Professor | Bo Feng | Asia Growth Partners

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Name	Bo Feng
Contact Information	b.feng@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Bo Feng

Contact Information

b.feng@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2009-09--2014-12 PhD: Zhejiang University 2005-09--2009-06 Bachelor's: Shanghai Jiao Tong University
Work Experience	2017-07~2021-08 - University of California, San Diego - Postdoctoral Researcher 2015-01~2017-02 - Zhejiang University - Postdoctoral Researcher 2009-09~2014-12 - Zhejiang University - PhD 2005-09~2009-06 - Shanghai Jiao Tong University - Bachelor's

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2009-09--2014-12 PhD: Zhejiang University
2005-09--2009-06 Bachelor's: Shanghai Jiao Tong University

Work Experience

2017-07~2021-08 - University of California, San Diego - Postdoctoral Researcher
2015-01~2017-02 - Zhejiang University - Postdoctoral Researcher
2009-09~2014-12 - Zhejiang University - PhD
2005-09~2009-06 - Shanghai Jiao Tong University - Bachelor's

Areas of Focus	Research on the pathogenesis of neurodegenerative diseases and drug development Molecular mechanism of synaptic development
Publications	Planar cell polarity signaling components are a direct target of beta-amyloid-associated degeneration of glutamatergic synapses, First Author, 2021 Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex, Third Author, 2021 Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures, Second Author, 2020 LRRK2 mediates axon development by regulating Frizzled3 phosphorylation and growth cone—growth cone communication, Third Author, 2020 Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility, Second Author, 2020 Microglial displacement of GABAergic synapses has endogenous protective function in generation of complex febrile seizures, Third Author, 2018 Correction to: Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2018 Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures (vol 30, pg 913, 2014), Third Author, 2018 Transient increase of interleukin-1 beta after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling, First Author, 2016 Generation of Febrile Seizures and Subsequent Epileptogenesis, First Author, 2016 Early hypoactivity of hippocampal rhythms during epileptogenesis after prolonged febrile seizures in freely-moving rats, First Author, 2015 Protective effect of carnosine on febrile seizures in immature mice, Third Author, 2015 Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2014 Prolonged febrile seizures increase seizure susceptibility in adulthood via a cascade increase of IL-1 beta and CB1R signaling, Second Author, 2014 Dysfunction of thermoregulation contributes to the generation of hyperthermia-induced seizures, First Author, 2014 Transient augment of IL-1 beta promotes seizure susceptibility via upregulating CB1 receptor in prolonged febrile seizures, Second Author, 2013 Reactive astrocytes contribute to increased epileptic susceptibility induced by subthreshold dose of pilocarpine, Third Author, 2012 Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010 Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010

Areas of Focus

Research on the pathogenesis of neurodegenerative diseases and drug development
Molecular mechanism of synaptic development

Publications

Planar cell polarity signaling components are a direct target of beta-amyloid-associated degeneration of glutamatergic synapses, First Author, 2021
Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex, Third Author, 2021
Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures, Second Author, 2020
LRRK2 mediates axon development by regulating Frizzled3 phosphorylation and growth cone—growth cone communication, Third Author, 2020
Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility, Second Author, 2020
Microglial displacement of GABAergic synapses has endogenous protective function in generation of complex febrile seizures, Third Author, 2018
Correction to: Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2018
Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures (vol 30, pg 913, 2014), Third Author, 2018
Transient increase of interleukin-1 beta after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling, First Author, 2016
Generation of Febrile Seizures and Subsequent Epileptogenesis, First Author, 2016
Early hypoactivity of hippocampal rhythms during epileptogenesis after prolonged febrile seizures in freely-moving rats, First Author, 2015
Protective effect of carnosine on febrile seizures in immature mice, Third Author, 2015
Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2014
Prolonged febrile seizures increase seizure susceptibility in adulthood via a cascade increase of IL-1 beta and CB1R signaling, Second Author, 2014
Dysfunction of thermoregulation contributes to the generation of hyperthermia-induced seizures, First Author, 2014
Transient augment of IL-1 beta promotes seizure susceptibility via upregulating CB1 receptor in prolonged febrile seizures, Second Author, 2013
Reactive astrocytes contribute to increased epileptic susceptibility induced by subthreshold dose of pilocarpine, Third Author, 2012
Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010
Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010

Neurodegenerative Diseases Pathogenesis Drug Development Synaptic Development Molecular Mechanism Neuroscience Neurobiology Cell Biology Developmental Biology Caspase-1 Inhibitors

Jun Zhang - Shanghai Normal University

Caiqin Hao - Shanghai Normal University

Lu Qing - Shanghai Jiao Tong University

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