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Zhongwen Chen
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: English, Chinese
Cell Signaling
Signal Transduction
Biochemistry
Molecular Biology
Biophysics
Physical Chemistry
Biological Systems
Cell Biology
Protein Interactions
Neuroscience
Areas of Focus
- Cell Signal Transduction
- Physical Chemistry of Biological Systems
Work Experience
- 2022-02~Present - Chinese Academy of Sciences, Shanghai Institute of Organic Chemistry - Researcher
- 2019-09~2022-01 - Fudan University - Junior Researcher
- 2018-02~2019-09 - University of California, Berkeley - Postdoctoral Researcher
- 2018-01~2018-02 - National University of Singapore - Visiting Scholar
Academic Background & Achievements
- 2012-08--2017-12 PhD: National University of Singapore
- 2009-08--2012-06 Master's: Southeast University
- 2005-08--2009-06 Bachelor's: Southeast University
Publications
- Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2, Dongmyung Oh, Zhongwen Chen, Kabir H Biswas, Funing Bai, Hui Ting Ong, Michael P Sheetz, Jay T Groves, 2022
- Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering, Zhongwen Chen, Kabir H Biswas, And Jay T Groves, 2022
- EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces, Wong, Joyce J, Chen, Zhongwen, Chung, Jean K, Groves, Jay T, Jardetzky, Theodore S, 2021
- Nanopore-mediated protein delivery enabling three-color single-molecule tracking in living cells, Chen, Zhongwen, Cao, Yuhong, Lin, ChunWei, Alvarez, Steven, Oh, Dongmyung, Yang, Peidong, Groves, Jay T, 2021
- Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility, Zhongwen Chen, Dongmyung Oh, Kabir Hassan Biswas, Ronen ZaidelBar, Jay T Groves, 2021
- Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity, Ravasio, Andrea, Myaing, Myint Z, Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Green, Adrianne C, Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T, Viasnoff, Virgile, 2020
- Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion, N O Alieva, A K Efremov, S Hu, D Oh, Zhongwen Chen, M Natarajan, H T Ong, A Jgou, G RometLemonne, J T Groves, M P Sheetz, J Yan, A D Bershadsky, 2019
- Multicomponent Supported Membrane Microarray for Monitoring Spatially Resolved Cellular Signaling Reactions, Biswas, Kabir H, Chen Zhongwen, Dubey, Alok Kumar, Oh, Dongmyung, Groves, Jay T, 2018
- EGFR family and Src family kinase interactions: mechanics matters?, Chen, Zhongwen, Oh, Dongmyung, Dubey, Alok Kumar, Yao, Mingxi, Yang, Beverly, Groves, Jay T, Sheetz, Michael, 2018
- Spatially modulated ephrinA1: EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility, Chen, Zhongwen, Oh, Dongmyung, Biswas, Kabir H, Yu, ChengHan, ZaidelBar, Ronen, Groves, Jay T, 2018
- Graphene oxide-based Fe2O3 hybrid enzyme mimetic with enhanced peroxidase and catalase-like activities, Song, Lina, Huang, Chao, Zhang, Wei, Ma, Ming, Chen, Zhongwen, Gu, Ning, Zhang, Yu, 2016
- Altering the response of intracellular reactive oxygen to magnetic nanoparticles using ultrasound and microbubbles, Yang, Fang, Li, Mingxi, Cui, Huating, Wang, Tuantuan, Chen, Zhongwen, Song, Lina, Gu, Zhuxiao, Zhang, Yu, Gu, Ning, 2015
- Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force, Yu, Chenghan, Rafiq, Nisha Bte Mohd, Cao, Fakun, Zhou, Yuhuan, Krishnasamy, Anitha, Biswas, Kabir Hassan, Ravasio, Andrea, Chen, Zhongwen, Wang, YuHsiu, Kawauchi, Keiko, Jones, Gareth E, Sheetz, Michael P, 2015
- Silver nanoparticles: a novel radiation sensitizer for glioma?, Liu, Peidang, Huang, Zhihai, Chen, Zhongwen, Xu, Ruizhi, Wu, Hao, Zang, Fengchao, Wang, Cailian, Gu, Ning, 2013
- In vitro biological effects of magnetic nanoparticles, Li Yan, Chen ZhongWen, Gu Ning, 2012
- Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity, Chen, Zhongwen, Yin, JunJie, Zhou, YuTing, Zhang, Yu, Song, Lina, Song, Mengjie, Hu, Sunling, Gu, Ning, 2012
Awards
- A method for simultaneous magnetic induction heating, imaging, and temperature measurement of tumor cells (2009): Invention Patent, 6th Author, Patent No: CN101601607
