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Wanze Chen
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Cell Fate Determination: Cell Differentiation
Cell Development
Gene Expression
Signaling Pathways
Stem Cells
Cellular Dynamics
Molecular Mechanisms
Cell Lineage
Cell Plasticity
Cell Reprogramming
Stem Cell Biology: Stem Cell Differentiation
Stem Cell Therapy
Regenerative Medicine
Pluripotency
Stem Cell Niches
Stem Cell Markers
Stem Cell Signaling
Stem Cell Culture
Stem Cell Transplantation
Stem Cell Research
Single-Cell Omics: Single-Cell Rna Sequencing
Single-Cell Genomics
Single-Cell Proteomics
Single-Cell Transcriptomics
Single-Cell Analysis
Single-Cell Technology
Single-Cell Data
Single-Cell Bioinformatics
Single-Cell Applications
Single-Cell Research
Areas of Focus
- Cell Fate Determination
- Stem Cell Biology
- Single-Cell Omics
Work Experience
- 2021-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher
- 2015-02 to 2021-06 - École Polytechnique Fédérale de Lausanne, Switzerland - Postdoctoral Researcher
- 2007-09 to 2013-06 - Xiamen University - PhD
Academic Background & Achievements
- 2007-09 to 2013-06 PhD: Xiamen University
Publications
- Resolving cellular dynamics using single-cell temporal transcriptomics, 3rd Author, 2024
- Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets, 10th Author, 2022
- Live-seq enables temporal transcriptomic recording of single cells, 1st Author, 2022
- ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer, 1st Author, 2019
- Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors During Lactation, 3rd Author, 2018
- Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein, 6th Author, 2018
- Dissecting the brown adipogenic regulatory network using integrative genomics, 6th Author, 2017
- Clnk plays a role in TNF-alpha-induced cell death in murine fibrosarcoma cell line L929, 4th Author, 2015
- RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice, 5th Author, 2015
- Ppm1b negatively regulates necroptosis through dephosphorylating Rip3, 1st Author, 2015
- The Gαi-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation, 2nd Author, 2014
- pelo Is Required for High Efficiency Viral Replication, 6th Author, 2014
- Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis, 8th Author, 2013
- Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling, 1st Author, 2013
- Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor-induced apoptosis of MCF-7 cells, Not mentioned, 2007
