Professor | Zilei Duan | Asia Growth Partners

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Name	Zilei Duan
Contact Information	duanzilei@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

Upload Avatar (500 x 500)

Name

Zilei Duan

Contact Information

duanzilei@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2012-09 to 2017-06 PhD: Kunming Institute of Zoology, Chinese Academy of Sciences 2008-09 to 2012-06 Bachelor: Shangqiu Normal University
Work Experience	2021-01 to Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher 2017-07 to 2020-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
Awards	National Science and Technology System Advanced Collective in Fighting COVID-19 (2021)

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2012-09 to 2017-06 PhD: Kunming Institute of Zoology, Chinese Academy of Sciences
2008-09 to 2012-06 Bachelor: Shangqiu Normal University

Work Experience

2021-01 to Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
2017-07 to 2020-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher

Awards

National Science and Technology System Advanced Collective in Fighting COVID-19 (2021)

Areas of Focus	Functional Proteomics of Natural Medicines Mechanisms of Bioactive Peptides and Diseases (Ulcerative Colitis, Alzheimer's Disease, Bacterial or Viral Infections, Stroke, etc.)
Publications	A designed antimicrobial peptide with potential ability against methicillin resistant Staphylococcus aureus., Yuan, Bingqian, Lu, Xiaoyu, Yang, Min, He, Qiyi, Cha, Zhuocen, Fang, Yaqun, Yang, Yan, Xu, Lei, Yan, Jingting, Lai, Ren, Wang, Aili, Yu, Xiaodong, Duan, Zilei., 2022 Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression., Chen, Xue, Deng, Suixin, Wang, Wenchao, Castiglione, Stefania, Duan, Zilei, Luo, Lei, Cianci, Francesca, Zhang, Xiaoxue, Xu, Jianglei, Li, Hao, Zhao, Jizong, Kamau, Peter Muiruri, Zhang, Zhiye, Mwangi, James, Li, Jiali, Shu, Yousheng, Hu, Xintian, Mazzanti, Michele, Lai, Ren., 2022 Shrew's venom quickly causes circulation disorder, analgesia and hypokinesia., Liao, Zhiyi, Tang, Xiaopeng, Chen, Wenlin, Jiang, Xuelong, Chen, Zhongzheng, He, Kai, Li, Quan, Duan, Zilei, He, Xiaoqin, Kamau, Peter Muiruri, Lv, Longbao, Zhang, Zhiye, Rong, Mingqiang, Lv, Qiumin, Lai, Ren., 2022 Role of LL-37 in thrombotic complications in patients with COVID-19., Duan, Zilei, Zhang, Juan, Chen, Xue, Liu, Ming, Zhao, Hongwen, Jin, Lin, Zhang, Zhiye, Luan, Ning, Meng, Ping, Wang, Jing, Tan, Zhaoxia, Li, Yaxiong, Deng, Guohong, Lai, Ren., 2022 SARS-CoV-2 M-pro inhibitors with antiviral activity in a transgenic mouse model., Qiao, Jingxin, Li, YueShan, Zeng, Rui, Liu, FengLiang, Luo, RongHua, Huang, Chong, Wang, YiFei, Zhang, Jie, Quan, Baoxue, Shen, Chenjian, Mao, Xin, Liu, Xinlei, Sun, Weining, Yang, Wei, Ni, Xincheng, Wang, Kai, Xu, Ling, Duan, ZiLei, Zou, QingCui, Zhang, HaiLin, Qu, Wang, Long, YangHaoPeng, Li, MingHua, Yang, RuiCheng, Liu, Xiaolong, You, Jing, Zhou, Yangli, Yao, Rui, Li, WenPei, Liu, JingMing, Chen, Pei, Liu, Yang, Lin, GuiFeng, Yang, Xin, Zou, Jun, Li, Linli, Hu, Yiguo, Lu, GuangWen, Li, WeiMin, Wei, YuQuan, Zheng, YongTang, Lei, Jian, Yang, Shengyong., 2021 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target., Xia, Bingqing, Shen, Xurui, He, Yang, Pan, Xiaoyan, Liu, FengLiang, Wang, Yi, Yang, Feipu, Fang, Sui, Wu, Yan, Duan, Zilei, Zuo, Xiaoli, Xie, Zhuqing, Jiang, Xiangrui, Xu, Ling, Chi, Hao, Li, Shuangqu, Meng, Qian, Zhou, Hu, Zhou, Yubo, Cheng, Xi, Xin, Xiaoming, Jin, Lin, Zhang, HaiLin, Yu, DanDan, Li, MingHua, Feng, XiaoLi, Chen, Jiekai, Jiang, Hualiang, Xiao, Gengfu, Zheng, YongTang, Zhang, LeiKe, Shen, Jingshan, Li, Jia, Gao, Zhaobing., 