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Hanhua Hu
Life Science
University of Chinese Academy of Sciences
Hubei
Language: Chinese, English
Algal Synthetic Biology: Algae
Synthetic Biology
Genetic Engineering
Biofuels
Metabolic Pathways
Photosynthesis
Carbon Fixation
Biotechnology
Microalgae
Crispr
Diatom Biology: Diatoms
Marine Biology
Silica
Areas of Focus
- Algal Synthetic Biology
- Diatom Biology
Work Experience
- 2008-01~2010-01 - École Normale Supérieure, Paris - Visiting Scholar/Postdoctoral Researcher
- 2004-04~Present - Institute of Hydrobiology, Chinese Academy of Sciences - Associate Researcher/Researcher
- 2002-01~2004-03 - Institute of Process Engineering, Chinese Academy of Sciences - Postdoctoral Researcher
- 2001-08~2004-02 - Xiamen University - Lecturer
Academic Background & Achievements
- 1996-09--2001-07 PhD in Science: Institute of Hydrobiology, Chinese Academy of Sciences
Publications
- A key gene, violaxanthin de-epoxidase-like 1, enhances fucoxanthin accumulation in Phaeodactylum tricornutum, Chenjie Li, Yufang Pan, Wenxiu Yin, Jin Liu, Hanhua Hu, 2024
- Zeaxanthin epoxidase is involved in the carotenoid biosynthesis and light-dependent growth of the marine alga Nannochloropsis oceanica, Meijing Liu, Wei Ding, Yufang Pan, Hanhua Hu, Jin Liu, 2023
- CRISPR/Cas9-Mediated Genome Editing via Homologous Recombination in a Centric Diatom Chaetoceros muelleri, Yin, Wenxiu, Hu, Hanhua, 2023
- NmrA acts as a positive regulator of nitrate assimilation in Phaeodactylum tricornutum, Chen Yu, Yufang Pan, Hanhua Hu, 2023
- 利用饵料微藻表达抗菌肽及其初步应用, 潘玉芳, 杨欢, 陈怡雯, 韩冬, 胡晗华, 2023
- Pyruvate orthophosphate dikinase is required for the acclimation to high bicarbonate concentrations in Phaeodactylum tricornutum, Teng Huang, Fan Hu, Yufang Pan, Chenjie Li, Hanhua Hu, 2023
- CGI-58 Protein Acts as a Positive Regulator of Triacylglycerol Accumulation in Phaeodactylum tricornutum, Qin Shu, Yufang Pan, Hanhua Hu, 2023
- Editorial: Metabolic Regulation of Diatoms and Other Chromalveolates, Marchand, Justine, Hu, Hanhua, Manoylov, Kalina, Schoefs, Benoit, 2022
- The Transition Toward Nitrogen Deprivation in Diatoms Requires Chloroplast Stand-By and Deep Metabolic Reshuffling, Scarsini, Matteo, ThirietRupert, Stanislas, Veidl, Brigitte, Mondeguer, Florence, Hu, Hanhua, Marchand, Justine, Schoefs, Benoit, 2022
- Multiplexed CRISPR/Cas9 editing of the long-chain acyl-CoA synthetase family in the diatom Phaeodactylum tricornutum reveals that mitochondrial ptACSL3 is involved in the synthesis of storage lipids, Hao, Xiahui, Chen, Wenchao, Amato, Alberto, Jouhet, Juliette, Marechal, Eric, Moog, Daniel, Hu, Hanhua, Jin, Hu, You, Lingjie, Huang, Fenghong, Moosburner, Mark, Allen, Andrew E, Gong, Yangmin, 2022
- PDAT regulates PE as transient carbon sink alternative to triacylglycerol in Nannochloropsis, Yang, Juan, Liu, Jin, Pan, Yufang, Marechal, Eric, Amato, Alberto, Liu, Meijing, Gong, Yangmin, Li, Yantao, Hu, Hanhua, 2022
- Metabolic engineering of the oleaginous alga Nannochloropsis for enriching eicosapentaenoic acid in triacylglycerol by combined pulling and pushing strategies, Liu, Jin, Liu, Meijing, Pan, Yufang, Shi, Ying, Hu, Hanhua, 2022
- Impaired photoprotection in Phaeodactylum tricornutum KEA3 mutants reveals the proton regulatory circuit of diatoms light acclimation, Seydoux, Claire, Storti, Mattia, Giovagnetti, Vasco, Matuszynska, Anna, Guglielmino, Erika, Zhao, Xue, Giustini, Cecile, Pan, Yufang, Blommaert, Lander, Angulo, Jhoanell, Ruban, Alexander, V, Hu, Hanhua, Bailleul, Benjamin, Courtois, Florence, Allorent, Guillaume, Finazzi, Giovanni, 2022
- Lipid production is more than doubled by manipulating a diacylglycerol acyltransferase in algae, Zhang, Yu, Pan, Yufang, Ding, Wei, Hu, Hanhua, Liu, Jin, 2021
