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Zilei Duan
Life Science
University of Chinese Academy of Sciences
Yunnan
Language: Chinese, English
Proteomics
Natural Medicines
Bioactive Peptides
Ulcerative Colitis
Alzheimer'S Disease
Bacterial Infections
Viral Infections
Stroke
Disease Mechanisms
Functional Proteins
Areas of Focus
- Functional Proteomics of Natural Medicines
- Mechanisms of Bioactive Peptides and Diseases (Ulcerative Colitis, Alzheimer's Disease, Bacterial or Viral Infections, Stroke, etc.)
Work Experience
- 2021-01 to Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
- 2017-07 to 2020-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2012-09 to 2017-06 PhD: Kunming Institute of Zoology, Chinese Academy of Sciences
- 2008-09 to 2012-06 Bachelor: Shangqiu Normal University
Publications
- A designed antimicrobial peptide with potential ability against methicillin resistant Staphylococcus aureus., Yuan, Bingqian, Lu, Xiaoyu, Yang, Min, He, Qiyi, Cha, Zhuocen, Fang, Yaqun, Yang, Yan, Xu, Lei, Yan, Jingting, Lai, Ren, Wang, Aili, Yu, Xiaodong, Duan, Zilei., 2022
- Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression., Chen, Xue, Deng, Suixin, Wang, Wenchao, Castiglione, Stefania, Duan, Zilei, Luo, Lei, Cianci, Francesca, Zhang, Xiaoxue, Xu, Jianglei, Li, Hao, Zhao, Jizong, Kamau, Peter Muiruri, Zhang, Zhiye, Mwangi, James, Li, Jiali, Shu, Yousheng, Hu, Xintian, Mazzanti, Michele, Lai, Ren., 2022
- Shrew's venom quickly causes circulation disorder, analgesia and hypokinesia., Liao, Zhiyi, Tang, Xiaopeng, Chen, Wenlin, Jiang, Xuelong, Chen, Zhongzheng, He, Kai, Li, Quan, Duan, Zilei, He, Xiaoqin, Kamau, Peter Muiruri, Lv, Longbao, Zhang, Zhiye, Rong, Mingqiang, Lv, Qiumin, Lai, Ren., 2022
- Role of LL-37 in thrombotic complications in patients with COVID-19., Duan, Zilei, Zhang, Juan, Chen, Xue, Liu, Ming, Zhao, Hongwen, Jin, Lin, Zhang, Zhiye, Luan, Ning, Meng, Ping, Wang, Jing, Tan, Zhaoxia, Li, Yaxiong, Deng, Guohong, Lai, Ren., 2022
- SARS-CoV-2 M-pro inhibitors with antiviral activity in a transgenic mouse model., Qiao, Jingxin, Li, YueShan, Zeng, Rui, Liu, FengLiang, Luo, RongHua, Huang, Chong, Wang, YiFei, Zhang, Jie, Quan, Baoxue, Shen, Chenjian, Mao, Xin, Liu, Xinlei, Sun, Weining, Yang, Wei, Ni, Xincheng, Wang, Kai, Xu, Ling, Duan, ZiLei, Zou, QingCui, Zhang, HaiLin, Qu, Wang, Long, YangHaoPeng, Li, MingHua, Yang, RuiCheng, Liu, Xiaolong, You, Jing, Zhou, Yangli, Yao, Rui, Li, WenPei, Liu, JingMing, Chen, Pei, Liu, Yang, Lin, GuiFeng, Yang, Xin, Zou, Jun, Li, Linli, Hu, Yiguo, Lu, GuangWen, Li, WeiMin, Wei, YuQuan, Zheng, YongTang, Lei, Jian, Yang, Shengyong., 2021
- SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target., Xia, Bingqing, Shen, Xurui, He, Yang, Pan, Xiaoyan, Liu, FengLiang, Wang, Yi, Yang, Feipu, Fang, Sui, Wu, Yan, Duan, Zilei, Zuo, Xiaoli, Xie, Zhuqing, Jiang, Xiangrui, Xu, Ling, Chi, Hao, Li, Shuangqu, Meng, Qian, Zhou, Hu, Zhou, Yubo, Cheng, Xi, Xin, Xiaoming, Jin, Lin, Zhang, HaiLin, Yu, DanDan, Li, MingHua, Feng, XiaoLi, Chen, Jiekai, Jiang, Hualiang, Xiao, Gengfu, Zheng, YongTang, Zhang, LeiKe, Shen, Jingshan, Li, Jia, Gao, Zhaobing., 2021
- Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice., Zhu, TengYu, Qiu, Huan, Cao, QiQi, Duan, ZiLei, Liu, FengLiang, Song, TianZhang, Liu, Yang, Fang, YaQun, Wu, GuangMing, Zheng, YongTang, Ding, WenJun, Lai, Ren, Jin, Lin., 2021
- Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study., Tian, RenRong, Yang, CuiXian, Zhang, Mi, Feng, XiaoLi, Luo, RongHua, Duan, ZiLei, Li, JianJian, Liu, JiaFa, Yu, DanDan, Xu, Ling, Zheng, HongYi, Li, MingHua, Fan, HongLi, Wang, JiaLi, Dong, XingQi, Zheng, YongTang., 2021
- Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation., Liu, FengLiang, Wu, Kaixin, Sun, Jiaoyang, Duan, Zilei, Quan, Xiongzhi, Kuang, Junqi, Chu, Shilong, Pang, Wei, Gao, Han, Xu, Ling, Li, YingChang, Zhang, HaiLin, Wang, XueHui, Luo, RongHua, Feng, XiaoLi, Schoeler, Hans R, Chen, Xinwen, Pei, Duanqing, Wu, Guangming, Zheng, YongTang, Chen, Jiekai., 2021
- High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease., Li, Yan, Zhang, Jinyong, Duan, Zilei, Wang, Ning, Sun, Xiangcheng, Zhang, Yanjing, Fu, Li, Liu, Kaiyun, Yang, Yongjun, Pan, Shulei, Shi, Yun, Zeng, Hao, Guo, Gang, Lai, Ren, Zou, Quanming., 2021
- Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models., Wang, Gan, Yang, MengLi, Duan, ZiLei, Liu, FengLiang, Jin, Lin, Long, ChengBo, Zhang, Min, Tang, XiaoPeng, Xu, Ling, Li, YingChang, Kamau, Peter Muiruri, Yang, Lian, Liu, HongQi, Xu, JingWen, Chen, JieKai, Zheng, YongTang, Peng, XiaoZhong, Lai, Ren., 2021
- The 14-3-3ζ–c-Src–integrin-β3 complex is vital for platelet activation., Chuanbin Shen, Ming Liu, Runjia Xu, Gan Wang, June Li, Pingguo Chen, Wenjing Ma, James Mwangi, Qiumin Lu, Zilei Duan, Zhiye Zhang, Fatima Zohra Dahmani, Daniel Thomas Mackeigan, Heyu Ni, Ren Lai., 2020
- Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis., Tang, Xiaopeng, Chen, Mengrou, Duan, Zilei, Mwangi, James, Li, Pengpeng, Lai, Ren., 2018
- Antimicrobial peptide LL-37 forms complex with bacterial DNA to facilitate blood translocation of bacterial DNA and aggravate ulcerative colitis., Duan, Zilei, Fang, Yaqun, Sun, Yang, Luan, Ning, Chen, Xue, Chen, Mengrou, Han, Yajun, Yin, Yizhu, Mwangi, James, Niu, Junkun, Wang, Kunhua, Miao, Yinglei, Zhang, Zhiye, Lai, Ren., 2018
- An inhibitor peptide of toll-like receptor 2 shows therapeutic potential for allergic conjunctivitis., Xu, Cheng, He, Xiaoqin, Liu, Weihui, Chen, Yan, Zhou, Chunling, Duan, Zilei, Lu, Qiumin, Yan, Xiuwen, Zhang, Zhiye, Zheng, Ruiqiang., 2017
- Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi., Luan, Ning, Zhou, Chunling, Li, Pengpeng, Ombati, Rose, Yan, Xiuwen, Mo, Guoxiang, Rong, Mingqiang, Lai, Ren, Duan, Zilei, Zheng, Ruiqiang., 2017
- A short peptide from frog skin accelerates diabetic wound healing., Liu, Han, Duan, Zilei, Tang, Jing, Lv, Qiumin, Rong, Mingqiang, Lai, Ren., 2014
- A novel 26RFa peptide containing both analgesic and anti-inflammatory functions from Chinese tree shrew., Zhu, Yuqin, Duan, Zilei, Mo, Guoxiang, Shen, Chuanbin, Lv, Longbao, Chen, Wenlin, Lai, Ren., 2014
- A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris., Zhang, Zhiye, Mu, Lixian, Tang, Jing, Duan, Zilei, Wang, Fengyu, Wei, Lin, Rong, Mingqiang, Lai, Ren., 2013
Awards
- National Science and Technology System Advanced Collective in Fighting COVID-19 (2021)