2021 Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice., Zhu, TengYu, Qiu, Huan, Cao, QiQi, Duan, ZiLei, Liu, FengLiang, Song, TianZhang, Liu, Yang, Fang, YaQun, Wu, GuangMing, Zheng, YongTang, Ding, WenJun, Lai, Ren, Jin, Lin., 2021 Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study., Tian, RenRong, Yang, CuiXian, Zhang, Mi, Feng, XiaoLi, Luo, RongHua, Duan, ZiLei, Li, JianJian, Liu, JiaFa, Yu, DanDan, Xu, Ling, Zheng, HongYi, Li, MingHua, Fan, HongLi, Wang, JiaLi, Dong, XingQi, Zheng, YongTang., 2021 Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation., Liu, FengLiang, Wu, Kaixin, Sun, Jiaoyang, Duan, Zilei, Quan, Xiongzhi, Kuang, Junqi, Chu, Shilong, Pang, Wei, Gao, Han, Xu, Ling, Li, YingChang, Zhang, HaiLin, Wang, XueHui, Luo, RongHua, Feng, XiaoLi, Schoeler, Hans R, Chen, Xinwen, Pei, Duanqing, Wu, Guangming, Zheng, YongTang, Chen, Jiekai., 2021 High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease., Li, Yan, Zhang, Jinyong, Duan, Zilei, Wang, Ning, Sun, Xiangcheng, Zhang, Yanjing, Fu, Li, Liu, Kaiyun, Yang, Yongjun, Pan, Shulei, Shi, Yun, Zeng, Hao, Guo, Gang, Lai, Ren, Zou, Quanming., 2021 Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models., Wang, Gan, Yang, MengLi, Duan, ZiLei, Liu, FengLiang, Jin, Lin, Long, ChengBo, Zhang, Min, Tang, XiaoPeng, Xu, Ling, Li, YingChang, Kamau, Peter Muiruri, Yang, Lian, Liu, HongQi, Xu, JingWen, Chen, JieKai, Zheng, YongTang, Peng, XiaoZhong, Lai, Ren., 2021 The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation., Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai., 2020 Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis., Tang, Xiaopeng, Chen, Mengrou, Duan, Zilei, Mwangi, James, Li, Pengpeng, Lai, Ren., 2018 Antimicrobial peptide LL-37 forms complex with bacterial DNA to facilitate blood translocation of bacterial DNA and aggravate ulcerative colitis., Duan, Zilei, Fang, Yaqun, Sun, Yang, Luan, Ning, Chen, Xue, Chen, Mengrou, Han, Yajun, Yin, Yizhu, Mwangi, James, Niu, Junkun, Wang, Kunhua, Miao, Yinglei, Zhang, Zhiye, Lai, Ren., 2018 An inhibitor peptide of toll-like receptor 2 shows therapeutic potential for allergic conjunctivitis., Xu, Cheng, He, Xiaoqin, Liu, Weihui, Chen, Yan, Zhou, Chunling, Duan, Zilei, Lu, Qiumin, Yan, Xiuwen, Zhang, Zhiye, Zheng, Ruiqiang., 2017 Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi., Luan, Ning, Zhou, Chunling, Li, Pengpeng, Ombati, Rose, Yan, Xiuwen, Mo, Guoxiang, Rong, Mingqiang, Lai, Ren, Duan, Zilei, Zheng, Ruiqiang., 2017 A short peptide from frog skin accelerates diabetic wound healing., Liu, Han, Duan, Zilei, Tang, Jing, Lv, Qiumin, Rong, Mingqiang, Lai, Ren., 2014 A novel 26RFa peptide containing both analgesic and anti-inflammatory functions from Chinese tree shrew., Zhu, Yuqin, Duan, Zilei, Mo, Guoxiang, Shen, Chuanbin, Lv, Longbao, Chen, Wenlin, Lai, Ren., 2014 A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris., Zhang, Zhiye, Mu, Lixian, Tang, Jing, Duan, Zilei, Wang, Fengyu, Wei, Lin, Rong, Mingqiang, Lai, Ren., 2013

Areas of Focus

Functional Proteomics of Natural Medicines
Mechanisms of Bioactive Peptides and Diseases (Ulcerative Colitis, Alzheimer's Disease, Bacterial or Viral Infections, Stroke, etc.)