- High-efficiency transformation of a centric diatom Chaetoceros muelleri by electroporation with a variety of selectable markers, Yin, Wenxiu, Hu, Hanhua, 2021
- ∆6 fatty acid elongase is involved in eicosapentaenoic acid biosynthesis via the ω6 pathway in the marine alga Nannochloropsis oceanica, Shi, Ying, Liu, Meijing, Pan, Yufang, Hu, Hanhua, Liu, Jin, 2021
- Amino Acid Catabolism During Nitrogen Limitation in Phaeodactylum tricornutum, Pan, Yufang, Hu, Fan, Yu, Chen, Li, Chenjie, Huang, Teng, Hu, Hanhua, 2020
- Screening of High Temperature-Tolerant Oleaginous Diatoms, Zhang, Lingxiang, Hu, Fan, Wan, Xiu, Pan, Yufang, Hu, Hanhua, 2020
- Screening High CO2-Tolerant Oleaginous Microalgae from Genera Desmodesmus and Scenedesmus, Yang, Juan, Zhang, Chunye, Hu, Hanhua, 2020
- A genomics approach reveals the global genetic polymorphism, structure, and functional diversity of ten accessions of the marine model diatom Phaeodactylum tricornutum, Achal Rastogi, Fabio Rocha Jimenez Vieira, AnneFlore DetonCabanillas, Alaguraj Veluchamy, Catherine Cantrel, Gaohong Wang, Pieter Vanormelingen, Chris Bowler, Gwenael Piganeau, Hanhua Hu, Leila Tirichine, 2020
- High efficiency transformation by electroporation of the freshwater alga Nannochloropsis limnetica, Chen, Yiwen, Hu, Hanhua, 2019
- Knockdown of carbonate anhydrase elevates Nannochloropsis productivity at high CO2 level, Wei, Li, Shen, Chen, El Hajjami, Mohamed, You, Wuxin, Wang, Qintao, Zhang, Peng, Ji, Yuetong, Hu, Hanhua, Hu, Qiang, Poetsch, Ansgar, Xu, Jian, 2019
- Enhanced triacylglycerol production in the diatom Phaeodactylum tricornutum by inactivation of a Hotdog-fold thioesterase gene using TALEN-based targeted mutagenesis, Hao, Xiahui, Luo, Ling, Jouhet, Juliette, Rebeille, Fabrice, Marechal, Eric, Hu, Hanhua, Pan, Yufang, Tan, Xiaoming, Chen, Zhuo, You, Lingjie, Chen, Hong, Wei, Fang, Gong, Yangmin, 2018
- Acetylome Profiling Reveals Extensive Lysine Acetylation of the Fatty Acid Metabolism Pathway in the Diatom Phaeodactylum tricornutum, Chen, Zhuo, Luo, Ling, Chen, Runfa, Hu, Hanhua, Pan, Yufang, Jiang, Haibo, Wan, Xia, Jin, Hu, Gong, Yangmin, 2018
- Identification of the triacylglycerol lipase in the chloroplast envelope of the diatom Phaeodactylum tricornutum, Li, Xiaolong, Pan, Yufang, Hu, Hanhua, 2018
- 湖泊微拟球藻高含油突变株的构建及筛选, 张玲香, 陈怡雯, 胡晗华, 2018
- Producing Designer Oils in Industrial Microalgae by Rational Modulation of Co-evolving Type-2 Diacylglycerol Acyltransferases, Xin, Yi, Lu, Yandu, Lee, YiYing, Wei, Li, Jia, Jing, Wang, Qintao, Wang, Dongmei, Bai, Fali, Hu, Hanhua, Hu, Qiang, Liu, Jin, Li, Yantao, Xu, Jian, 2017
- The peculiar carbon metabolism in diatoms, Schoefs, Benoit, Hu, Hanhua, Kroth, Peter G, 2017
- RNAi-based targeted gene knockdown in the model oleaginous microalgae Nannochloropsis oceanica, Wei, Li, Xin, Yi, Wang, Qintao, Yang, Juan, Hu, Hanhua, Xu, Jian, 2017
- A type-I diacylglycerol acyltransferase modulates triacylglycerol biosynthesis and fatty acid composition in the oleaginous microalga, Nannochloropsis oceanica, Wei, Hehong, Shi, Ying, Ma, Xiaonian, Pan, Yufang, Hu, Hanhua, Li, Yantao, Luo, Ming, Gerken, Henri, Liu, Jin, 2017
- 3-Hydroxyisobutyryl-CoA hydrolase involved in isoleucine catabolism regulates triacylglycerol accumulation in Phaeodactylum tricornutum, Pan, Yufang, Yang, Juan, Gong, Yangmin, Li, Xiaolong, Hu, Hanhua, 2017
- Knockdown of phosphoenolpyruvate carboxykinase increases carbon flux to lipid synthesis in Phaeodactylum tricornutum, Yang, Juan, Pan, Yufang, Bowler, Chris, Zhang, Lingxiang, Hu, Hanhua, 2016
- 不同氮源及CO2浓度下湖泊微拟球藻的生长及产油特性分析, 李凤娟, 万秀, 方仙桃, 胡锐, 高大文, 胡晗华, 2015
- 微藻高CO_2
