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Shiwu Li
Life Science
University of Chinese Academy of Sciences
Yunnan
Language: Chinese, English
Mental Disorders
Animal Models
Schizophrenia
Depression
Bipolar Disorder
Neuroscience
Genetics
Brain Health
Hypoxia
High-Altitude
Areas of Focus
- Animal Models of Mental Disorders
- High-Altitude Hypoxia and Brain Health
Work Experience
- 2021-04 to Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
- 2021-01 to 2021-04 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
- 2015-09 to 2017-08 - Kunming Institute of Zoology, Chinese Academy of Sciences - Research Intern
Academic Background & Achievements
- 2017-09 to 2021-01 PhD: Kunming Institute of Zoology, Chinese Academy of Sciences
- 2012-09 to 2015-06 Master's: Kunming University of Science and Technology
- 2008-09 to 2012-06 Bachelor's: Xiangnan University
Publications
- Genomic landscape and functional characterization of structural variations in schizophrenia and bipolar disorder, Corresponding Author, 2024
- Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, 9th Author, 2023
- Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, 10th Author, 2023
- The schizophrenia-associated missense variant rs13107325 regulates dendritic spine density, 1st Author, 2022
- Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression, 1st Author, 2022
- Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1, 2nd Author, 2022
- Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus, 3rd Author, 2022
- A functional population-specific variant rs77416373 in the CaV2.1 gene is associated with antidepressant treatment response in Han Chinese subjects with major depressive disorder, 3rd Author, 2022
- Functional genomics elucidates regulatory mechanisms of Parkinson's disease-associated variants, 3rd Author, 2022
- Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression, 3rd Author, 2022
- A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression, 8th Author, 2021
- Functional variants fine-mapping and gene function characterization provide insights into the role of ZNF323 in schizophrenia pathogenesis, 1st Author, 2021
- Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia, 2nd Author, 2021
- Convergent lines of evidence support NOTCH4 as a schizophrenia risk gene, 2nd Author, 2021
- The schizophrenia susceptibility gene NAGA regulates dendritic spine density: further evidence for the dendritic spine pathology of schizophrenia, 2nd Author, 2021
- A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population, 6th Author, 2020
- Regulatory mechanisms of major depressive disorder risk variants, 1st Author, 2020
- The depression GWAS risk allele predicts smaller cerebellar gray matter volume and reduced SIRT1 mRNA expression in Chinese population, 8th Author, 2019
- Integration of GWAS and brain eQTL identifies FLOT1 as a risk gene for major depressive disorder, 2nd Author, 2019
- Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk, 2nd Author, 2019
