Areas of Focus
- Artificial synthesis pathways
- Microbial cell factory tolerance modification
Work Experience
- 2019 - Present - Group Leader and PhD Supervisor, National Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University
Academic Background & Achievements
- 2008 Bachelor of Bioengineering, Shandong Agricultural University
- 2011 Master of Microbiology, Shandong University, National Key Laboratory of Microbial Technology
- 2014 PhD in Microbiology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
- Postdoctoral research in Chemical and Biological Engineering, Iowa State University, USA (2014-2016)
- Postdoctoral research in Chemistry and Biomolecular Systems and Biosciences, Rice University, USA (2016-2019)
Publications
- A non-carboxylative route for the efficient synthesis of central metabolite malonyl-CoA and its derived products, Zai Gao Tan, 2023
- Integration of (S)-2,3-oxidosqualene enables E. coli to become Iron Man E. coli with improved overall tolerance, Zai Gao Tan, 2023
- Designing artificial pathways for improving chemical production, Zai Gao Tan, 2023
- A polyketoacyl-CoA thiolase-dependent pathway for the synthesis of polyketide backbones, Zai Gao Tan, 2023
- The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis, Zai Gao Tan, 2023
- Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production, Zai Gao Tan, 2023
- Synthetic Pathway for the Production of Olivetolic Acid in Escherichia coli, Zai Gao Tan, 2023
- Engineering Escherichia coli Membrane Phospholipid Head Distribution Improves Tolerance and Production of Biorenewables, Zai Gao Tan, 2023
- Improving Escherichia coli membrane integrity and fatty acid production by expression tuning of FadL and OmpF, Zai Gao Tan, 2023
- Membrane Engineering via Trans Unsaturated Fatty Acids Production Improves Escherichia coli Robustness and Production of Biorenewables, Zai Gao Tan, 2023
