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Bo Feng
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Neurodegenerative Diseases
Pathogenesis
Drug Development
Synaptic Development
Molecular Mechanism
Neuroscience
Neurobiology
Cell Biology
Developmental Biology
Caspase-1 Inhibitors
Areas of Focus
- Research on the pathogenesis of neurodegenerative diseases and drug development
- Molecular mechanism of synaptic development
Work Experience
- 2017-07~2021-08 - University of California, San Diego - Postdoctoral Researcher
- 2015-01~2017-02 - Zhejiang University - Postdoctoral Researcher
- 2009-09~2014-12 - Zhejiang University - PhD
- 2005-09~2009-06 - Shanghai Jiao Tong University - Bachelor's
Academic Background & Achievements
- 2009-09--2014-12 PhD: Zhejiang University
- 2005-09--2009-06 Bachelor's: Shanghai Jiao Tong University
Publications
- Planar cell polarity signaling components are a direct target of beta-amyloid-associated degeneration of glutamatergic synapses, First Author, 2021
- Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex, Third Author, 2021
- Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures, Second Author, 2020
- LRRK2 mediates axon development by regulating Frizzled3 phosphorylation and growth cone—growth cone communication, Third Author, 2020
- Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility, Second Author, 2020
- Microglial displacement of GABAergic synapses has endogenous protective function in generation of complex febrile seizures, Third Author, 2018
- Correction to: Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2018
- Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures (vol 30, pg 913, 2014), Third Author, 2018
- Transient increase of interleukin-1 beta after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling, First Author, 2016
- Generation of Febrile Seizures and Subsequent Epileptogenesis, First Author, 2016
- Early hypoactivity of hippocampal rhythms during epileptogenesis after prolonged febrile seizures in freely-moving rats, First Author, 2015
- Protective effect of carnosine on febrile seizures in immature mice, Third Author, 2015
- Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures, Third Author, 2014
- Prolonged febrile seizures increase seizure susceptibility in adulthood via a cascade increase of IL-1 beta and CB1R signaling, Second Author, 2014
- Dysfunction of thermoregulation contributes to the generation of hyperthermia-induced seizures, First Author, 2014
- Transient augment of IL-1 beta promotes seizure susceptibility via upregulating CB1 receptor in prolonged febrile seizures, Second Author, 2013
- Reactive astrocytes contribute to increased epileptic susceptibility induced by subthreshold dose of pilocarpine, Third Author, 2012
- Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010
- Ameliorating effect of histamine on impairment of cued fear extinction induced by morphine withdrawal in histidine decarboxylase gene knockout mice, Third Author, 2010
