genistein suppresses tumor necrosis factor alpha-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor kappa B and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells, Li, Jinchao, Li, Jun, Yue, Ye, Hu, Yiping, Cheng, Wenxiang, Liu, Ruoxi, Pan, Xiaohua, Zhang, Peng, 2014 Occurrence of low frequency PIK3CA and AKT2 mutations in gastric cancer, Zhang, QingYing, Cheng, WenXiang, Li, WenMei, Au, William, Lu, YouYong, 2014 Attenuation of Collagen-Induced Arthritis in Rat by Nicotinic Alpha7 Receptor Partial Agonist GTS-21, Hu, Yiping, Liu, Ruoxi, Li, Jinchao, Yue, Ye, Cheng, Wenxiang, Zhang, Peng, 2014 Advances in research on animal models of rheumatoid arthritis, Hu, Yiping, Cheng, Wenxiang, Cai, Wenhong, Yue, Ye, Li, Jinchao, Zhang, Peng, 2013 Genistein: the potential for efficacy in rheumatoid arthritis, Li, Jinchao, Gang, Dong, Yu, Xiaowei, Hu, Yiping, Yue, Ye, Cheng, Wenxiang, Pan, Xiaohua, Zhang, Peng, 2013 Puerarin promotes osteogenesis and inhibits adipogenesis in vitro, Wang, Nan, Wang, Xinluan, Cheng, Wenxiang, Cao, Huijuan, Zhang, Peng, Qin, Ling, 2013 Effects of tetracyclines on bones: an ambiguous question needs to be clarified, Cheng, Wenxiang, Yue, Ye, Fan, Wenbin, Hu, Yiping, Wang, Xinluan, Pan, Xiaohua, Zhou, Xiaoxiao, Qin, Ling, Zhang, Peng, 2012 尕代类风湿关节炎成纤维样滑膜细胞及成熟细胞系生长特性的比较, 蔡文虹, 孙保东, 张宝凤, 岳野, 成文翔, 李金超, 虎义平, 张鹏, 2012 类风湿性关节炎病因学概述, 蔡文虹, 孙保东, 张宝凤, 岳野, 成文翔, 虎义平, 张鹏, 2012 两种方法分离培养类风湿性关节炎成纤维样滑膜细胞的比较, 蔡文虹, 孙保东, 张宝凤, 成文翔, 岳野, 虎义平, 李金超, 张鹏, 2012 中医在类风湿性关节炎治疗中的应用, 蔡文虹, 孙保东, 张宝凤, 成文翔, 虎义平, 岳野, 张鹏, 2012 类风湿性关节炎动物模型研究进展, 蔡文虹, 孙保东, 张宝凤, 虎义平, 成文翔, 岳野, 张鹏, 2012 FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-beta-CyD, Hu, Yiping, Tang, Guping, Liu, Jun, Cheng, Wenxiang, Yue, Ye, Li, Jinchao, Zhang, Peng, 2012

