Professor | Yao-Xi He | Asia Growth Partners

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Name	Yao-Xi He
Contact Information	heyaoxi@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

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Name

Yao-Xi He

Contact Information

heyaoxi@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2014-09 to 2019-06 Ph.D. in Science: University of Chinese Academy of Sciences 2010-09 to 2014-07 Bachelor's in Science: Yunnan University

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2014-09 to 2019-06 Ph.D. in Science: University of Chinese Academy of Sciences
2010-09 to 2014-07 Bachelor's in Science: Yunnan University

Areas of Focus	Human adaptive evolution Genomic diversity
Publications	High Arterial Oxygen Saturation in the Acclimatized Lowlanders Living at High Altitude, First Author, 2023 Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans, Second Author, 2023 Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans, Corresponding Author, 2023 Polygenic adaptation leads to a higher reproductive fitness of native Tibetans at high altitude, Corresponding Author, 2023 Exploring the primate genome: Unraveling the mysteries of evolution and human disease, First Author, 2023 Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification, Fifth Author, 2022 Genetic adaptation of skin pigmentation in highland Tibetans, Collaborative Author, 2022 A Late Pleistocene human genome from Southwest China, Corresponding Author, 2022 Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations, First Author, 2021 Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation, Third Author, 2020 Association study of genomic structural variants with high-altitude adaptation phenotypes in Tibetans, Second Author, 2020 Phenotypic and Genetic Study on High-altitude Adaptation of Tibetan Populations, First Author, 2019 Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants, First Author, 2019 The Transcriptomic Landscape of Yaks Reveals Molecular Pathways for High Altitude Adaptation, Third Author, 2019 Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys, Second Author, 2019 Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia, First Author, 2018 EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production, Second Author, 2017 GCH1 plays a role in the high-altitude adaptation of Tibetans, Second Author, 2017 Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia, Third Author, 2017 Cross-altitude analysis suggests a turning point at the elevation of 4,500m for polycythemia prevalence in tibetans., Second Author, 2017 HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans, Ninth Author, 2016

Areas of Focus

Human adaptive evolution
Genomic diversity

Publications

High Arterial Oxygen Saturation in the Acclimatized Lowlanders Living at High Altitude, First Author, 2023
Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans, Second Author, 2023
Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans, Corresponding Author, 2023
Polygenic adaptation leads to a higher reproductive fitness of native Tibetans at high altitude, Corresponding Author, 2023
Exploring the primate genome: Unraveling the mysteries of evolution and human disease, First Author, 2023
Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification, Fifth Author, 2022
Genetic adaptation of skin pigmentation in highland Tibetans, Collaborative Author, 2022
A Late Pleistocene human genome from Southwest China, Corresponding Author, 2022
Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations, First Author, 2021
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation, Third Author, 2020
Association study of genomic structural variants with high-altitude adaptation phenotypes in Tibetans, Second Author, 2020
Phenotypic and Genetic Study on High-altitude Adaptation of Tibetan Populations, First Author, 2019
Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants, First Author, 2019
The Transcriptomic Landscape of Yaks Reveals Molecular Pathways for High Altitude Adaptation, Third Author, 2019
Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys, Second Author, 2019
Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia, First Author, 2018
EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production, Second Author, 2017
GCH1 plays a role in the high-altitude adaptation of Tibetans, Second Author, 2017
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia, Third Author, 2017
Cross-altitude analysis suggests a turning point at the elevation of 4,500m for polycythemia prevalence in tibetans., Second Author, 2017
HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans, Ninth Author, 2016

Evolution Adaptation Genomics Diversity Human Genetic Phenotype Tibetans High-Altitude Research

Ziwei Yin - Shanghai Normal University

Jun Xu - Shanghai Jiao Tong University

Xiaodan Wang - East China Normal University

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