Professor | 陈忠文 | 数字化转型顾问

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Name	陈忠文
Contact Information	chenzw@sioc.ac.cn
Language ability	英语, 中文
Province	上海

Upload Avatar (500 x 500)

Name

陈忠文

Contact Information

chenzw@sioc.ac.cn

Language ability

英语, 中文

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2012-08--2017-12 博士: 新加坡国立大学 2009-08--2012-06 硕士: 东南大学 2005-08--2009-06 本科: 东南大学
Work Experience	2022-02~现在 - 中国科学院上海有机化学研究所 - 研究员 2019-09~2022-01 - 复旦大学 - 青年研究员 2018-02~2019-09 - 加州大学伯克利分校 - 博士后 2018-01~2018-02 - 新加坡国立大学 - 访问学者
Awards	一种对肿瘤细胞同时进行磁感应加热、成像及测温的方法 (2009): 发明专利, 第6作者, 专利号: CN101601607

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2012-08--2017-12 博士: 新加坡国立大学
2009-08--2012-06 硕士: 东南大学
2005-08--2009-06 本科: 东南大学

Work Experience

2022-02~现在 - 中国科学院上海有机化学研究所 - 研究员
2019-09~2022-01 - 复旦大学 - 青年研究员
2018-02~2019-09 - 加州大学伯克利分校 - 博士后
2018-01~2018-02 - 新加坡国立大学 - 访问学者

Awards

一种对肿瘤细胞同时进行磁感应加热、成像及测温的方法 (2009): 发明专利, 第6作者, 专利号: CN101601607

Areas of Focus	细胞信号转导生物体系物理化学
Publications	Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2, Dongmyung Oh, Zhongwen Chen, Kabir H Biswas, Funing Bai, Hui Ting Ong, Michael P Sheetz, Jay T Groves, 2022 Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering, Zhongwen Chen, Kabir H Biswas, And Jay T Groves, 2022 EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces, Wong, Joyce J, Chen, Zhongwen, Chung, Jean K, Groves, Jay T, Jardetzky, Theodore S, 2021 Nanopore-mediated protein delivery enabling three-color single-molecule tracking in living cells, Chen, Zhongwen, Cao, Yuhong, Lin, ChunWei, Alvarez, Steven, Oh, Dongmyung, Yang, Peidong, Groves, Jay T, 2021 Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility, Zhongwen Chen, Dongmyung Oh, Kabir Hassan Biswas, Ronen ZaidelBar, Jay T Groves, 2021 Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity, Ravasio, Andrea, Myaing, Myint Z, Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Green, Adrianne C, Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T, Viasnoff, Virgile, 2020 Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion, N O Alieva, A K Efremov, S Hu, D Oh, Zhongwen Chen, M Natarajan, H T Ong, A Jgou, G RometLemonne, J T Groves, M P Sheetz, J Yan, A D Bershadsky, 2019 Multicomponent Supported Membrane Microarray for Monitoring Spatially Resolved Cellular Signaling Reactions, Biswas, Kabir H, Chen Zhongwen, Dubey, Alok Kumar, Oh, Dongmyung, Groves, Jay T, 2018 EGFR family and Src family kinase interactions: mechanics matters?, Chen, Zhongwen, Oh, Dongmyung, Dubey, Alok Kumar, Yao, Mingxi, Yang, Beverly, Groves, Jay T, Sheetz, Michael, 2018 Spatially modulated ephrinA1: EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility, Chen, Zhongwen, Oh, Dongmyung, Biswas, Kabir H, Yu, ChengHan, ZaidelBar, Ronen, Groves, Jay T, 2018 Graphene oxide-based Fe2O3 hybrid enzyme mimetic with enhanced peroxidase and catalase-like activities, Song, Lina, Huang, Chao, Zhang, Wei, Ma, Ming, Chen, Zhongwen, Gu, Ning, Zhang, Yu, 2016 Altering the response of intracellular reactive oxygen to magnetic nanoparticles using ultrasound and microbubbles, Yang, Fang, Li, Mingxi, Cui, Huating, Wang, Tuantuan, Chen, Zhongwen, Song, Lina, Gu, Zhuxiao, Zhang, Yu, Gu, Ning, 2015 Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force, Yu, Chenghan, Rafiq, Nisha Bte Mohd, Cao, Fakun, Zhou, Yuhuan, Krishnasamy, Anitha, Biswas, Kabir Hassan, Ravasio, Andrea, Chen, Zhongwen, Wang, YuHsiu, Kawauchi, Keiko, Jones, Gareth E, Sheetz, Michael P, 2015 Silver nanoparticles: a novel radiation sensitizer for glioma?, Liu, Peidang, Huang, Zhihai, Chen, Zhongwen, Xu, Ruizhi, Wu, Hao, Zang, Fengchao, Wang, Cailian, Gu, Ning, 2013 In vitro biological effects of magnetic nanoparticles, Li Yan, Chen ZhongWen, Gu Ning, 2012 Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity, Chen, Zhongwen, Yin, JunJie, Zhou, YuTing, Zhang, Yu, Song, Lina, Song, Mengjie, Hu, Sunling, Gu, Ning, 2012

