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Yuhua Fu
Life Science
Fudan University
Shanghai
Language: Chinese, English
Autophagy
Lipophagy
Polyglutamine
Polyglycine
Disease Mechanisms
Interventions
Neuroscience
Cell Biology
Biomedical Research
Metabolic Phenotypes
Areas of Focus
- Mechanisms and applications of autophagy and lipophagy
- Mechanisms and interventions of polyglutamine (polyQ) and polyglycine (polyG) diseases
Work Experience
- 2015-2017 - Postdoctoral Researcher - Fudan University, Institute of Brain Science
- 2017-Present - Associate Researcher - Fudan University, School of Life Sciences
Academic Background & Achievements
- 2015 - PhD: Fudan University, Institute of Biomedical Sciences
- 2015-2017 - Postdoctoral Training: Fudan University, Institute of Brain Science
Publications
- Autophagic Clearance of Lipid Droplets Alters Metabolic Phenotypes in a Genetic Obesity–Diabetes Mouse Model, Ningxie Chen; Boxun Lu*; Yuhua Fu*, 2022
- Degradation of lipid droplets by chimeric autophagy-tethering compounds, Fu, Yuhua; Chen, Ningxie; Wang, Ziying; Luo, Shouqing; Ding, Yu; Lu, Boxun, 2021
- Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy, Xiaodan Zhang; Xue Wen; Ismael Al-Ramahi; Juan Botas; Boxun Lu; Yuhua Fu, 2021
- Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex, Xiao-jing Li#; Yuan-yuan Zhang#; Yu-hua Fu#; Hao Zhang; He-xuan Li; Quan-fu Li; Hai-ling Li; Ren-ke Tan; Chen-xiao Jiang; Wei Jiang; Zeng-xia Li; Cheng Luo; Bo-xun Lu; Yong-jun Dang, 2021
- A toxic mutant huntingtin species is resistant to selective autophagy, Yuhua Fu#; Peng Wu#; Yuyin Pan#; Xiaoli Sun#; Huiya Yang; Marian Difiglia; Boxun Lu, 2017
- Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models, Meng Yu#; Yuhua Fu#; Yijiang Liang#; Haikun Song; Yao Yao; Peng Wu; Yuwei Yao; Yuyin Pan; Lixiang Ma; Saiyin Hexige; Yu Ding; Shouqing Luo; Boxun Lu, 2017
Awards
- Yangtze River Delta Young Neuroscientist Award (2020)
- Sanofi-Cell Research Annual Outstanding Paper Award (2022)
