Professor | 李岩 | 数字化转型顾问

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Name	李岩
Contact Information	yanli@ibp.ac.cn
Language ability	英语, 中文
Province	北京

Upload Avatar (500 x 500)

Name

李岩

Contact Information

yanli@ibp.ac.cn

Language ability

英语, 中文

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2005-10 至 2011-06 博士后: 约翰霍普金斯大学医学院 2000-09 至 2004-07 博士: 马里兰大学 1994-09 至 1998-07 学士: 北京大学医学部
Work Experience	2011-07 至今 - 中国科学院生物物理研究所 - 研究员 2005-10 至 2011-06 - 约翰霍普金斯大学医学院 - 助理研究员/博士后 2004-01 至 2005-08 - Calibrant生物技术公司 - 项目主管 2000-08 至 2004-05 - 马里兰大学化学与分析化学系 - 研究助理
Awards	青年研究员旅行奖 (2010): 一等奖优秀海报奖 (2009): 一等奖青年研究员旅行奖 (2009): 一等奖

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2005-10 至 2011-06 博士后: 约翰霍普金斯大学医学院
2000-09 至 2004-07 博士: 马里兰大学
1994-09 至 1998-07 学士: 北京大学医学部

Work Experience

2011-07 至今 - 中国科学院生物物理研究所 - 研究员
2005-10 至 2011-06 - 约翰霍普金斯大学医学院 - 助理研究员/博士后
2004-01 至 2005-08 - Calibrant生物技术公司 - 项目主管
2000-08 至 2004-05 - 马里兰大学化学与分析化学系 - 研究助理

Awards

青年研究员旅行奖 (2010): 一等奖
优秀海报奖 (2009): 一等奖
青年研究员旅行奖 (2009): 一等奖

Areas of Focus	开发以生物质谱为核心的多种蛋白质组学的分析技术和方法发展适用于生物样品和临床样品的新型糖组学的分析技术和方法在蛋白质组学和糖组学分析技术的基础上，主要开展针对蛋白质及其翻译后修饰的表达调控及其在人体功能和临床疾病中的作用机制的研究
Publications	Human milk oligosaccharides in milk of mothers with term and preterm delivery at different lactation stage, Chuncui Huang, Yue Lu, Lin Kong, Zhendong Guo, Keli Zhao, Zheng Xiang, Xinyue Ma, Huanyu Gao, Yongfang Liu, Zhongmin Gao, Lijuan Xu, Wengang Chai, Yan Li, Yao Zhao, 2023 GIPS-Mix for Accurate Identification of Isomeric Components in Glycan Mixtures Using Intelligent Group-Opting Strategy, Chuncui Huang, Meijie Hou, Jingyu Yan, Wengang Chai, Yan Li, Shiwei Sun, 2023 Plasma Peptides Modulated by Protease in a Time-Dependent Manner as Effective Biomarkers for Preanalytical Quality Control, Liang Kai, Yan Li, Qianqian Li, Zhijing Song, Keli Zhao, Rong Su, Shengchun Huang, Xueyan Guo, 2023 Proteomics and post-translational modifications analysis of umbilical mesenchymal stem cells aging, Wang, Junyan, Zhao, Keli, Chen, Ling, Zhou, Jinyu, Sun, Qing, Chen, Junhui, Su, Rong, Li, Yan, 2022 MALDI–TOF–MS for Rapid Screening and Typing of β-Globin Variant and β-Thalassemia through Direct Measurements of Intact Globin Chains, Zhang Q. Q, Yan Li, 2022 A stepwise mutagenesis approach using histidine and acidic amino acid to engineer highly pH-dependent protein switches, Zou, Wenjun, Huang, Chuncui, Sun, Qing, Zhao, Keli, Gao, Huanyu, Su, Rong, Li, Yan, 2022 Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy, Liu, Lu, Xie, Wenchun, Song, Zhijing, Wang, Tianyu, Li, Xuesong, Gao, Ying, Li, Yan, Zhang, Junqing, Guo, Xiaohui, 2021 The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor, Huang, Chuncui, Tan, Zeshun, Zhao, Keli, Zou, Wenjun, Wang, Hui, Gao, Huanyu, Sun, Shiwei, Bu, Dongbo, Chai, Wengang, Li, Yan, 2021 Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection, Wang, Junyan, Huang, Chuncui, Zhou, Jinyu, Zhao, Keli, Li, Yan, 2021 Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization, Song, Zhijing, Gao, Huanyu, Xie, Wenchun, Sun, Qing, Liang, Kai, Li, Yan, 2021

