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Xin-Tian Hu
Life Science
University of Chinese Academy of Sciences
Yunnan
Language: English, Chinese
Central Nervous System
Disease Models
Rhesus Monkeys
Mechanism Research
Neural Circuits
Cognitive Functions
Light
Health
Neuroscience
Biomedical Research
Areas of Focus
- Establishment and Mechanism Research of Central Nervous System Disease Models in Rhesus Monkeys
- Research on Neural Circuits Related to Cognitive Functions in Rhesus Monkeys
- Light and Health
Work Experience
- 2015-01~Present - Chinese Academy of Sciences Brain Excellence Center - Core Member
- 2005-12~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Researcher
- 2000-09~2005-12 - Baylor College of Medicine, USA - Postdoctoral Researcher
- 1994-09~2000-08 - Princeton University, USA - PhD
- 1991-07~1994-08 - Kunming Institute of Zoology, Chinese Academy of Sciences - Research Intern
- 1988-07~1991-07 - Kunming Institute of Zoology, Chinese Academy of Sciences - Master's Degree
- 1984-09~1988-06 - University of Science and Technology of China - Bachelor's Degree
Academic Background & Achievements
- 1994-09--2000-08 PhD: Princeton University, USA
- 1988-07--1991-07 Master's Degree: Kunming Institute of Zoology, Chinese Academy of Sciences
- 1984-09--1988-06 Bachelor's Degree: University of Science and Technology of China
Publications
- Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021
- Depletion of giant ANK2 in monkeys causes drastic brain volume loss, 14th Author, 2021
- Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021
- Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease, 3rd Author, 2021
- In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates, 10th Author, 2020
- 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates (vol 20, 258, 2019), 9th Author, 2020
- CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis, 11th Author, 2020
- Chronic Glucocorticoid Exposure Induces Depression-Like Phenotype in Rhesus Macaque (Macaca Mulatta), 11th Author, 2019
- 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates, 9th Author, 2019
- Behavioral screening tools for identifying autism in macaques: existing and promising tests, 4th Author, 2019
- Direct sunlight exposure reduces hair cortisol levels in rhesus monkeys (Macaca mulatta), 9th Author, 2019
- Alterations of Gray Matter Volume and White Matter Integrity in Maternal Deprivation Monkeys, 11th Author, 2018
- Phosphorylated alpha-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP, 11th Author, 2018
- Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging, 9th Author, 2018
- Alzheimer's Disease-like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates, 13th Author, 2018
- Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells, 10th Author, 2017
- Sr 2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses, 6th Author, 2017
- Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017
- Iron oxide nanoclusters for T-1 magnetic resonance imaging of non-human primates, 13th Author, 2017
- Kisspeptin-10 treatment generated specific GnRH expression in cells differentiated from rhesus monkey derived Lyon NSCs, 2nd Author, 2017
- comparativestudyofthetransfectionefficiencyofcommonlyusedviralvectorsinrhesusmonkeymacacamulattabrains, 13th Author, 2017
- The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria, 10th Author, 2017
- Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017
- Nonhuman Primates: Important Animal Models for Regenerative Medicine, 1st Author, 2012
Awards
- Core Researcher of the Chinese Academy of Sciences (2022): Institute Level
- Yunnan Province Overseas High-Level Talent Introduction (2011): Provincial Level
- Outstanding Professional and Technical Talent Award with Outstanding Contributions in Yunnan Province (2008): Third Prize, Provincial Level
- Chinese Academy of Sciences 'Introduction of Outstanding Overseas Talent' Title (2007): Institute Level
- Research on the Mechanism of Catecholamine Receptors in Working Memory of Rhesus Monkeys (2001): First Prize, Provincial Level
- NIH Postdoctoral Fellowship (2001): Institute Level
- Princeton University Department of Psychology Outstanding Teaching Assistant Award (1998): Institute Level
