Professor | 李婉津 | 数字化转型顾问

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Name

李婉津

Contact Information

Wanjinli@sioc.ac.cn

Language ability

中文, 英文

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2014-09--2017-06 医学生物化学与分子生物学博士: 北京大学 2009-09--2014-07 医学学士: 北京大学
Work Experience	2021-09--现在 - 中科院上海有机化学研究所 - 研究员、课题组长 2017-11--2021-07 - 哈佛大学医学院 - 博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	表观遗传学调控转录调控染色质重塑
Publications	Targeting RIPK1 kinase for modulating inflammation in human diseases, 第一作者，共同通讯作者, 2023 Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, 第一作者，共同通讯作者, 2022 A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, 共同第一作者, 2020 The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, 第一作者, 2017 Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, 未提及, 2020 ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, 未提及, 2019 TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, 未提及, 2018 Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, 未提及, 2018 ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, 未提及, 2017 Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, 未提及, 2017

Areas of Focus

表观遗传学调控
转录调控
染色质重塑

Publications

Targeting RIPK1 kinase for modulating inflammation in human diseases, 第一作者，共同通讯作者, 2023
Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, 第一作者，共同通讯作者, 2022
A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, 共同第一作者, 2020
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, 第一作者, 2017
Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, 未提及, 2020
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, 未提及, 2019
TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, 未提及, 2018
Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, 未提及, 2018
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, 未提及, 2017
Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, 未提及, 2017

表观遗传学基因表达 Dna甲基化组蛋白修饰染色质结构转录因子基因调控细胞分化分子生物学基因组学

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