Professor | Hui Jingyi | Asia Growth Partners

Name	Hui Jingyi
Contact Information	jyhui@sibs.ac.cn
Language ability	English, German, Chinese
Province	Shanghai

Name

Hui Jingyi

Contact Information

jyhui@sibs.ac.cn

Language ability

English, German, Chinese

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1999-09--2003-05 PhD: Justus Liebig University Giessen 1998-08--1999-08 Master's: Free University of Berlin 1989-09--1993-07 Bachelor's: Fudan University
Work Experience	2008-06~Present - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Group Leader 2006-11~2008-05 - Friedrich-Alexander-Universität Erlangen-Nürnberg - Postdoctoral Researcher 2003-06~2006-10 - Justus Liebig University Giessen - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1999-09--2003-05 PhD: Justus Liebig University Giessen
1998-08--1999-08 Master's: Free University of Berlin
1989-09--1993-07 Bachelor's: Fudan University

Work Experience

2008-06~Present - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Group Leader
2006-11~2008-05 - Friedrich-Alexander-Universität Erlangen-Nürnberg - Postdoctoral Researcher
2003-06~2006-10 - Justus Liebig University Giessen - Postdoctoral Researcher

Areas of Focus	Regulation and function of mRNA splicing in mammalian cells
Publications	Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway, Corresponding Author, 2022 5 ' UTR SNP of FGF13 causes translational defect and intellectual disability, Corresponding Author, 2021 Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes, 4th Author, 2021 Msi2-mediated MiR7a-1 processing repression promotes myogenesis, Corresponding Author, 2021 Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models, Corresponding Author, 2021 QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer, Corresponding Author, 2021 LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice, 13th Author, 2020 Auto-regulatory feedback by RNA-binding proteins, 3rd Author, 2019 Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA, Corresponding Author, 2019 Opposing roles of mir-294 and mbnl1/2 in shaping the gene regulatory network of embryonic stem cells, Corresponding Author, 2018 SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling, Corresponding Author, 2017 The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis, 21st Author, 2017 Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis, 5th Author, 2017 QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis, 5th Author, 2016 Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in glioblastoma multiforme, Corresponding Author, 2015 The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing, 11th Author, 2014 YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts, Corresponding Author, 2012 HnRNP L-mediated regulation of mammalian alternative splicing by interference with splice site recognition, 2nd Author, 2010 The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing, 3rd Author, 2010 Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing ▿ ‡, 6th Author, 2009 Diverse roles of hnRNP L in mammalian mRNA processing: A combined microarray and RNAi analysis, 3rd Author, 2008 HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats, Not mentioned, 2003 Novel function role of CA repeats and hnRNP L in RNA stability, 1st Author, 2003 Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing, 11th Author

Areas of Focus

Regulation and function of mRNA splicing in mammalian cells

Publications

Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway, Corresponding Author, 2022
5 ' UTR SNP of FGF13 causes translational defect and intellectual disability, Corresponding Author, 2021
Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes, 4th Author, 2021
Msi2-mediated MiR7a-1 processing repression promotes myogenesis, Corresponding Author, 2021
Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models, Corresponding Author, 2021
QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer, Corresponding Author, 2021
LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice, 13th Author, 2020
Auto-regulatory feedback by RNA-binding proteins, 3rd Author, 2019
Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA, Corresponding Author, 2019
Opposing roles of mir-294 and mbnl1/2 in shaping the gene regulatory network of embryonic stem cells, Corresponding Author, 2018
SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling, Corresponding Author, 2017
The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis, 21st Author, 2017
Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis, 5th Author, 2017
QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis, 5th Author, 2016
Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in glioblastoma multiforme, Corresponding Author, 2015
The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing, 11th Author, 2014
YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts, Corresponding Author, 2012
HnRNP L-mediated regulation of mammalian alternative splicing by interference with splice site recognition, 2nd Author, 2010
The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing, 3rd Author, 2010
Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing ▿ ‡, 6th Author, 2009
Diverse roles of hnRNP L in mammalian mRNA processing: A combined microarray and RNAi analysis, 3rd Author, 2008
HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats, Not mentioned, 2003
Novel function role of CA repeats and hnRNP L in RNA stability, 1st Author, 2003
Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing, 11th Author

Mrna Splicing Regulation Function Mammalian Cells Gene Expression Rna Processing Alternative Splicing Molecular Biology Biochemistry Cell Biology

Hua Zhou - Southern University of Science and Technology

Feng Ying - University of Chinese Academy of Sciences

Han Xiao - University of Chinese Academy of Sciences

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