Professor | 刘珈泉 | 数字化转型顾问

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Name

刘珈泉

Contact Information

liujiaquan@sibcb.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2012-06 博士: 武汉大学 2003-09--2007-06 学士: 武汉大学
Work Experience	2017-09~2019-08 - 俄亥俄州立大学 - 研究助理 2012-09~2017-09 - 俄亥俄州立大学 - 博士后研究员 2007-09~2012-06 - 武汉大学 - 博士 2003-09~2007-06 - 武汉大学 - 学士
Awards	USCACA-AFCR Scholar Award (2019): 其他 Pelotonia Postdoctoral Fellowship (2017): 研究所（学校）

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	单分子荧光成像 RNA代谢、转录调控及相关天然免疫
Publications	MutS and MutL Sliding Clamps in DNA Mismatch Repair, Genome Instability & Disease, 2022 Understanding lncRNA-protein assemblies with imaging and single-molecule approaches, CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022 MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair, NATURE COMMUNICATIONS, 2022 Observing Protein One-Dimensional Sliding: Methodology and Biological Significance, BIOMOLECULES, 2021 lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription, SCIENCE, 2021 MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair, NATURE COMMUNICATIONS, 2019 Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, 2018 MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018 Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, 2016 Widespread nuclease contamination in commonly used oxygen-scavenging systems, NATURE METHODS, 2015 An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, 2015 Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015

Areas of Focus

单分子荧光成像
RNA代谢、转录调控及相关天然免疫

Publications

MutS and MutL Sliding Clamps in DNA Mismatch Repair, Genome Instability & Disease, 2022
Understanding lncRNA-protein assemblies with imaging and single-molecule approaches, CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022
MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair, NATURE COMMUNICATIONS, 2022
Observing Protein One-Dimensional Sliding: Methodology and Biological Significance, BIOMOLECULES, 2021
lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription, SCIENCE, 2021
MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair, NATURE COMMUNICATIONS, 2019
Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, 2018
MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018
Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, 2016
Widespread nuclease contamination in commonly used oxygen-scavenging systems, NATURE METHODS, 2015
An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, 2015
Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015

荧光成像单分子 Rna 代谢转录调控天然免疫生物化学

张云芳 - 同济大学

Area of Focus
表观遗传学 | 遗传 | Rna | 修饰 | 调控 | 父系 | 性状 | 机制 | 精子 | 胚胎

蔡汝洁 - 上海师范大学

Area of Focus
Rna | 结构 | 调控 | 非编码 | 机理 | 病毒 | 包装 | 致病 | 研究 | 科研

冯畅 - 上海大学

Area of Focus
生物标志物 | 癌症 | 检测 | 诊断 | Dna | Rna | 放大 | 分子生物学 | 生物化学 | 临床研究

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