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Yan Li
Life Science
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Biological Mass Spectrometry
Proteomics
Glycomics
Clinical Samples
Post-Translational Modifications
Expression Regulation
Human Functions
Clinical Diseases
Analysis Techniques
Methods Development
Areas of Focus
- Development of proteomics analysis techniques and methods centered on biological mass spectrometry
- Development of new glycomics analysis techniques and methods suitable for biological and clinical samples
- Research on the expression regulation of proteins and their post-translational modifications and their mechanisms in human functions and clinical diseases
Work Experience
- 2011-07 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
- 2005-10 to 2011-06 - Johns Hopkins University School of Medicine - Assistant Researcher/Postdoctoral
- 2004-01 to 2005-08 - Calibrant Biotechnology Company - Project Manager
- 2000-08 to 2004-05 - University of Maryland Department of Chemistry and Analytical Chemistry - Research Assistant
Academic Background & Achievements
- 2005-10 to 2011-06 Postdoctoral: Johns Hopkins University School of Medicine
- 2000-09 to 2004-07 Ph.D.: University of Maryland
- 1994-09 to 1998-07 Bachelor's: Peking University Health Science Center
Publications
- Human milk oligosaccharides in milk of mothers with term and preterm delivery at different lactation stage, Chuncui Huang, Yue Lu, Lin Kong, Zhendong Guo, Keli Zhao, Zheng Xiang, Xinyue Ma, Huanyu Gao, Yongfang Liu, Zhongmin Gao, Lijuan Xu, Wengang Chai, Yan Li, Yao Zhao, 2023
- GIPS-Mix for Accurate Identification of Isomeric Components in Glycan Mixtures Using Intelligent Group-Opting Strategy, Chuncui Huang, Meijie Hou, Jingyu Yan, Wengang Chai, Yan Li, Shiwei Sun, 2023
- Plasma Peptides Modulated by Protease in a Time-Dependent Manner as Effective Biomarkers for Preanalytical Quality Control, Liang Kai, Yan Li, Qianqian Li, Zhijing Song, Keli Zhao, Rong Su, Shengchun Huang, Xueyan Guo, 2023
- Proteomics and post-translational modifications analysis of umbilical mesenchymal stem cells aging, Wang, Junyan, Zhao, Keli, Chen, Ling, Zhou, Jinyu, Sun, Qing, Chen, Junhui, Su, Rong, Li, Yan, 2022
- MALDI–TOF–MS for Rapid Screening and Typing of β-Globin Variant and β-Thalassemia through Direct Measurements of Intact Globin Chains, Zhang Q. Q, Yan Li, 2022
- A stepwise mutagenesis approach using histidine and acidic amino acid to engineer highly pH-dependent protein switches, Zou, Wenjun, Huang, Chuncui, Sun, Qing, Zhao, Keli, Gao, Huanyu, Su, Rong, Li, Yan, 2022
- Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy, Liu, Lu, Xie, Wenchun, Song, Zhijing, Wang, Tianyu, Li, Xuesong, Gao, Ying, Li, Yan, Zhang, Junqing, Guo, Xiaohui, 2021
- The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor, Huang, Chuncui, Tan, Zeshun, Zhao, Keli, Zou, Wenjun, Wang, Hui, Gao, Huanyu, Sun, Shiwei, Bu, Dongbo, Chai, Wengang, Li, Yan, 2021
- Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection, Wang, Junyan, Huang, Chuncui, Zhou, Jinyu, Zhao, Keli, Li, Yan, 2021
- Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization, Song, Zhijing, Gao, Huanyu, Xie, Wenchun, Sun, Qing, Liang, Kai, Li, Yan, 2021
Awards
- Young Investigator Travel Award (2010): First Prize
- Outstanding Poster Award (2009): First Prize
- Young Investigator Travel Award (2009): First Prize
