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Min Guan
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Bone
Joint
Metabolism
Disease
Drug
Development
Regulation
Stem Cells
Regeneration
Nuclear Receptors
Areas of Focus
- Bone and Joint Diseases
- Metabolic Diseases
- Drug Development
- Metabolic Regulation
- Stem Cells and Tissue Regeneration
- Nuclear Receptors and Transcriptional Regulation
Work Experience
- 2018-01 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher (PI)
- 2013-01 to 2017-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher (PI)
- 2011-12 to 2012-12 - Johns Hopkins University School of Medicine - Postdoctoral Researcher
- 2009-11 to 2011-11 - University of California, Davis School of Medicine - Postdoctoral Researcher
Academic Background & Achievements
- 2006-09 to 2009-07 PhD: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
- 2001-09 to 2004-07 Master's: Jinan University
- 1997-09 to 2001-07 Bachelor's: South China Normal University
Publications
- Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow, Corresponding Author, 2024
- Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca 2+ /CaMKII and PKA Pathways and Multiple-Enzyme Inhibition, 5th Author, 2023
- Nicotine rebalances NAD(+) homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity, 7th Author, 2023
- Andrographolide Inhibits Intestinal Lipid Secretion via Antagonizing Estrogen-Related ReceptorαActivity, Corresponding Author, 2023
- Oligostilbenes from the seeds of Paeonia lactiflora as potent GLP-1 secretagogues targeting TGR5 receptor, 5th Author, 2022
- A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions, 7th Author, 2022
- Highly Purified Eicosapentaenoic Acid Alleviates the Inflammatory Response and Oxidative Stress in Macrophages during Atherosclerosis via the miR-1a-3p/sFRP1/Wnt/PCP-JNK Pathway, 8th Author, 2022
- Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially, 9th Author, 2021
- Strontium regulates stem cell fate during osteogenic differentiation through asymmetric cell division, 5th Author, 2021
- ZnL 2-BPs Integrated Bone Scaffold under Sequential Photothermal Mediation: A Win-Win Strategy Delivering Antibacterial Therapy and Fostering Osteogenesis Thereafter, 6th Author, 2021
- An ERRα antagonist Compound 29 protects against obesity-induced osteoclastic bone loss, Corresponding Author, 2021
- Communication:The Role of Metabolic Regulation and Differentiation in Bone Cells, Corresponding Author, 2021
- Andrographolide prevents bone loss via targeting estrogen-related receptor-alpha-regulated metabolic adaption of osteoclastogenesis, Corresponding Author, 2021
- Lipid Disorders in NAFLD and Chronic Kidney Disease, Corresponding Author, 2021
- Role of Steroid Hormones in the Pathogenesis of Nonalcoholic Fatty Liver Disease, Corresponding Author, 2021
- Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development, Corresponding Author, 2020
- Aptasensor-enabled quantitative analysis of nanosized extracellular vesicles by flow cytometry, 7th Author, 2020
- Circulating MicroRNA-19b Identified From Osteoporotic Vertebral Compression Fracture Patients Increases Bone Formation, Corresponding Author, 2020
- Andrographolide modulates HNF4 alpha activity imparting on hepatic metabolism, Corresponding Author, 2020
- 18 beta-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism, Corresponding Author, 2020
- Zinc Homeostasis in Bone: Zinc Transporters and Bone Diseases, Corresponding Author, 2020
- Tuning the surface immunomodulatory functions of polyetheretherketone for enhanced osseointegration, 8th Author, 2020
- Near-infrared light control of bone regeneration with biodegradable photothermal osteoimplant, 9th Author, 2019
- Estrogen-related receptor gamma regulates hepatic triglyceride metabolism through phospholipase A2 G12B, 5th Author, 2019
- Runx2/Osterix and Zinc Uptake Synergize to Orchestrate Osteogenic Differentiation and Citrate Containing Bone Apatite Formation., Corresponding Author, 2018
- Scavenger receptor-mediated Ad5 entry and acLDL accumulation in monocytes/macrophages synergistically trigger innate responses against viral infection, 6th Author, 2018
- Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells., Corresponding Author, 2017
- Lactose-Functionalized Gold Nanorods for Sensitive and Rapid Serological Diagnosis of Cancer, 6th Author, 2016
- Activation of farnesoid X receptor promotes triglycerides lowering by suppressing phospholipase A2 G12B expression, Corresponding Author, 2016
- Bone turnover and articular cartilage differences localized to subchondral cysts in knees with advanced osteoarthritis, Not mentioned, 2015
- Elevated Mean Arterial Pressure Is Associated With Higher Rate of Subchondral Bone Turnover in Patients With Knee Osteoarthritis., 2nd Author, 2014
- Reversing Bone Loss by Directing Mesenchymal Stem Cells to Bone, 2nd Author, 2013
- Wntless functions in mature osteoblasts to regulate bone mass, 8th Author, 2012
- Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass, 1st Author, 2012
- Glucocorticoid dose determines osteocyte cell fate, 3rd Author, 2011
- Hepatocyte nuclear factor-4 alpha regulates liver triglyceride metabolism in part through secreted phospholipase A2 GXIIB, 1st Author, 2011
- Inhibition of the Progesterone Nuclear Receptor during the Bone Linear Growth Phase Increases Peak Bone Mass in Female Mice, 7th Author, 2010
Awards
- Guangdong Province High-Level Talent Special Support Program for Young Top Talents in Technological Innovation (2018): Special Prize
- Member of the Youth Promotion Association of the Chinese Academy of Sciences (2015)
- Funding for Science and Technology Activities of Returned Overseas Students (2015): Ministry Level
- Shenzhen Overseas High-Level Peacock Program Category B Talent (2014): Second Prize
- Outstanding Postdoctoral Award, University of California, Davis School of Medicine (2011): Special Prize
- ASBMR-Lilly/Pfizer Young Investigator Award, American Society for Bone and Mineral Research (2011): Special Prize
- Alice L. Jee Memorial Young Investigator Award, International Bone Mineral Society (2011): Special Prize
