Areas of Focus
- Epigenetic Regulation
- Transcriptional Regulation
- Chromatin Remodeling
Work Experience
- 2021-09--Present - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher, Group Leader
- 2017-11--2021-07 - Harvard Medical School - Postdoctoral Fellow
Academic Background & Achievements
- 2014-09--2017-06 PhD in Medical Biochemistry and Molecular Biology: Peking University
- 2009-09--2014-07 Bachelor of Medicine: Peking University
Publications
- Targeting RIPK1 kinase for modulating inflammation in human diseases, First Author, Co-corresponding Author, 2023
- Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, First Author, Co-corresponding Author, 2022
- A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, Co-first Author, 2020
- The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, First Author, 2017
- Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, Not mentioned, 2020
- ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, Not mentioned, 2019
- TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, Not mentioned, 2018
- Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, Not mentioned, 2018
- ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, Not mentioned, 2017
- Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, Not mentioned, 2017