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李婉津
Life Science
中国科学院大学
上海
Language: 中文, 英文
表观遗传学
基因表达
Dna甲基化
组蛋白修饰
染色质结构
转录因子
基因调控
细胞分化
分子生物学
基因组学
Areas of Focus
- 表观遗传学调控
- 转录调控
- 染色质重塑
Work Experience
- 2021-09--现在 - 中科院上海有机化学研究所 - 研究员、课题组长
- 2017-11--2021-07 - 哈佛大学医学院 - 博士后
Academic Background & Achievements
- 2014-09--2017-06 医学生物化学与分子生物学博士: 北京大学
- 2009-09--2014-07 医学学士: 北京大学
Publications
- Targeting RIPK1 kinase for modulating inflammation in human diseases, 第一作者，共同通讯作者, 2023
- Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, 第一作者，共同通讯作者, 2022
- A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, 共同第一作者, 2020
- The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, 第一作者, 2017
- Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, 未提及, 2020
- ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, 未提及, 2019
- TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, 未提及, 2018
- Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, 未提及, 2018
- ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, 未提及, 2017
- Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, 未提及, 2017
