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刘珈泉
Life Science
中国科学院大学
上海
Language: 中文, 英语
荧光
成像
单分子
Rna
代谢
转录
调控
天然
免疫
生物化学
Areas of Focus
- 单分子荧光成像
- RNA代谢、转录调控及相关天然免疫
Work Experience
- 2017-09~2019-08 - 俄亥俄州立大学 - 研究助理
- 2012-09~2017-09 - 俄亥俄州立大学 - 博士后研究员
- 2007-09~2012-06 - 武汉大学 - 博士
- 2003-09~2007-06 - 武汉大学 - 学士
Academic Background & Achievements
- 2007-09--2012-06 博士: 武汉大学
- 2003-09--2007-06 学士: 武汉大学
Publications
- MutS and MutL Sliding Clamps in DNA Mismatch Repair, Genome Instability & Disease, 2022
- Understanding lncRNA-protein assemblies with imaging and single-molecule approaches, CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022
- MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair, NATURE COMMUNICATIONS, 2022
- Observing Protein One-Dimensional Sliding: Methodology and Biological Significance, BIOMOLECULES, 2021
- lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription, SCIENCE, 2021
- MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair, NATURE COMMUNICATIONS, 2019
- Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, 2018
- MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018
- Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, 2016
- Widespread nuclease contamination in commonly used oxygen-scavenging systems, NATURE METHODS, 2015
- An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, 2015
- Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015
Awards
- USCACA-AFCR Scholar Award (2019): 其他
- Pelotonia Postdoctoral Fellowship (2017): 研究所（学校）