Areas of Focus

细胞信号转导
生物体系物理化学

Publications

Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2, Dongmyung Oh, Zhongwen Chen, Kabir H Biswas, Funing Bai, Hui Ting Ong, Michael P Sheetz, Jay T Groves, 2022
Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering, Zhongwen Chen, Kabir H Biswas, And Jay T Groves, 2022
EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces, Wong, Joyce J, Chen, Zhongwen, Chung, Jean K, Groves, Jay T, Jardetzky, Theodore S, 2021
Nanopore-mediated protein delivery enabling three-color single-molecule tracking in living cells, Chen, Zhongwen, Cao, Yuhong, Lin, ChunWei, Alvarez, Steven, Oh, Dongmyung, Yang, Peidong, Groves, Jay T, 2021
Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility, Zhongwen Chen, Dongmyung Oh, Kabir Hassan Biswas, Ronen ZaidelBar, Jay T Groves, 2021
Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity, Ravasio, Andrea, Myaing, Myint Z, Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Green, Adrianne C, Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T, Viasnoff, Virgile, 2020
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion, N O Alieva, A K Efremov, S Hu, D Oh, Zhongwen Chen, M Natarajan, H T Ong, A Jgou, G RometLemonne, J T Groves, M P Sheetz, J Yan, A D Bershadsky, 2019
Multicomponent Supported Membrane Microarray for Monitoring Spatially Resolved Cellular Signaling Reactions, Biswas, Kabir H, Chen Zhongwen, Dubey, Alok Kumar, Oh, Dongmyung, Groves, Jay T, 2018
EGFR family and Src family kinase interactions: mechanics matters?, Chen, Zhongwen, Oh, Dongmyung, Dubey, Alok Kumar, Yao, Mingxi, Yang, Beverly, Groves, Jay T, Sheetz, Michael, 2018
Spatially modulated ephrinA1: EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility, Chen, Zhongwen, Oh, Dongmyung, Biswas, Kabir H, Yu, ChengHan, ZaidelBar, Ronen, Groves, Jay T, 2018
Graphene oxide-based Fe2O3 hybrid enzyme mimetic with enhanced peroxidase and catalase-like activities, Song, Lina, Huang, Chao, Zhang, Wei, Ma, Ming, Chen, Zhongwen, Gu, Ning, Zhang, Yu, 2016
Altering the response of intracellular reactive oxygen to magnetic nanoparticles using ultrasound and microbubbles, Yang, Fang, Li, Mingxi, Cui, Huating, Wang, Tuantuan, Chen, Zhongwen, Song, Lina, Gu, Zhuxiao, Zhang, Yu, Gu, Ning, 2015
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force, Yu, Chenghan, Rafiq, Nisha Bte Mohd, Cao, Fakun, Zhou, Yuhuan, Krishnasamy, Anitha, Biswas, Kabir Hassan, Ravasio, Andrea, Chen, Zhongwen, Wang, YuHsiu, Kawauchi, Keiko, Jones, Gareth E, Sheetz, Michael P, 2015
Silver nanoparticles: a novel radiation sensitizer for glioma?, Liu, Peidang, Huang, Zhihai, Chen, Zhongwen, Xu, Ruizhi, Wu, Hao, Zang, Fengchao, Wang, Cailian, Gu, Ning, 2013
In vitro biological effects of magnetic nanoparticles, Li Yan, Chen ZhongWen, Gu Ning, 2012
Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity, Chen, Zhongwen, Yin, JunJie, Zhou, YuTing, Zhang, Yu, Song, Lina, Song, Mengjie, Hu, Sunling, Gu, Ning, 2012

细胞信号信号转导生物化学分子生物学生物物理学物理化学生物体系细胞生物学蛋白质相互作用神经科学

崔香环 - 同济大学

杨洪全 - 上海师范大学

齐颖新 - 上海交通大学

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