Professor | Xin-Tian Hu | Asia Growth Partners

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Name	Xin-Tian Hu
Contact Information	xthu@mail.kiz.ac.cn
Language ability	English, Chinese
Province	Yunnan

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Name

Xin-Tian Hu

Contact Information

xthu@mail.kiz.ac.cn

Language ability

English, Chinese

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1994-09--2000-08 PhD: Princeton University, USA 1988-07--1991-07 Master's Degree: Kunming Institute of Zoology, Chinese Academy of Sciences 1984-09--1988-06 Bachelor's Degree: University of Science and Technology of China
Work Experience	2015-01~Present - Chinese Academy of Sciences Brain Excellence Center - Core Member 2005-12~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Researcher 2000-09~2005-12 - Baylor College of Medicine, USA - Postdoctoral Researcher 1994-09~2000-08 - Princeton University, USA - PhD 1991-07~1994-08 - Kunming Institute of Zoology, Chinese Academy of Sciences - Research Intern 1988-07~1991-07 - Kunming Institute of Zoology, Chinese Academy of Sciences - Master's Degree 1984-09~1988-06 - University of Science and Technology of China - Bachelor's Degree
Awards	Core Researcher of the Chinese Academy of Sciences (2022): Institute Level Yunnan Province Overseas High-Level Talent Introduction (2011): Provincial Level Outstanding Professional and Technical Talent Award with Outstanding Contributions in Yunnan Province (2008): Third Prize, Provincial Level Chinese Academy of Sciences 'Introduction of Outstanding Overseas Talent' Title (2007): Institute Level Research on the Mechanism of Catecholamine Receptors in Working Memory of Rhesus Monkeys (2001): First Prize, Provincial Level NIH Postdoctoral Fellowship (2001): Institute Level Princeton University Department of Psychology Outstanding Teaching Assistant Award (1998): Institute Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1994-09--2000-08 PhD: Princeton University, USA
1988-07--1991-07 Master's Degree: Kunming Institute of Zoology, Chinese Academy of Sciences
1984-09--1988-06 Bachelor's Degree: University of Science and Technology of China

Work Experience

2015-01~Present - Chinese Academy of Sciences Brain Excellence Center - Core Member
2005-12~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Researcher
2000-09~2005-12 - Baylor College of Medicine, USA - Postdoctoral Researcher
1994-09~2000-08 - Princeton University, USA - PhD
1991-07~1994-08 - Kunming Institute of Zoology, Chinese Academy of Sciences - Research Intern
1988-07~1991-07 - Kunming Institute of Zoology, Chinese Academy of Sciences - Master's Degree
1984-09~1988-06 - University of Science and Technology of China - Bachelor's Degree

Awards

Core Researcher of the Chinese Academy of Sciences (2022): Institute Level
Yunnan Province Overseas High-Level Talent Introduction (2011): Provincial Level
Outstanding Professional and Technical Talent Award with Outstanding Contributions in Yunnan Province (2008): Third Prize, Provincial Level
Chinese Academy of Sciences 'Introduction of Outstanding Overseas Talent' Title (2007): Institute Level
Research on the Mechanism of Catecholamine Receptors in Working Memory of Rhesus Monkeys (2001): First Prize, Provincial Level
NIH Postdoctoral Fellowship (2001): Institute Level
Princeton University Department of Psychology Outstanding Teaching Assistant Award (1998): Institute Level

Areas of Focus	Establishment and Mechanism Research of Central Nervous System Disease Models in Rhesus Monkeys Research on Neural Circuits Related to Cognitive Functions in Rhesus Monkeys Light and Health
Publications	Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021 Depletion of giant ANK2 in monkeys causes drastic brain volume loss, 14th Author, 2021 Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021 Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease, 3rd Author, 2021 In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates, 10th Author, 2020 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates (vol 20, 258, 2019), 9th Author, 2020 CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis, 11th Author, 2020 Chronic Glucocorticoid Exposure Induces Depression-Like Phenotype in Rhesus Macaque (Macaca Mulatta), 11th Author, 2019 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates, 9th Author, 2019 Behavioral screening tools for identifying autism in macaques: existing and promising tests, 4th Author, 2019 Direct sunlight exposure reduces hair cortisol levels in rhesus monkeys (Macaca mulatta), 9th Author, 2019 Alterations of Gray Matter Volume and White Matter Integrity in Maternal Deprivation Monkeys, 11th Author, 2018 Phosphorylated alpha-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP, 11th Author, 2018 Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging, 9th Author, 2018 Alzheimer's Disease-like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates, 13th Author, 2018 Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells, 10th Author, 2017 Sr 2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses, 6th Author, 2017 Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017 Iron oxide nanoclusters for T-1 magnetic resonance imaging of non-human primates, 13th Author, 2017 Kisspeptin-10 treatment generated specific GnRH expression in cells differentiated from rhesus monkey derived Lyon NSCs, 2nd Author, 2017 comparativestudyofthetransfectionefficiencyofcommonlyusedviralvectorsinrhesusmonkeymacacamulattabrains, 13th Author, 2017 The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria, 10th Author, 2017 Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017 Nonhuman Primates: Important Animal Models for Regenerative Medicine, 1st Author, 2012

Areas of Focus

Establishment and Mechanism Research of Central Nervous System Disease Models in Rhesus Monkeys
Research on Neural Circuits Related to Cognitive Functions in Rhesus Monkeys
Light and Health

Publications

Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021
Depletion of giant ANK2 in monkeys causes drastic brain volume loss, 14th Author, 2021
Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 17th Author, 2021
Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease, 3rd Author, 2021
In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates, 10th Author, 2020
547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates (vol 20, 258, 2019), 9th Author, 2020
CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis, 11th Author, 2020
Chronic Glucocorticoid Exposure Induces Depression-Like Phenotype in Rhesus Macaque (Macaca Mulatta), 11th Author, 2019
547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates, 9th Author, 2019
Behavioral screening tools for identifying autism in macaques: existing and promising tests, 4th Author, 2019
Direct sunlight exposure reduces hair cortisol levels in rhesus monkeys (Macaca mulatta), 9th Author, 2019
Alterations of Gray Matter Volume and White Matter Integrity in Maternal Deprivation Monkeys, 11th Author, 2018
Phosphorylated alpha-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP, 11th Author, 2018
Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging, 9th Author, 2018
Alzheimer's Disease-like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates, 13th Author, 2018
Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells, 10th Author, 2017
Sr 2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses, 6th Author, 2017
Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017
Iron oxide nanoclusters for T-1 magnetic resonance imaging of non-human primates, 13th Author, 2017
Kisspeptin-10 treatment generated specific GnRH expression in cells differentiated from rhesus monkey derived Lyon NSCs, 2nd Author, 2017
comparativestudyofthetransfectionefficiencyofcommonlyusedviralvectorsinrhesusmonkeymacacamulattabrains, 13th Author, 2017
The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria, 10th Author, 2017
Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, 34th Author, 2017
Nonhuman Primates: Important Animal Models for Regenerative Medicine, 1st Author, 2012

Central Nervous System Disease Models Rhesus Monkeys Mechanism Research Neural Circuits Cognitive Functions Light Health Neuroscience Biomedical Research

Ma Ji - East China Normal University

Fan Yang - University of Chinese Academy of Sciences

Yuhua Fu - Fudan University

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