Professor | Yuhua Fu | Asia Growth Partners

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Name

Yuhua Fu

Contact Information

fuyuhua@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	2015 - PhD: Fudan University, Institute of Biomedical Sciences 2015-2017 - Postdoctoral Training: Fudan University, Institute of Brain Science
Work Experience	2015-2017 - Postdoctoral Researcher - Fudan University, Institute of Brain Science 2017-Present - Associate Researcher - Fudan University, School of Life Sciences
Awards	Yangtze River Delta Young Neuroscientist Award (2020) Sanofi-Cell Research Annual Outstanding Paper Award (2022)

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

2015-2017 - Postdoctoral Researcher - Fudan University, Institute of Brain Science
2017-Present - Associate Researcher - Fudan University, School of Life Sciences

Awards

Areas of Focus	Mechanisms and applications of autophagy and lipophagy Mechanisms and interventions of polyglutamine (polyQ) and polyglycine (polyG) diseases
Publications	Autophagic Clearance of Lipid Droplets Alters Metabolic Phenotypes in a Genetic Obesity–Diabetes Mouse Model, Ningxie Chen; Boxun Lu; Yuhua Fu, 2022 Degradation of lipid droplets by chimeric autophagy-tethering compounds, Fu, Yuhua; Chen, Ningxie; Wang, Ziying; Luo, Shouqing; Ding, Yu; Lu, Boxun, 2021 Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy, Xiaodan Zhang; Xue Wen; Ismael Al-Ramahi; Juan Botas; Boxun Lu; Yuhua Fu, 2021 Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex, Xiao-jing Li#; Yuan-yuan Zhang#; Yu-hua Fu#; Hao Zhang; He-xuan Li; Quan-fu Li; Hai-ling Li; Ren-ke Tan; Chen-xiao Jiang; Wei Jiang; Zeng-xia Li; Cheng Luo; Bo-xun Lu; Yong-jun Dang, 2021 A toxic mutant huntingtin species is resistant to selective autophagy, Yuhua Fu#; Peng Wu#; Yuyin Pan#; Xiaoli Sun#; Huiya Yang; Marian Difiglia; Boxun Lu, 2017 Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models, Meng Yu#; Yuhua Fu#; Yijiang Liang#; Haikun Song; Yao Yao; Peng Wu; Yuwei Yao; Yuyin Pan; Lixiang Ma; Saiyin Hexige; Yu Ding; Shouqing Luo; Boxun Lu, 2017

Areas of Focus

Mechanisms and applications of autophagy and lipophagy
Mechanisms and interventions of polyglutamine (polyQ) and polyglycine (polyG) diseases

Publications

Autophagic Clearance of Lipid Droplets Alters Metabolic Phenotypes in a Genetic Obesity–Diabetes Mouse Model, Ningxie Chen; Boxun Lu*; Yuhua Fu*, 2022
Degradation of lipid droplets by chimeric autophagy-tethering compounds, Fu, Yuhua; Chen, Ningxie; Wang, Ziying; Luo, Shouqing; Ding, Yu; Lu, Boxun, 2021
Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy, Xiaodan Zhang; Xue Wen; Ismael Al-Ramahi; Juan Botas; Boxun Lu; Yuhua Fu, 2021
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex, Xiao-jing Li#; Yuan-yuan Zhang#; Yu-hua Fu#; Hao Zhang; He-xuan Li; Quan-fu Li; Hai-ling Li; Ren-ke Tan; Chen-xiao Jiang; Wei Jiang; Zeng-xia Li; Cheng Luo; Bo-xun Lu; Yong-jun Dang, 2021
A toxic mutant huntingtin species is resistant to selective autophagy, Yuhua Fu#; Peng Wu#; Yuyin Pan#; Xiaoli Sun#; Huiya Yang; Marian Difiglia; Boxun Lu, 2017
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models, Meng Yu#; Yuhua Fu#; Yijiang Liang#; Haikun Song; Yao Yao; Peng Wu; Yuwei Yao; Yuyin Pan; Lixiang Ma; Saiyin Hexige; Yu Ding; Shouqing Luo; Boxun Lu, 2017

Autophagy Lipophagy Polyglutamine Polyglycine Disease Mechanisms Interventions Neuroscience Cell Biology Biomedical Research Metabolic Phenotypes

Xie Zhiping - Shanghai Jiao Tong University

Jiali Wei - Shanghai University

Liang Ge - Tsinghua University

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