Publications

A designed antimicrobial peptide with potential ability against methicillin resistant Staphylococcus aureus., Yuan, Bingqian, Lu, Xiaoyu, Yang, Min, He, Qiyi, Cha, Zhuocen, Fang, Yaqun, Yang, Yan, Xu, Lei, Yan, Jingting, Lai, Ren, Wang, Aili, Yu, Xiaodong, Duan, Zilei., 2022
Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression., Chen, Xue, Deng, Suixin, Wang, Wenchao, Castiglione, Stefania, Duan, Zilei, Luo, Lei, Cianci, Francesca, Zhang, Xiaoxue, Xu, Jianglei, Li, Hao, Zhao, Jizong, Kamau, Peter Muiruri, Zhang, Zhiye, Mwangi, James, Li, Jiali, Shu, Yousheng, Hu, Xintian, Mazzanti, Michele, Lai, Ren., 2022
Shrew's venom quickly causes circulation disorder, analgesia and hypokinesia., Liao, Zhiyi, Tang, Xiaopeng, Chen, Wenlin, Jiang, Xuelong, Chen, Zhongzheng, He, Kai, Li, Quan, Duan, Zilei, He, Xiaoqin, Kamau, Peter Muiruri, Lv, Longbao, Zhang, Zhiye, Rong, Mingqiang, Lv, Qiumin, Lai, Ren., 2022
Role of LL-37 in thrombotic complications in patients with COVID-19., Duan, Zilei, Zhang, Juan, Chen, Xue, Liu, Ming, Zhao, Hongwen, Jin, Lin, Zhang, Zhiye, Luan, Ning, Meng, Ping, Wang, Jing, Tan, Zhaoxia, Li, Yaxiong, Deng, Guohong, Lai, Ren., 2022
SARS-CoV-2 M-pro inhibitors with antiviral activity in a transgenic mouse model., Qiao, Jingxin, Li, YueShan, Zeng, Rui, Liu, FengLiang, Luo, RongHua, Huang, Chong, Wang, YiFei, Zhang, Jie, Quan, Baoxue, Shen, Chenjian, Mao, Xin, Liu, Xinlei, Sun, Weining, Yang, Wei, Ni, Xincheng, Wang, Kai, Xu, Ling, Duan, ZiLei, Zou, QingCui, Zhang, HaiLin, Qu, Wang, Long, YangHaoPeng, Li, MingHua, Yang, RuiCheng, Liu, Xiaolong, You, Jing, Zhou, Yangli, Yao, Rui, Li, WenPei, Liu, JingMing, Chen, Pei, Liu, Yang, Lin, GuiFeng, Yang, Xin, Zou, Jun, Li, Linli, Hu, Yiguo, Lu, GuangWen, Li, WeiMin, Wei, YuQuan, Zheng, YongTang, Lei, Jian, Yang, Shengyong., 2021
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target., Xia, Bingqing, Shen, Xurui, He, Yang, Pan, Xiaoyan, Liu, FengLiang, Wang, Yi, Yang, Feipu, Fang, Sui, Wu, Yan, Duan, Zilei, Zuo, Xiaoli, Xie, Zhuqing, Jiang, Xiangrui, Xu, Ling, Chi, Hao, Li, Shuangqu, Meng, Qian, Zhou, Hu, Zhou, Yubo, Cheng, Xi, Xin, Xiaoming, Jin, Lin, Zhang, HaiLin, Yu, DanDan, Li, MingHua, Feng, XiaoLi, Chen, Jiekai, Jiang, Hualiang, Xiao, Gengfu, Zheng, YongTang, Zhang, LeiKe, Shen, Jingshan, Li, Jia, Gao, Zhaobing., 2021
Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice., Zhu, TengYu, Qiu, Huan, Cao, QiQi, Duan, ZiLei, Liu, FengLiang, Song, TianZhang, Liu, Yang, Fang, YaQun, Wu, GuangMing, Zheng, YongTang, Ding, WenJun, Lai, Ren, Jin, Lin., 2021
Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study., Tian, RenRong, Yang, CuiXian, Zhang, Mi, Feng, XiaoLi, Luo, RongHua, Duan, ZiLei, Li, JianJian, Liu, JiaFa, Yu, DanDan, Xu, Ling, Zheng, HongYi, Li, MingHua, Fan, HongLi, Wang, JiaLi, Dong, XingQi, Zheng, YongTang., 2021
Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation., Liu, FengLiang, Wu, Kaixin, Sun, Jiaoyang, Duan, Zilei, Quan, Xiongzhi, Kuang, Junqi, Chu, Shilong, Pang, Wei, Gao, Han, Xu, Ling, Li, YingChang, Zhang, HaiLin, Wang, XueHui, Luo, RongHua, Feng, XiaoLi, Schoeler, Hans R, Chen, Xinwen, Pei, Duanqing, Wu, Guangming, Zheng, YongTang, Chen, Jiekai., 2021
High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease., Li, Yan, Zhang, Jinyong, Duan, Zilei, Wang, Ning, Sun, Xiangcheng, Zhang, Yanjing, Fu, Li, Liu, Kaiyun, Yang, Yongjun, Pan, Shulei, Shi, Yun, Zeng, Hao, Guo, Gang, Lai, Ren, Zou, Quanming., 2021
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models., Wang, Gan, Yang, MengLi, Duan, ZiLei, Liu, FengLiang, Jin, Lin, Long, ChengBo, Zhang, Min, Tang, XiaoPeng, Xu, Ling, Li, YingChang, Kamau, Peter Muiruri, Yang, Lian, Liu, HongQi, Xu, JingWen, Chen, JieKai, Zheng, YongTang, Peng, XiaoZhong, Lai, Ren., 2021
The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation., Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai., 2020
Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis., Tang, Xiaopeng, Chen, Mengrou, Duan, Zilei, Mwangi, James, Li, Pengpeng, Lai, Ren., 2018
Antimicrobial peptide LL-37 forms complex with bacterial DNA to facilitate blood translocation of bacterial DNA and aggravate ulcerative colitis., Duan, Zilei, Fang, Yaqun, Sun, Yang, Luan, Ning, Chen, Xue, Chen, Mengrou, Han, Yajun, Yin, Yizhu, Mwangi, James, Niu, Junkun, Wang, Kunhua, Miao, Yinglei, Zhang, Zhiye, Lai, Ren., 2018
An inhibitor peptide of toll-like receptor 2 shows therapeutic potential for allergic conjunctivitis., Xu, Cheng, He, Xiaoqin, Liu, Weihui, Chen, Yan, Zhou, Chunling, Duan, Zilei, Lu, Qiumin, Yan, Xiuwen, Zhang, Zhiye, Zheng, Ruiqiang., 2017
Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi., Luan, Ning, Zhou, Chunling, Li, Pengpeng, Ombati, Rose, Yan, Xiuwen, Mo, Guoxiang, Rong, Mingqiang, Lai, Ren, Duan, Zilei, Zheng, Ruiqiang., 2017
A short peptide from frog skin accelerates diabetic wound healing., Liu, Han, Duan, Zilei, Tang, Jing, Lv, Qiumin, Rong, Mingqiang, Lai, Ren., 2014
A novel 26RFa peptide containing both analgesic and anti-inflammatory functions from Chinese tree shrew., Zhu, Yuqin, Duan, Zilei, Mo, Guoxiang, Shen, Chuanbin, Lv, Longbao, Chen, Wenlin, Lai, Ren., 2014
A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris., Zhang, Zhiye, Mu, Lixian, Tang, Jing, Duan, Zilei, Wang, Fengyu, Wei, Lin, Rong, Mingqiang, Lai, Ren., 2013

Proteomics Natural Medicines Bioactive Peptides Ulcerative Colitis Alzheimer'S Disease Bacterial Infections Viral Infections Stroke Disease Mechanisms Functional Proteins

Kefu Liu - Central South University

Kefu Liu - Central South University

Rui Bi - University of Chinese Academy of Sciences

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