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Jiaquan Liu
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Fluorescence
Imaging
Single-Molecule
Rna
Metabolism
Transcription
Regulation
Innate
Immunity
Biochemistry
Areas of Focus
- Single-molecule fluorescence imaging
- RNA metabolism, transcription regulation, and related innate immunity
Work Experience
- 2017-09~2019-08 - Ohio State University - Research Assistant
- 2012-09~2017-09 - Ohio State University - Postdoctoral Researcher
- 2007-09~2012-06 - Wuhan University - PhD
- 2003-09~2007-06 - Wuhan University - Bachelor
Academic Background & Achievements
- 2007-09--2012-06 PhD: Wuhan University
- 2003-09--2007-06 Bachelor: Wuhan University
Publications
- MutS and MutL Sliding Clamps in DNA Mismatch Repair, Genome Instability & Disease, 2022
- Understanding lncRNA-protein assemblies with imaging and single-molecule approaches, CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022
- MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair, NATURE COMMUNICATIONS, 2022
- Observing Protein One-Dimensional Sliding: Methodology and Biological Significance, BIOMOLECULES, 2021
- lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription, SCIENCE, 2021
- MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair, NATURE COMMUNICATIONS, 2019
- Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, 2018
- MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018
- Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, 2016
- Widespread nuclease contamination in commonly used oxygen-scavenging systems, NATURE METHODS, 2015
- An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, 2015
- Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015
Awards
- USCACA-AFCR Scholar Award (2019): Other
- Pelotonia Postdoctoral Fellowship (2017): Research Institute (School)
