Professor | Wanjin Li | Asia Growth Partners

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Name	Wanjin Li
Contact Information	Wanjinli@sioc.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Wanjin Li

Contact Information

Wanjinli@sioc.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2014-09--2017-06 PhD in Medical Biochemistry and Molecular Biology: Peking University 2009-09--2014-07 Bachelor of Medicine: Peking University
Work Experience	2021-09--Present - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher, Group Leader 2017-11--2021-07 - Harvard Medical School - Postdoctoral Fellow

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2014-09--2017-06 PhD in Medical Biochemistry and Molecular Biology: Peking University
2009-09--2014-07 Bachelor of Medicine: Peking University

Work Experience

2021-09--Present - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher, Group Leader
2017-11--2021-07 - Harvard Medical School - Postdoctoral Fellow

Areas of Focus	Epigenetic Regulation Transcriptional Regulation Chromatin Remodeling
Publications	Targeting RIPK1 kinase for modulating inflammation in human diseases, First Author, Co-corresponding Author, 2023 Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, First Author, Co-corresponding Author, 2022 A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, Co-first Author, 2020 The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, First Author, 2017 Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, Not mentioned, 2020 ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, Not mentioned, 2019 TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, Not mentioned, 2018 Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, Not mentioned, 2018 ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, Not mentioned, 2017 Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, Not mentioned, 2017

Areas of Focus

Epigenetic Regulation
Transcriptional Regulation
Chromatin Remodeling

Publications

Targeting RIPK1 kinase for modulating inflammation in human diseases, First Author, Co-corresponding Author, 2023
Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, First Author, Co-corresponding Author, 2022
A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, Co-first Author, 2020
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, First Author, 2017
Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, Not mentioned, 2020
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, Not mentioned, 2019
TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, Not mentioned, 2018
Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, Not mentioned, 2018
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, Not mentioned, 2017
Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, Not mentioned, 2017

Epigenetics Gene Expression Dna Methylation Histone Modification Chromatin Structure Transcription Factors Gene Regulation Cell Differentiation Molecular Biology Genomics

Guiying Wang - Tongji University

Yue Lou - Shanghai Normal University

Jiemin Weng - East China Normal University

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