Areas of Focus

开发以生物质谱为核心的多种蛋白质组学的分析技术和方法
发展适用于生物样品和临床样品的新型糖组学的分析技术和方法
在蛋白质组学和糖组学分析技术的基础上，主要开展针对蛋白质及其翻译后修饰的表达调控及其在人体功能和临床疾病中的作用机制的研究

Publications

Human milk oligosaccharides in milk of mothers with term and preterm delivery at different lactation stage, Chuncui Huang, Yue Lu, Lin Kong, Zhendong Guo, Keli Zhao, Zheng Xiang, Xinyue Ma, Huanyu Gao, Yongfang Liu, Zhongmin Gao, Lijuan Xu, Wengang Chai, Yan Li, Yao Zhao, 2023
GIPS-Mix for Accurate Identification of Isomeric Components in Glycan Mixtures Using Intelligent Group-Opting Strategy, Chuncui Huang, Meijie Hou, Jingyu Yan, Wengang Chai, Yan Li, Shiwei Sun, 2023
Plasma Peptides Modulated by Protease in a Time-Dependent Manner as Effective Biomarkers for Preanalytical Quality Control, Liang Kai, Yan Li, Qianqian Li, Zhijing Song, Keli Zhao, Rong Su, Shengchun Huang, Xueyan Guo, 2023
Proteomics and post-translational modifications analysis of umbilical mesenchymal stem cells aging, Wang, Junyan, Zhao, Keli, Chen, Ling, Zhou, Jinyu, Sun, Qing, Chen, Junhui, Su, Rong, Li, Yan, 2022
MALDI–TOF–MS for Rapid Screening and Typing of β-Globin Variant and β-Thalassemia through Direct Measurements of Intact Globin Chains, Zhang Q. Q, Yan Li, 2022
A stepwise mutagenesis approach using histidine and acidic amino acid to engineer highly pH-dependent protein switches, Zou, Wenjun, Huang, Chuncui, Sun, Qing, Zhao, Keli, Gao, Huanyu, Su, Rong, Li, Yan, 2022
Addition of 3-methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy, Liu, Lu, Xie, Wenchun, Song, Zhijing, Wang, Tianyu, Li, Xuesong, Gao, Ying, Li, Yan, Zhang, Junqing, Guo, Xiaohui, 2021
The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor, Huang, Chuncui, Tan, Zeshun, Zhao, Keli, Zou, Wenjun, Wang, Hui, Gao, Huanyu, Sun, Shiwei, Bu, Dongbo, Chai, Wengang, Li, Yan, 2021
Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection, Wang, Junyan, Huang, Chuncui, Zhou, Jinyu, Zhao, Keli, Li, Yan, 2021
Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization, Song, Zhijing, Gao, Huanyu, Xie, Wenchun, Sun, Qing, Liang, Kai, Li, Yan, 2021

生物质谱蛋白质组学糖组学临床样品翻译后修饰表达调控人体功能临床疾病分析技术方法开发

李岩 - 中国科学院大学

肖华 - 上海交通大学

肖华 - 上海交通大学

Area of Focus
细胞外泌体 | 诊断 | 癌症 | 蛋白质组学 | 生物分离 | 分析技术 | 分子诊断 | 亚细胞 | 研究 | 技术

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