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Shuangying Jiang
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Synthetic Genomics: Gene Synthesis
Genome Editing
Synthetic Biology
Dna Assembly
Genetic Circuits
Metabolic Engineering
Synthetic Organisms
Genome Design
Synthetic Chromosomes
Gene Regulation
Epigenetics: Dna Methylation
Histone Modification
Chromatin Remodeling
Gene Expression
Non-Coding Rna
Epigenetic Inheritance
Epigenetic Therapy
Chromatin Structure
Transcriptional Regulation
Epigenetic Markers
Areas of Focus
- Synthetic Genomics
- Epigenetics
Work Experience
- 2020-01 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2019-07 to 2020-01 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher
- 2017-08 to 2019-07 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Postdoctoral Researcher
Academic Background & Achievements
- 2011-09 to 2017-06 PhD: Tsinghua University
- 2007-09 to 2011-06 Bachelor's: Northeast Agricultural University
Publications
- High plasticity of ribosomal DNA organization in budding yeast, Shuangying Jiang, Zelin Cai, Yun Wang, Cheng Zeng, Jiaying Zhang, Wenfei Yu, Chenghao Su, Shijun Zhao, Ying Chen, Yue Shen, Yingxin Ma, Yizhi Cai, Junbiao Dai, 2024
- Building a eukaryotic chromosome arm by de novo design and synthesis, Shuangying Jiang, Zhouqing Luo, Jie Wu, Kang Yu, Shijun Zhao, Zelin Cai, Wenfei Yu, Hui Wang, Li Cheng, Zhenzhen Liang, Hui Gao, Marco Monti, Daniel Schindler, Linsen Huang, Cheng Zeng, Weimin Zhang, Chun Zhou, Yuanwei Tang, Tianyi Li, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Qiao Zhao, Junbiao Dai, 2023
- Design, construction, and functional characterization of a tRNA neochromosome in yeast, Daniel Schindler, Roy SK Walker, Shuangying Jiang, Aaron N Brooks, Yun Wang, Carolin A Mller, Charlotte Cockram, Yisha Luo, Alicia Garca, Daniel Schraivogel, Julien Mozziconacci, Noah Pena, Mahdi Assari, Mara del Carmen Snchez Olmos, Yu Zhao, Alba Ballerini, Benjamin A Blount, Jitong Cai, Lois Ogunlana, Wei Liu, Katarina Jnsson, Dariusz Abramczyk, Eva GarciaRuiz, Tomasz W Turowski, Reem Swidah, Tom Ellis, Tao Pan, Francisco Antequera, Yue Shen, Conrad A Nieduszynski, Romain Koszul, Junbiao Dai, Lars M Steinmetz, Jef D Boeke, Yizhi Cai, 2023
- Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast, Yue Shen, Feng Gao, Yun Wang, Yuerong Wang, Ju Zheng, Jianhui Gong, Jintao Zhang, Zhouqing Luo, Daniel Schindler, Yang Deng, Weichao Ding, Tao Lin, Reem Swidah, Hongcui Zhao, Shuangying Jiang, Cheng Zeng, Shihong Chen, Tai Chen, Yong Wang, Yisha Luo, Leslie Mitchell, Joel S Bader, Guojie Zhang, Xia Shen, Jian Wang, Xian Fu, Junbiao Dai, Jef D Boeke, Huanming Yang, Xun Xu, Yizhi Cai, 2023
- Engineering and functional analysis of yeast with a monotypic 40S ribosome subunit, Hu, Xin, Jiang, Shuangying, Xu, Feifei, Zeng, Cheng, Wang, Xiangxiang, Liu, Wei, Cheng, Aimin, Ma, Chengying, Gao, Ning, Zhao, Yuyu, Dai, Junbiao, Zhao, Guanghou, 2022
- Efficient de novo assembly and modification of large DNA fragments, Jiang, Shuangying, Tang, Yuanwei, Xiang, Liang, Zhu, Xinlu, Cai, Zelin, Li, Ling, Chen, Yingxi, Chen, Peishuang, Feng, Yuge, Lin, Xin, Li, Guoqiang, Sharif, Jafar, Dai, Junbiao, 2022
