Professor | Wanze Chen | Asia Growth Partners

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Name	Wanze Chen
Contact Information	wz.chen@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Wanze Chen

Contact Information

wz.chen@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2007-09 to 2013-06 PhD: Xiamen University
Work Experience	2021-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher 2015-02 to 2021-06 - École Polytechnique Fédérale de Lausanne, Switzerland - Postdoctoral Researcher 2007-09 to 2013-06 - Xiamen University - PhD

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2007-09 to 2013-06 PhD: Xiamen University

Work Experience

2021-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher
2015-02 to 2021-06 - École Polytechnique Fédérale de Lausanne, Switzerland - Postdoctoral Researcher
2007-09 to 2013-06 - Xiamen University - PhD

Areas of Focus	Cell Fate Determination Stem Cell Biology Single-Cell Omics
Publications	Resolving cellular dynamics using single-cell temporal transcriptomics, 3rd Author, 2024 Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets, 10th Author, 2022 Live-seq enables temporal transcriptomic recording of single cells, 1st Author, 2022 ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer, 1st Author, 2019 Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors During Lactation, 3rd Author, 2018 Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein, 6th Author, 2018 Dissecting the brown adipogenic regulatory network using integrative genomics, 6th Author, 2017 Clnk plays a role in TNF-alpha-induced cell death in murine fibrosarcoma cell line L929, 4th Author, 2015 RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice, 5th Author, 2015 Ppm1b negatively regulates necroptosis through dephosphorylating Rip3, 1st Author, 2015 The Gαi-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation, 2nd Author, 2014 pelo Is Required for High Efficiency Viral Replication, 6th Author, 2014 Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis, 8th Author, 2013 Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling, 1st Author, 2013 Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor-induced apoptosis of MCF-7 cells, Not mentioned, 2007

Areas of Focus

Cell Fate Determination
Stem Cell Biology
Single-Cell Omics

Publications

Resolving cellular dynamics using single-cell temporal transcriptomics, 3rd Author, 2024
Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets, 10th Author, 2022
Live-seq enables temporal transcriptomic recording of single cells, 1st Author, 2022
ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer, 1st Author, 2019
Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors During Lactation, 3rd Author, 2018
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein, 6th Author, 2018
Dissecting the brown adipogenic regulatory network using integrative genomics, 6th Author, 2017
Clnk plays a role in TNF-alpha-induced cell death in murine fibrosarcoma cell line L929, 4th Author, 2015
RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice, 5th Author, 2015
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3, 1st Author, 2015
The Gαi-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation, 2nd Author, 2014
pelo Is Required for High Efficiency Viral Replication, 6th Author, 2014
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis, 8th Author, 2013
Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling, 1st Author, 2013
Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor-induced apoptosis of MCF-7 cells, Not mentioned, 2007

Cell Fate Determination: Cell Differentiation Cell Development Gene Expression Signaling Pathways Stem Cells Cellular Dynamics Molecular Mechanisms Cell Lineage Cell Plasticity Cell Reprogramming Stem Cell Biology: Stem Cell Differentiation Stem Cell Therapy Regenerative Medicine Pluripotency Stem Cell Niches Stem Cell Markers Stem Cell Signaling Stem Cell Culture Stem Cell Transplantation Stem Cell Research Single-Cell Omics: Single-Cell Rna Sequencing Single-Cell Genomics Single-Cell Proteomics Single-Cell Transcriptomics Single-Cell Analysis Single-Cell Technology Single-Cell Data Single-Cell Bioinformatics Single-Cell Applications Single-Cell Research

Huai-Xiao Ma - University of Chinese Academy of Sciences

Xionglei He - Sun Yat-Sen University

University of Chinese Academy of Sciences

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