Areas of Focus

Inflammatory Bone Disease
Drug Therapy
Osteoclast Function
Protein Structure

Publications

Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis, Gan, Donghao, Cheng, Wenxiang, Ke, Liqing, Sun, Antonia RuJia, Jia, Qingyun, Chen, Jianhai, Lin, Jietao, Li, Jian, Xu, Zhanwang, Zhang, Peng, 2021
Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor, Chen, Jianhai, Li, Jian, Chen, Jinqing, Cheng, Wenxiang, Lin, Jietao, Ke, Liqing, Liu, Gang, Bai, Xueling, Zhang, Peng, 2021
The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model, Cheng, Wenxiang, Gan, Donghao, Hu, Yiping, Zheng, Zhengtan, Zeng, Qingqiang, Li, Ling, Wang, Xinluan, Zhang, Yong, Xu, Zhanwang, Qin, Ling, Zhang, Peng, 2021
Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats, Cheng, WenXiang, Zhong, Shan, Meng, XiangBo, Zheng, NianYe, Zhang, Peng, Wang, Yun, Qin, Ling, Wang, XinLuan, 2020
Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomised rats, Li, Ling, Yi, Xiaomin, Huang, Cuishan, Shi, Keda, Wang, Jiani, Zeng, Qingqiang, Cheng, Wenxiang, He, Xiangjiu, Zhang, Peng, Qiu, Guixing, Qin, Ling, Wang, Xinluan, 2020
Downregulation of Hypoxia-Inducible Factor-1 alpha by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats, Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Song, Bing, Wang, Qingwen, Qin, Ling, Zhang, Peng, 2020
Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway, Cheng, WenXiang, Huang, Huan, Chen, JianHai, Zhang, TianTian, Zhu, GuoYuan, Zheng, ZhengTan, Lin, JieTao, Hu, YiPing, Zhang, Yong, Bai, XueLing, Wang, Yan, Xu, ZhanWang, Song, Bing, Mao, YiYing, Yang, Fei, Zhang, Peng, 2020
THP-1源巨噬细胞上清液对类风湿性关节炎成纤维细胞和血管内皮细胞的作用, 林结桃, 李健, 成文翔, SUN, Antonia, 陈建海, 柯丽青, 甘东浩, 张鹏, 2020
Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing, Peng, Lihua, Xing, Rui, Liu, Dongbing, Bao, Li, Cheng, Wenxiang, Wang, Hongyi, Yu, Yuan, Liu, Xiaofeng, Jiang, Lu, Wu, Yan, An, Zhongxue, Liang, Qiaoyi, Kim, Ryong Nam, Shin, Young Kee, Yang, Huanming, Wang, Jian, Yu, Jun, Zhang, Xiuqing, Xu, Xun, Yang, Jiaan, Wu, Kui, Zhu, Shida, Lu, Youyong, 2019
Fracture healing in a collagen-induced arthritis rat model: Radiology and histology evidence, Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Xu, Zhanwang, Song, Bing, Mao, YiYing, Yang, Fei, Zhang, Peng, 2018
Relationship between heterotopic ossification and traumatic brain injury Why severe traumatic brain injury increases the risk of heterotopic ossification, Huang, Huan, Cheng, WenXiang, Hu, YiPing, Chen, JianHai, Zheng, ZhengTan, Zhang, Peng, 2018
Biodegradable Magnesium Screws Accelerate Fibrous Tissue Mineralization at the Tendon-Bone Insertion in Anterior Cruciate Ligament Reconstruction Model of Rabbit, Wang, Jiali, Xu, Jiankun, Fu, Weimin, Cheng, Wenxiang, Chan, Kaiming, Yung, Patrick Shuhang, Qin, Ling, 2017
Cucurbitacin E inhibits TNF-alpha-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-kappa B pathways, Jia, Qingyun, Cheng, Wenxiang, Yue, Ye, Hu, Yipping, Zhang, Jian, Pan, Xiaohua, Xu, Zhanwang, Zhang, Peng, 2015
骨折愈合的影响因素概述, 马应亚, 岳野, 虎义平, 成文翔, 汪洁, 王均, 张鹏, 2015
类风湿性关节炎与IL-1/IL-1Ra平衡关系的研究进展, 汪洁, 汪洁, 岳野, 成文翔, 虎义平, 马应亚, 王均, 张鹏, 2015
GTS-21 attenuates lipopolysaccharide-induced inflammatory cytokine production in vitro by modulating the Akt and NF-kappa B signaling pathway through the alpha 7 nicotinic acetylcholine receptor, Yue, Ye, Liu, Ruoxi, Cheng, Wenxiang, Hu, Yiping, Li, Jinchao, Pan, Xiaohua, Zhang, Peng, 2015
Genistein suppresses tumor necrosis factor alpha-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor kappa B and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells, Li, Jinchao, Li, Jun, Yue, Ye, Hu, Yiping, Cheng, Wenxiang, Liu, Ruoxi, Pan, Xiaohua, Zhang, Peng, 2014
Occurrence of low frequency PIK3CA and AKT2 mutations in gastric cancer, Zhang, QingYing, Cheng, WenXiang, Li, WenMei, Au, William, Lu, YouYong, 2014
Attenuation of Collagen-Induced Arthritis in Rat by Nicotinic Alpha7 Receptor Partial Agonist GTS-21, Hu, Yiping, Liu, Ruoxi, Li, Jinchao, Yue, Ye, Cheng, Wenxiang, Zhang, Peng, 2014
Advances in research on animal models of rheumatoid arthritis, Hu, Yiping, Cheng, Wenxiang, Cai, Wenhong, Yue, Ye, Li, Jinchao, Zhang, Peng, 2013
Genistein: the potential for efficacy in rheumatoid arthritis, Li, Jinchao, Gang, Dong, Yu, Xiaowei, Hu, Yiping, Yue, Ye, Cheng, Wenxiang, Pan, Xiaohua, Zhang, Peng, 2013
Puerarin promotes osteogenesis and inhibits adipogenesis in vitro, Wang, Nan, Wang, Xinluan, Cheng, Wenxiang, Cao, Huijuan, Zhang, Peng, Qin, Ling, 2013
Effects of tetracyclines on bones: an ambiguous question needs to be clarified, Cheng, Wenxiang, Yue, Ye, Fan, Wenbin, Hu, Yiping, Wang, Xinluan, Pan, Xiaohua, Zhou, Xiaoxiao, Qin, Ling, Zhang, Peng, 2012
尕代类风湿关节炎成纤维样滑膜细胞及成熟细胞系生长特性的比较, 蔡文虹, 孙保东, 张宝凤, 岳野, 成文翔, 李金超, 虎义平, 张鹏, 2012
类风湿性关节炎病因学概述, 蔡文虹, 孙保东, 张宝凤, 岳野, 成文翔, 虎义平, 张鹏, 2012
两种方法分离培养类风湿性关节炎成纤维样滑膜细胞的比较, 蔡文虹, 孙保东, 张宝凤, 成文翔, 岳野, 虎义平, 李金超, 张鹏, 2012
中医在类风湿性关节炎治疗中的应用, 蔡文虹, 孙保东, 张宝凤, 成文翔, 虎义平, 岳野, 张鹏, 2012
类风湿性关节炎动物模型研究进展, 蔡文虹, 孙保东, 张宝凤, 虎义平, 成文翔, 岳野, 张鹏, 2012
FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-beta-CyD, Hu, Yiping, Tang, Guping, Liu, Jun, Cheng, Wenxiang, Yue, Ye, Li, Jinchao, Zhang, Peng, 2012

Inflammation Bone Disease Therapy Drug Osteoclast Function Protein Structure Mechanism

Min Guan - University of Chinese Academy of Sciences

Zhenyu Yao - University of Chinese Academy of Sciences

Jie Qian - Tongji University

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