- Compacting a synthetic yeast chromosome arm, Luo, Zhouqing, Yu, Kang, Xie, Shangqian, Monti, Marco, Schindler, Daniel, Fang, Yuan, Zhao, Shijun, Liang, Zhenzhen, Jiang, Shuangying, Luan, Meiwei, Xiao, Chuanle, Cai, Yizhi, Dai, Junbiao, 2021
- Sc3.0: revamping and minimizing the yeast genome, Dai, Junbiao, Boeke, Jef D, Luo, Zhouqing, Jiang, Shuangying, Cai, Yizhi, 2020
- Whole-Genome Regulation for Yeast Metabolic Engineering, Jiang, Shuangying, Si, Tong, Dai, Junbiao, 2020
- Probing eukaryotic genome functions with synthetic chromosomes, Luo, Zhouqing, Hoffmann, Stefan A, Jiang, Shuangying, Cai, Yizhi, Dai, Junbiao, 2020
- Genetic interaction mapping informs integrative structure determination of protein complexes, Braberg, Hannes, Echeverria, Ignacia, Bohn, Stefan, Cimermancic, Peter, Shiver, Anthony, Alexander, Richard, Xu, Jiewei, Shales, Michael, Dronamraju, Raghuvar, Jiang, Shuangying, Dwivedi, Gajendradhar, Bogdanoff, Derek, Chaung, Kaitlin K, Huttenhain, Ruth, Wang, Shuyi, Mavor, David, Pellarin, Riccardo, Schneidman, Dina, Bader, Joel S, Fraser, James S, Morris, John, Haber, James E, Strahl, Brian D, Gross, Carol A, Dai, Junbiao, Boeke, Jef D, Sali, Andrej, Krogan, Nevan J, 2020
- Synthetic yeast genomes for studying chromosomal features, Shuangying Jiang, Shijun Zhao, Zelin Cai, Yuanwei Tang, Junbiao Dai, 2020
- Inevitability or contingency: how many chromosomes do we really need?, Jiang, Shuangying, Dai, Junbiao, 2019
- Multiplex Genome Engineering for Optimizing Bioproduction in Saccharomyces cerevisiae, Auxillos, Jamie Y, GarciaRuiz, Eva, Jones, Sally, Li, Tianyi, Jiang, Shuangying, Dai, Junbiao, Cai, Yizhi, 2019
- Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks, Cheng, Li, Liu, Chengxi, Jiang, Shuangying, Hou, Sha, Huang, Jinguo, Chen, Ziqing, Sun, Yangyang, Qi, Huan, Jiang, Hewei, Wang, Jingfang, Zhou, Yiming, Czajkowsky, Daniel M, Dai, Junbiao, Tao, Shengce, 2018
- Whole genome engineering by synthesis, Luo, Zhouqing, Yang, Qing, Geng, Binan, Jiang, Shuangying, Yang, Shihui, Li, Xiaozheng, Cai, Yizhi, Dai, Junbiao, 2018
- Engineering the ribosomal DNA in a megabase synthetic chromosome, Zhang, Weimin, Zhao, Guanghou, Luo, Zhouqing, Lin, Yicong, Wang, Lihui, Guo, Yakun, Wang, Ann, Jiang, Shuangying, Jiang, Qingwen, Gong, Jianhui, Wang, Yun, Hou, Sha, Huang, Jing, Li, Tianyi, Qin, Yiran, Dong, Junkai, Qin, Qin, Zhang, Jiaying, Zou, Xinzhi, He, Xi, Zhao, Li, Xiao, Yibo, Xu, Meng, Cheng, Erchao, Huang, Ning, Zhou, Tong, Shen, Yue, Walker, Roy, Luo, Yisha, Kuang, Zheng, Mitchell, Leslie A, Yang, Kun, Richardson, Sarah M, Wu, Yi, Li, BingZhi, Yuan, YingJin, Yang, Huanming, Lin, Jiwei, Chen, GuoQiang, Wu, Qingyu, Bader, Joel S, Cai, Yizhi, Boeke, Jef D, Dai, Junbiao, 2017
- Dissecting Nucleosome Function with a Comprehensive Histone H2A and H2B Mutant Library, Jiang, Shuangying, Liu, Yan, Xu, Caiyue, Wang, Yun, Gong, Jianhui, Shen, Yue, Wu, Qingyu, Boeke, Jef D, Dai, Junbiao, 2017
- Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae, Jiang, Shuangying, Liu, Yan, Wang, Ann, Qin, Yiran, Luo, Maoguo, Wu, Qingyu, Boeke, Jef D, Dai, Junbiao, 2017
- Kinetochore Function and Chromosome Segregation Rely on Critical Residues in Histones H3 and H4 in Budding Yeast, Ng, Tessie M, Lenstra, Tineke L, Duggan, Nicole, Jiang, Shuangying, Ceto, Steven, Holstege, Frank C P, Dai, Junbiao, Boeke, Jef D, Biggins, Sue, 2013
